Results 81 to 90 of about 396,606 (377)

Counterbalancing O‐GlcNAcylation and STAT3 Phosphorylation in Ventral Tegmental Area Dopaminergic Neurons Mediates Behavioral Adaptations to Acute Restraint Stress

Advanced Science, EarlyView.
Acute restraint stress enhances STAT3Ser727 phosphorylation in dopaminergic neurons in mice. This modification promotes the upregulation of GABBR2 and GABRB3, reduces neuronal activity, and contributes to anxiety‐like behavior and diminished reward‐seeking following stress exposure.
Mingshuo Shao, Yi Wu, Haiyang Wang, Chenchun Zhang, Ying Zhu, Yan Jiang, Changyou Jiang, Qiumin Le, Xing Liu, Lan Ma, Feifei Wang   +10 more
wiley   +1 more source

Norepinephrine Induces Sertoli Cell Ferroptosis via Receptors Desensitization Causing Stress‐Related Male Reproductive Dysfunction

Advanced Science, EarlyView.
Psychological stress activates the sympathetic–adrenal axis, elevating norepinephrine (NE) and suppressing reproductive hormones, thereby impairing male reproduction. Excess NE overactivates and desensitizes β‐adrenergic receptors (β‐ARs), triggering Sertoli cell ferroptosis and disrupting spermatogenesis.
Lingyu Zhang, Shanfeng Gao, Xiaofan Xiong, Xin Liu, Rufeng Li, Xia Wang, Lin Han, Xuan Xiao, Xiaofei Wang, Wen Li, Yongxia Chang, Yuefeng Du, Juan Yang   +12 more
wiley   +1 more source

Volumetric assessment of hypothalamus in relapsing–remitting multiple sclerosis

The Egyptian Journal of Radiology and Nuclear Medicine
Background Multiple sclerosis is the most common neurodegenerative disorder worldwide. Autonomic manifestations are commonly reported in multiple sclerosis patients including sleep disturbance, depressive episodes, chronic fatigue, weight changes and ...
Sara Sameh AbdelRahman Abdallah, Amany Mohammed Rashad AbdelAziz, Mohamed Kamal Ahmed Teiba   +2 more
doaj   +1 more source

Ventromedial Hypothalamus and the Generation of Aggression

Frontiers in Systems Neuroscience, 2017
Aggression is a costly behavior, sometimes with severe consequences including death. Yet aggression is prevalent across animal species ranging from insects to humans, demonstrating its essential role in the survival of individuals and groups.
Y. Hashikawa, Koichi Hashikawa, Annegret L. Falkner, Dayu Lin   +3 more
semanticscholar   +1 more source

Timing of maternal exposure and fetal sex determine the effects of low-level chemical mixture exposure on the fetal neuroendocrine system in sheep [PDF]

, 2016
We have shown that continuous maternal exposure to the complex mixture of environmental chemicals (ECs) found in human biosolids (sewage sludge), disrupts mRNA expression of genes crucial for development and long-term regulation of hypothalamo-pituitary ...
Bellingham, M., Cotinot, C., Evans, N.P., Fowler, P.A., MacDonald, E.S., Mandon-Pepin, B., Rhind, S., Sharpe, R.M.   +7 more
core   +2 more sources

A Subcircuit in the Suprachiasmatic Nucleus Generates Wakefulness

Advanced Science, EarlyView.
This study identifies a sub‐circuit within the circadian pacemaker suprachiasmatic nucleus (SCN) that promotes arousal. This sub‐circuit is labeled by the clock output molecule mWAKE, which suppresses its excitability in a time‐dependent manner. mWAKE‐expressing cells in the SCN (SCNmWAKE cells) project to the subparaventricular zone (SPZ) to mediate ...
Qiang Liu, Sang Soo Lee, Jiali Xiong, Shahin Ahmadi, Benjamin J. Bell, Mehmet F. Keles, Mark N. Wu   +6 more
wiley   +1 more source

The Hypothalamus in Alzheimer’s Disease

Hypothalamus in Health and Diseases, 2018
deterioration of judgment,executive dysfunction,language disturbances, visuospatial disorientation, which sometimes is obvious even at the initial stages of the disease, behavioral and mood disturbances associated with personality alterations and ...
Stavros J. Baloyannis, I. Mavroudis, Demetrios Mitilineos, I. Baloyannis, V. Costa   +4 more
semanticscholar   +1 more source

Distribution of choline acetyltransferase (ChAT) immunoreactivity in the brain of the teleost cyprinus carpio [PDF]

, 2018
Cholinergic systems play a role in basic cerebral functions and its dysfunction is associated with deficit in neurodegenerative disease. Mechanisms involved in human brain diseases, are often approached by using fish models, especially cyprinids, given ...
Casini, Arianna, Cioni, Carla, Toni, Mattia, Vaccaro, Rosa   +3 more
core   +2 more sources

A Novel Transfer Learning‐Based Hybrid EEG‐fNIRS Brain‐Computer Interface for Intracerebral Hemorrhage Rehabilitation

Advanced Science, EarlyView.
The study has developed the first clinically validated hybrid EEG‐fNIRS brain‐computer interface fusion framework that systematically overcomes cross‐subject generalization barriers through a novel Wasserstein metric‐driven neural template selection mechanism.
Danyang Chen, Jian Shi, Bo Tao, Xingwei Zhao, Zhixian Zhao, Shengjie Li, Yeguang Xu, Tao Ding, Peng Zhang, Qing Ye, Kuiyou Chen, Zhuojin Wu, Yingxin Tang, Wei Jiang, Kai Shu, Li Huang, Zheng You, Ping Zhang, Zhouping Tang   +18 more
wiley   +1 more source

A prospective longitudinal study of perceived infant outcomes at 18-24 months: Neural and psychological correlates of parental thoughts and actions assessed during the first month postpartum [PDF]

, 2015
The first postpartum months constitute a critical period for parents to establish an emotional bond with their infants. Neural responses to infant-related stimuli have been associated with parental sensitivity.
Cole, Pamela M., Feldman, Ruth, Kim, Pilyoung, Leckman, James F., Mayes, Linda C., Rigo, Paola, Swain, James E.   +6 more
core   +2 more sources