Involvement of orexin neurons in fasting- and central adenosine-induced hypothermia [PDF]
Scientific Reports, 2018 We examined whether orexin neurons might play a protective role against fasting- and adenosine-induced hypothermia. We first measured body temperature (BT) in orexin neuron-ablated (ORX-AB) mice and wild-type (WT) controls during 24 hours of fasting.
Takahiro Futatsuki +6 more
doaj +4 more sources
Effect of Lonicerae japonicae Flos Carbonisata-Derived Carbon Dots on Rat Models of Fever and Hypothermia Induced by Lipopolysaccharide. [PDF]
Int J Nanomedicine, 2020 Introduction A correlation is established between the efficacy of Chinese herbal medicine and its charcoal drugs. Lonicerae japonicae Flos (LJF) is commonly used to treat fever, carbuncle, and tumors, among others.
Wu J +8 more
europepmc +2 more sources
Mild hypothermia does not attenuate platelet aggregation and may even increase ADP-stimulated platelet aggregation after clopidogrel treatment [PDF]
Thrombosis Journal, 2009 Background Mild hypothermia is currently standard of care for cardiac arrest patients in many hospitals and a common belief is that hypothermia attenuates platelet aggregation.
Erlinge David +2 more
doaj +4 more sources
Treatment of acute carbon monoxide poisoning with induced hypothermia [PDF]
Clinical and Experimental Emergency Medicine, 2016 Objective The effect of induced hypothermia on severe acute carbon monoxide (CO) poisoning remains to be addressed further. We investigated the effect of induced hypothermia on severe acute CO poisoning.
Byoung-Joon Oh +4 more
doaj +2 more sources
Phenothiazines Enhance Mild Hypothermia-induced Neuroprotection via PI3K/Akt Regulation in Experimental Stroke. [PDF]
Sci Rep, 2017 Physical hypothermia has long been considered a promising neuroprotective treatment of ischemic stroke, but the treatment’s various complications along with the impractical duration and depth of therapy significantly narrow its clinical scope.
An H +12 more
europepmc +2 more sources
Brief Rewarming Blunts Hypothermia-Induced Alterations in Sensation, Motor Drive and Cognition. [PDF]
Front Physiol, 2016 Background: It is well known that cold exposure experienced during occupational or recreational activities may adversely affect motor, cognitive performance, and health.
Brazaitis M +5 more
europepmc +2 more sources
Induced Hypothermia Does Not Harm Hemodynamics after Polytrauma: A Porcine Model
Mediators of Inflammation, 2015 Background. The deterioration of hemodynamics instantly endangers the patients’ life after polytrauma. As accidental hypothermia frequently occurs in polytrauma, therapeutic hypothermia still displays an ambivalent role as the impact on the ...
Matthias Weuster +10 more
doaj +2 more sources
Hypothermia-Induced Ubiquitination of Voltage-Dependent Anion Channel 3 Protects BV2 Microglia Cells From Cytotoxicity Following Oxygen-Glucose Deprivation/Recovery [PDF]
Frontiers in Molecular Neuroscience, 2020 Background: Hypothermia attenuates microglial activation and exerts a potential neuroprotective effect against cerebral ischemic-reperfusion (I/R) injury. However, the underlying mechanism remains to be elucidated.
Shen Zhao +12 more
doaj +2 more sources
Pharmacodynamic properties for inhibition of cAMP- and cGMP elimination by pentoxifylline remain unaltered in vitro during hypothermia [PDF]
Scandinavian Journal of Trauma, Resuscitation and Emergency Medicine, 2022 Background Rewarming from hypothermia is associated with severe complications, one of which is hypothermia-induced cardiac dysfunction. This condition is characterized by decreased cardiac output accompanied by increased total peripheral resistance. This
Anders Lund Selli +6 more
doaj +2 more sources
Hypothermia-induced dystonia and abnormal cerebellar activity in a mouse model with a single disease-mutation in the sodium-potassium pump. [PDF]
PLoS Genet, 2017 Mutations in the neuron-specific α3 isoform of the Na+/K+-ATPase are found in patients suffering from Rapid onset Dystonia Parkinsonism and Alternating Hemiplegia of Childhood, two closely related movement disorders.
Isaksen TJ +7 more
europepmc +2 more sources