Results 31 to 40 of about 6,425,252 (325)

Role of nitric oxide in hypoxia-induced hyperventilation and hypothermia: participation of the locus coeruleus

Brazilian Journal of Medical and Biological Research, 1999
Hypoxia elicits hyperventilation and hypothermia, but the mechanisms involved are not well understood. The nitric oxide (NO) pathway is involved in hypoxia-induced hypothermia and hyperventilation, and works as a neuromodulator in the central nervous ...
G. Fabris, J.A. Anselmo-Franci, L.G.S. Branco   +2 more
doaj   +1 more source

The effectiveness of low-dose desmopressin in improving hypothermia-induced impairment of primary haemostasis under influence of aspirin – a randomized controlled trial

BMC Anesthesiology, 2015
BackgroundMild hypothermia (34–35 °C) increases perioperative blood loss. Our previous studies showed that desmopressin could have in vitro beneficial effects on hypothermia-induced primary haemostasis impairment.
Pui Yee Tsui, C. Cheung, Yvonne Lee, S. Leung, K. Ng   +4 more
semanticscholar   +1 more source

Limited Therapeutic Time Windows of Mild-to-Moderate Hypothermia in a Focal Ischemia Model in Rat

Stroke Research and Treatment, 2011
Although many studies have shown the great potential of induced hypothermia in stroke treatment, we recognize that there are limitations to the protective effects of hypothermia even in the laboratory.
Heng Zhao, Gary Steinberg
doaj   +1 more source

Targeted temperature management in neurointensive care

Chinese Journal of Contemporary Neurology and Neurosurgery, 2023
The clinical prognosis of acute severe brain injury is poor, and therapeutic hypothermia in targeted temperature management (TTM) is considered to be one of the most effective neuroprotective methods, which might effectively improve the prognosis of ...
QU Xin, ZHAO Hao, SHANG Feng, WANG Ning
doaj   +1 more source

Induced and Accidental Hypothermia

Critical Care and Resuscitation, 2000
To review human thermoregulation and the pathophysiology and management of induced and accidental hypothermia.A review of studies reported over ten years from 1990 to 2000 and identified through a MEDLINE search of the English-language literature on thermoregulation and induced and accidental hypothermia.Hypothermia is defined as a core temperature ...
E, Connolly, L I, Worthley
openaire   +2 more sources

Global SUMOylation is a molecular mechanism underlying hypothermia-induced ischemic tolerance

Frontiers in Cellular Neuroscience, 2014
The molecular mechanisms underlying hypothermic neuroprotection have yet to be fully elucidated. Herein we demonstrate that global SUMOylation, a form of post-translational modification with the Small Ubiquitin-like MOdifer, participates in the ...
Yang-ja Lee, Yongshan Mou, D. Klimanis, J. Bernstock, J. Hallenbeck   +4 more
semanticscholar   +1 more source

Randomized preclinical study of machine perfusion in vascularized composite allografts

BJS (British Journal of Surgery), EarlyView., 2020
This study was designed to identify the optimum machine perfusion parameters for preservation of limbs before transplantation, and determine whether this was better than cold storage. Normothermic machine perfusion at a pressure of 70 mmHg (NMP‐70) provided superior preservation to cold storage after transplantation.
K. R. Amin, J. P. Stone, J. Kerr, A. Geraghty, L. Joseph, A. Montero‐Fernandez, J. K. Wong, J. E. Fildes   +7 more
wiley   +1 more source

Comparison between Gel Pad Cooling Device and Water Blanket during Target Temperature Management in Cardiac Arrest Patients [PDF]

Acute and Critical Care, 2018
Background: Target temperature management (TTM) improves neurological outcomes for comatose survivors of out-of-hospital cardiac arrest. We compared the efficacy and safety of a gel pad cooling device (GP) and a water blanket (WB) during TTM. Methods: We
Yoon Sun Jung, Kyung Su Kim, Gil Joon Suh, Jun-Hwi Cho   +3 more
doaj   +1 more source

Viability assessment and transplantation of fatty liver grafts using end‐ischemic normothermic machine perfusion

Liver Transplantation, EarlyView., 2022
Abstract End‐ischemic viability testing by normothermic machine perfusion (NMP) represents an effective strategy to recover liver grafts having initially been discarded for liver transplantation (LT). However, its results in the setting of significant (≥30%) macrovesicular steatosis (MaS) have not been specifically assessed.
Damiano Patrono, Riccardo De Carlis, Alessandro Gambella, Francesca Farnesi, Alice Podestà, Andrea Lauterio, Francesco Tandoi, Luciano De Carlis, Renato Romagnoli   +8 more
wiley   +1 more source

Cold at the Core: Osborn Waves in Neurosarcoidosis-Induced Central Hypothermia

Case Reports in Cardiology, 2019
Osborn waves, or J waves, initially described by John Osborn in 1953 in hypothermic dog experiments, are highly sensitive and specific for hypothermia. Initially thought to be secondary to a hypothermia-induced “injury current,” they have more recently ...
Gregory Scott Troutman, Jason Salamon, Matthew Scharf, Jeremy A. Mazurek   +3 more
doaj   +1 more source