Results 1 to 10 of about 6,425,252 (325)

Involvement of orexin neurons in fasting- and central adenosine-induced hypothermia [PDF]

Scientific Reports, 2018
We examined whether orexin neurons might play a protective role against fasting- and adenosine-induced hypothermia. We first measured body temperature (BT) in orexin neuron-ablated (ORX-AB) mice and wild-type (WT) controls during 24 hours of fasting.
Takahiro Futatsuki, Akira Yamashita, Khairunnisa Novita Ikbar, Akihiro Yamanaka, Kazunori Arita, Yasuyuki Kakihana, Tomoyuki Kuwaki   +6 more
doaj   +4 more sources

Effect of Lonicerae japonicae Flos Carbonisata-Derived Carbon Dots on Rat Models of Fever and Hypothermia Induced by Lipopolysaccharide. [PDF]

Int J Nanomedicine, 2020
Introduction A correlation is established between the efficacy of Chinese herbal medicine and its charcoal drugs. Lonicerae japonicae Flos (LJF) is commonly used to treat fever, carbuncle, and tumors, among others.
Wu J, Zhang M, Cheng J, Zhang Y, Luo J, Liu Y, Kong H, Qu H, Zhao Y.   +8 more
europepmc   +2 more sources

Treatment of acute carbon monoxide poisoning with induced hypothermia [PDF]

Clinical and Experimental Emergency Medicine, 2016
Objective The effect of induced hypothermia on severe acute carbon monoxide (CO) poisoning remains to be addressed further. We investigated the effect of induced hypothermia on severe acute CO poisoning.
Byoung-Joon Oh, Yong-Gyun Im, Eunjung Park, Young-Gi Min, Sang-Cheon Choi   +4 more
doaj   +2 more sources

Phenothiazines Enhance Mild Hypothermia-induced Neuroprotection via PI3K/Akt Regulation in Experimental Stroke. [PDF]

Sci Rep, 2017
Physical hypothermia has long been considered a promising neuroprotective treatment of ischemic stroke, but the treatment’s various complications along with the impractical duration and depth of therapy significantly narrow its clinical scope.
An H, Duan Y, Wu D, Yip J, Elmadhoun O, Wright JC, Shi W, Liu K, He X, Shi J, Jiang F, Ji X, Ding Y.   +12 more
europepmc   +2 more sources

Hypothermia-Induced Ubiquitination of Voltage-Dependent Anion Channel 3 Protects BV2 Microglia Cells From Cytotoxicity Following Oxygen-Glucose Deprivation/Recovery [PDF]

Frontiers in Molecular Neuroscience, 2020
Background: Hypothermia attenuates microglial activation and exerts a potential neuroprotective effect against cerebral ischemic-reperfusion (I/R) injury. However, the underlying mechanism remains to be elucidated.
Shen Zhao, Shen Zhao, Peng Xiao, Peng Xiao, Hao Cui, Hao Cui, Ping Gong, Caijing Lin, Caijing Lin, Feng Chen, Feng Chen, Ziren Tang, Ziren Tang   +12 more
doaj   +2 more sources

Induced Hypothermia Does Not Harm Hemodynamics after Polytrauma: A Porcine Model

Mediators of Inflammation, 2015
Background. The deterioration of hemodynamics instantly endangers the patients’ life after polytrauma. As accidental hypothermia frequently occurs in polytrauma, therapeutic hypothermia still displays an ambivalent role as the impact on the ...
Matthias Weuster, Philipp Mommsen, Roman Pfeifer, Juliane Mohr, Steffen Ruchholtz, Sascha Flohé, Matthias Fröhlich, Claudia Keibl, Andreas Seekamp, Martijn van Griensven, Ingo Witte   +10 more
doaj   +2 more sources

The RNA-binding protein RBM3 is involved in hypothermia induced neuroprotection

Neurobiology of Disease, 2011
Induced hypothermia is the only therapy with proven efficacy to reduce brain damage after perinatal asphyxia. While hypothermia down-regulates global protein synthesis and cell metabolism, low temperature induces a small subset of proteins that includes ...
Sophorn Chip, Andrea Zelmer, Omolara O. Ogunshola, Ursula Felderhoff-Mueser, Cordula Nitsch, Christoph Bührer, Sven Wellmann   +6 more
doaj   +2 more sources

Targeted Temperature Management in Pregnant Patients after Cardiac Arrest: A Systematic Review [PDF]

Iranian Journal of Medical Sciences
Background: Targeted temperature management (TTM) is a standard care intervention following resuscitation, known to improve neurological outcomes in patients.
Sina Azadikhah Jahromi, Mina Ostovan, Razieh Zahedi, Zhila Rahmanian, Pegah Abdollahzadeh   +4 more
doaj   +2 more sources

Hypothermia-Mediated Apoptosis and Inflammation Contribute to Antioxidant and Immune Adaption in Freshwater Drum, Aplodinotus grunniens

Antioxidants, 2022
Hypothermia-exposure-induced oxidative stress dysregulates cell fate and perturbs cellular homeostasis and function, thereby disturbing fish health. To evaluate the impact of hypothermia on the freshwater drum (Aplodinotus grunniens), an 8-day experiment
Jianxiang Chen, Hongxia Li, Pao Xu, Yongkai Tang, Shenyan Su, Guangxiang Liu, Ningyuan Wu, Miaomiao Xue, Fan Yu, Wenrong Feng, Changyou Song, Haibo Wen   +11 more
doaj   +1 more source

Comparison of Uncontrolled and Device-Induced Therapeutic Hypothermia in Newborn Infants with Hypoxic Ischemic Encephalopathy

Acta Biomedica Scientifica, 2021
Background. Newborn infants who have undergone severe birth asphyxia have a high risk of neurological disorders and death. The most effective method for the treatment of hypoxic ischemic encephalopathy caused by intrapartum asphyxia is therapeutic ...
A. A. Zarubin, E. S. Filippov, A. S. Vanyarkina, O. G. Ivanova, A. A. Shishkina   +4 more
doaj   +1 more source