Results 1 to 10 of about 7,577,465 (338)

Involvement of orexin neurons in fasting- and central adenosine-induced hypothermia [PDF]

Scientific Reports, 2018
We examined whether orexin neurons might play a protective role against fasting- and adenosine-induced hypothermia. We first measured body temperature (BT) in orexin neuron-ablated (ORX-AB) mice and wild-type (WT) controls during 24 hours of fasting.
Takahiro Futatsuki, Akira Yamashita, Khairunnisa Novita Ikbar, Akihiro Yamanaka, Kazunori Arita, Yasuyuki Kakihana, Tomoyuki Kuwaki   +6 more
doaj   +4 more sources

Effect of Lonicerae japonicae Flos Carbonisata-Derived Carbon Dots on Rat Models of Fever and Hypothermia Induced by Lipopolysaccharide. [PDF]

Int J Nanomedicine, 2020
Introduction A correlation is established between the efficacy of Chinese herbal medicine and its charcoal drugs. Lonicerae japonicae Flos (LJF) is commonly used to treat fever, carbuncle, and tumors, among others.
Wu J, Zhang M, Cheng J, Zhang Y, Luo J, Liu Y, Kong H, Qu H, Zhao Y.   +8 more
europepmc   +2 more sources

Hypothermia-Induced Electrocardiographic Changes. [PDF]

Arq Bras Cardiol, 2020
This is an open-access article distributed under the terms of the Creative Commons Attribution License.
Marques A, Caldeira D, Briosa A, João I, Pereira H.   +4 more
europepmc   +4 more sources

Integrated transcriptomics and metabolomics confirms the oxidative stress mechanism of hypothermia-induced neuronal necroptosis [PDF]

Cellular & Molecular Biology Letters
Abnormal climate change seriously endangers the safety of outdoor work and life, often causing hypothermia-induced coma or death. As the underlying mechanism has not been fully elucidated, a targeted treatment for hypothermia-triggered neuronal injury ...
Song-Jun Wang, Chao-Long Lu, Fu Zhang, Xue-Tong Dong, Xiao-Rui Su, Jing-Jing Sha, Bin Cong, Xia Liu   +7 more
doaj   +2 more sources

Hypothermia-Induced Ubiquitination of Voltage-Dependent Anion Channel 3 Protects BV2 Microglia Cells From Cytotoxicity Following Oxygen-Glucose Deprivation/Recovery [PDF]

Frontiers in Molecular Neuroscience, 2020
Background: Hypothermia attenuates microglial activation and exerts a potential neuroprotective effect against cerebral ischemic-reperfusion (I/R) injury. However, the underlying mechanism remains to be elucidated.
Shen Zhao, Shen Zhao, Peng Xiao, Peng Xiao, Hao Cui, Hao Cui, Ping Gong, Caijing Lin, Caijing Lin, Feng Chen, Feng Chen, Ziren Tang, Ziren Tang   +12 more
doaj   +2 more sources

Induced Hypothermia Does Not Harm Hemodynamics after Polytrauma: A Porcine Model

Mediators of Inflammation, 2015
Background. The deterioration of hemodynamics instantly endangers the patients’ life after polytrauma. As accidental hypothermia frequently occurs in polytrauma, therapeutic hypothermia still displays an ambivalent role as the impact on the ...
Matthias Weuster, Philipp Mommsen, Roman Pfeifer, Juliane Mohr, Steffen Ruchholtz, Sascha Flohé, Matthias Fröhlich, Claudia Keibl, Andreas Seekamp, Martijn van Griensven, Ingo Witte   +10 more
doaj   +2 more sources

The RNA-binding protein RBM3 is involved in hypothermia induced neuroprotection

Neurobiology of Disease, 2011
Induced hypothermia is the only therapy with proven efficacy to reduce brain damage after perinatal asphyxia. While hypothermia down-regulates global protein synthesis and cell metabolism, low temperature induces a small subset of proteins that includes ...
Sophorn Chip, Andrea Zelmer, Omolara O. Ogunshola, Ursula Felderhoff-Mueser, Cordula Nitsch, Christoph Bührer, Sven Wellmann   +6 more
doaj   +2 more sources

Hypothermia after Cardiac Arrest in Large Animals (HACA-LA): a randomized controlled experimental study [PDF]

Intensive Care Medicine Experimental
Background Induced hypothermia after cardiac arrest is neuroprotective in several animal models of cardiac arrest, but few high-quality studies have been conducted in larger animals.
Olof Persson, Anna Valerianova, Leos Tejkl, Jan Bělohlávek, Tobias Cronberg, Niklas Nielsen, Attila Frigyesi, Susann Ullén, Wolfgang Weihs, Alexandra-Maria Stommel, Kaj Blennow, Henrik Zetterberg, Sandra Högler, Elisabet Englund, Mikuláš Mlček, Hans Friberg   +15 more
doaj   +2 more sources

Hypothermia-Mediated Apoptosis and Inflammation Contribute to Antioxidant and Immune Adaption in Freshwater Drum, Aplodinotus grunniens

Antioxidants, 2022
Hypothermia-exposure-induced oxidative stress dysregulates cell fate and perturbs cellular homeostasis and function, thereby disturbing fish health. To evaluate the impact of hypothermia on the freshwater drum (Aplodinotus grunniens), an 8-day experiment
Jianxiang Chen, Hongxia Li, Pao Xu, Yongkai Tang, Shenyan Su, Guangxiang Liu, Ningyuan Wu, Miaomiao Xue, Fan Yu, Wenrong Feng, Changyou Song, Haibo Wen   +11 more
doaj   +1 more source

Comparison of Uncontrolled and Device-Induced Therapeutic Hypothermia in Newborn Infants with Hypoxic Ischemic Encephalopathy

Acta Biomedica Scientifica, 2021
Background. Newborn infants who have undergone severe birth asphyxia have a high risk of neurological disorders and death. The most effective method for the treatment of hypoxic ischemic encephalopathy caused by intrapartum asphyxia is therapeutic ...
A. A. Zarubin, E. S. Filippov, A. S. Vanyarkina, O. G. Ivanova, A. A. Shishkina   +4 more
doaj   +1 more source