Results 1 to 10 of about 74,864 (274)

Involvement of orexin neurons in fasting- and central adenosine-induced hypothermia [PDF]

Scientific Reports, 2018
We examined whether orexin neurons might play a protective role against fasting- and adenosine-induced hypothermia. We first measured body temperature (BT) in orexin neuron-ablated (ORX-AB) mice and wild-type (WT) controls during 24 hours of fasting.
Takahiro Futatsuki, Akira Yamashita, Khairunnisa Novita Ikbar, Akihiro Yamanaka, Kazunori Arita, Yasuyuki Kakihana, Tomoyuki Kuwaki   +6 more
doaj   +3 more sources

Integrated transcriptomics and metabolomics confirms the oxidative stress mechanism of hypothermia-induced neuronal necroptosis [PDF]

Cellular & Molecular Biology Letters
Abnormal climate change seriously endangers the safety of outdoor work and life, often causing hypothermia-induced coma or death. As the underlying mechanism has not been fully elucidated, a targeted treatment for hypothermia-triggered neuronal injury ...
Song-Jun Wang, Chao-Long Lu, Fu Zhang, Xue-Tong Dong, Xiao-Rui Su, Jing-Jing Sha, Bin Cong, Xia Liu   +7 more
doaj   +2 more sources

Hypothermia-Induced Ubiquitination of Voltage-Dependent Anion Channel 3 Protects BV2 Microglia Cells From Cytotoxicity Following Oxygen-Glucose Deprivation/Recovery [PDF]

Frontiers in Molecular Neuroscience, 2020
Background: Hypothermia attenuates microglial activation and exerts a potential neuroprotective effect against cerebral ischemic-reperfusion (I/R) injury. However, the underlying mechanism remains to be elucidated.
Shen Zhao, Shen Zhao, Peng Xiao, Peng Xiao, Hao Cui, Hao Cui, Ping Gong, Caijing Lin, Caijing Lin, Feng Chen, Feng Chen, Ziren Tang, Ziren Tang   +12 more
doaj   +2 more sources

Targeted Temperature Management in Pregnant Patients after Cardiac Arrest: A Systematic Review [PDF]

Iranian Journal of Medical Sciences
Background: Targeted temperature management (TTM) is a standard care intervention following resuscitation, known to improve neurological outcomes in patients.
Sina Azadikhah Jahromi, Mina Ostovan, Razieh Zahedi, Zhila Rahmanian, Pegah Abdollahzadeh   +4 more
doaj   +2 more sources

Hypothermia-Mediated Apoptosis and Inflammation Contribute to Antioxidant and Immune Adaption in Freshwater Drum, Aplodinotus grunniens

Antioxidants, 2022
Hypothermia-exposure-induced oxidative stress dysregulates cell fate and perturbs cellular homeostasis and function, thereby disturbing fish health. To evaluate the impact of hypothermia on the freshwater drum (Aplodinotus grunniens), an 8-day experiment
Jianxiang Chen, Hongxia Li, Pao Xu, Yongkai Tang, Shenyan Su, Guangxiang Liu, Ningyuan Wu, Miaomiao Xue, Fan Yu, Wenrong Feng, Changyou Song, Haibo Wen   +11 more
doaj   +1 more source

Comparison of Uncontrolled and Device-Induced Therapeutic Hypothermia in Newborn Infants with Hypoxic Ischemic Encephalopathy

Acta Biomedica Scientifica, 2021
Background. Newborn infants who have undergone severe birth asphyxia have a high risk of neurological disorders and death. The most effective method for the treatment of hypoxic ischemic encephalopathy caused by intrapartum asphyxia is therapeutic ...
A. A. Zarubin, E. S. Filippov, A. S. Vanyarkina, O. G. Ivanova, A. A. Shishkina   +4 more
doaj   +1 more source

Hypothermia-Induced Hypokalemia [PDF]

Military Medicine, 1998
Hypothermia may be seen both as a presenting problem and as a part of therapeutic strategy. An illustrative case is presented. In our case of severe head trauma, hypothermia was used as a therapeutic modality to minimize the brain injury. While hypothermic, the patient developed severe hypokalemia and was supplemented with 400 mEq of potassium.
Anthony W. Zydlewski, James A. Hasbargen
openaire   +3 more sources

Treatment of acute carbon monoxide poisoning with induced hypothermia [PDF]

Clinical and Experimental Emergency Medicine, 2016
Objective The effect of induced hypothermia on severe acute carbon monoxide (CO) poisoning remains to be addressed further. We investigated the effect of induced hypothermia on severe acute CO poisoning.
Byoung-Joon Oh, Yong-Gyun Im, Eunjung Park, Young-Gi Min, Sang-Cheon Choi   +4 more
doaj   +1 more source

Effects of local hypothermia-rewarming on physiology, metabolism and inflammation of acutely injured human spinal cord. [PDF]

, 2020
In five patients with acute, severe thoracic traumatic spinal cord injuries (TSCIs), American spinal injuries association Impairment Scale (AIS) grades A-C, we induced cord hypothermia (33 °C) then rewarming (37 °C).
A Bricolo, A Mizuma, A Schubert, C Hochstim, DW Marion, GL Clifton, GV Varsos, HA Choi, I Phang, I Phang, JR Bethea, K Chatzipanteli, K Chatzipanteli, KL Carpenter, L Zhu, M Dididze, M Erecinska, MC Werndle, MC Werndle, MJ Gallagher, PE Batchelor, PJ Andrews, PJ Hutchinson, RR Hansebout, S Chen, S Saadoun, S Shibuya, SR Lewis, TP Lo Jr.   +28 more
core   +1 more source

Phenytoin-induced hypothermia [PDF]

BMJ Case Reports, 2019
A 60-year-old man with cerebral palsy and epilepsy was admitted with acute lethargy and deterioration in coordination. He was noted to be hypothermic at 35°C on admission. Routine work-up revealed toxic levels of phenytoin. No cause of hypothermia could be identified but as his phenytoin levels normalised, his body temperature also improved.
Marianne Watters, Pamela Everitt, Hilary Wilson   +2 more
openaire   +3 more sources