Results 31 to 40 of about 74,864 (274)

Hypothermia Reduces Mortality, Prevents the Calcium Plateau, and Is Neuroprotective Following Status Epilepticus in Rats

Frontiers in Neurology, 2018
Status Epilepticus (SE) is a major neurological emergency and is considered a leading cause of Acquired Epilepsy (AE). We have shown that SE produces neuronal injury and prolonged alterations in hippocampal calcium levels ([Ca2+]i) that may underlie the ...
Kristin F. Phillips, Laxmikant S. Deshpande, Laxmikant S. Deshpande, Robert J. DeLorenzo, Robert J. DeLorenzo   +4 more
doaj   +1 more source

Viability assessment and transplantation of fatty liver grafts using end‐ischemic normothermic machine perfusion

Liver Transplantation, EarlyView., 2022
Abstract End‐ischemic viability testing by normothermic machine perfusion (NMP) represents an effective strategy to recover liver grafts having initially been discarded for liver transplantation (LT). However, its results in the setting of significant (≥30%) macrovesicular steatosis (MaS) have not been specifically assessed.
Damiano Patrono, Riccardo De Carlis, Alessandro Gambella, Francesca Farnesi, Alice Podestà, Andrea Lauterio, Francesco Tandoi, Luciano De Carlis, Renato Romagnoli   +8 more
wiley   +1 more source

Mild hypothermia does not attenuate platelet aggregation and may even increase ADP-stimulated platelet aggregation after clopidogrel treatment

Thrombosis Journal, 2009
Background Mild hypothermia is currently standard of care for cardiac arrest patients in many hospitals and a common belief is that hypothermia attenuates platelet aggregation.
Erlinge David, Högberg Carl, Braun Oscar Ö   +2 more
doaj   +1 more source

Cold at the Core: Osborn Waves in Neurosarcoidosis-Induced Central Hypothermia

Case Reports in Cardiology, 2019
Osborn waves, or J waves, initially described by John Osborn in 1953 in hypothermic dog experiments, are highly sensitive and specific for hypothermia. Initially thought to be secondary to a hypothermia-induced “injury current,” they have more recently ...
Gregory Scott Troutman, Jason Salamon, Matthew Scharf, Jeremy A. Mazurek   +3 more
doaj   +1 more source

Targeted temperature management in neurointensive care

Chinese Journal of Contemporary Neurology and Neurosurgery, 2023
The clinical prognosis of acute severe brain injury is poor, and therapeutic hypothermia in targeted temperature management (TTM) is considered to be one of the most effective neuroprotective methods, which might effectively improve the prognosis of ...
QU Xin, ZHAO Hao, SHANG Feng, WANG Ning
doaj   +1 more source

A case report of acute hypothermia during initial inpatient clozapine titration with review of current literature on clozapine-induced temperature dysregulations

BMC Psychiatry, 2020
Background Here we describe a unique case of clozapine-associated hypothermia during initial titration of this medication in an acute inpatient psychiatry setting. Only a handful of cases on this topic have been published.
Bradley G. Burk, Alex H. Ward, Brooke Clark   +2 more
doaj   +1 more source

Outcome and current status of therapeutic hypothermia after out-of-hospital cardiac arrest in Korea using data from the Korea Hypothermia Network registry [PDF]

Clinical and Experimental Emergency Medicine, 2014
ObjectiveTherapeutic hypothermia (TH) has become the standard strategy for reducing brain damage in the postresuscitation period. The aim of this study was to investigate current TH performance and outcomes in out-of-hospital cardiac arrest (OHCA ...
Byung Kook Lee, Kyu Nam Park, Gu Hyun Kang, Kyung Hwan Kim, Giwoon Kim, Won Young Kim, Jin Hong Min, Yooseok Park, Jung Bae Park, Gil Joon Suh, Yoo Dong Son, Jonghwan Shin, Joo Suk Oh, Yeon Ho You, Dong Hoon Lee, Jong Seok Lee, Hoon Lim, Tae Chang Jang, Gyu Chong Cho, In Soo Cho, Kyoung Chul Cha, Seung Pill Choi, Wook Jin Choi, Chul Han,   +24 more
doaj   +1 more source

The RNA-binding protein RBM3 is involved in hypothermia induced neuroprotection

Neurobiology of Disease, 2011
Induced hypothermia is the only therapy with proven efficacy to reduce brain damage after perinatal asphyxia. While hypothermia down-regulates global protein synthesis and cell metabolism, low temperature induces a small subset of proteins that includes ...
Sophorn Chip, Andrea Zelmer, Omolara O. Ogunshola, Ursula Felderhoff-Mueser, Cordula Nitsch, Christoph Bührer, Sven Wellmann   +6 more
doaj   +1 more source

Effect of Trans-Nasal Evaporative Intra-arrest Cooling on Functional Neurologic Outcome in Out-of-Hospital Cardiac Arrest : The PRINCESS Randomized Clinical Trial [PDF]

, 2019
© 2019 American Medical Association. All rights reserved.Importance: Therapeutic hypothermia may increase survival with good neurologic outcome after cardiac arrest.
Abella, Abou-Chebl, Adeline Higuet, Anatolij Truhlar, Bernard, Bernard, Busch, Callaway, Caroline Busche, Castrén, Che, David Konrad, Debaty, Didier Desruelles, Emelie Dillenbeck, Fabio Silvio Taccone, Fernando Rosell Ortiz, Francisco Carmona Jiménes, Froehler, Hans-Jörg Busch, Hypothermia after Cardiac Arrest Study Group, Jacob Hollenberg, Jacques Creteur, Jean-Louis Vincent, Jennett, Jerome Cuny, Johan Peterson, Julia Williams, Kim, Leif Svensson, Martin Jonsson, Mattias Ringh, Nick Vermeersch, Nielsen, Nolan, Nolan, Nordberg, Patrick Goldstein, Per Nordberg, Perkins, Scolletta, Sune Forsberg, Yu, Zhang   +43 more
core   +3 more sources

Induced Hypothermia for Acute Stroke [PDF]

Stroke, 2007
Induced hypothermia is one of the most promising neuroprotective therapies. Technological limitations and homeostatic mechanisms that maintain core body temperature have impeded the clinical use of hypothermia. Recent advances in intravascular cooling catheters and successful trials of hypothermia for cardiac arrest and neonatal asphyxia renewed ...
Patrick D. Lyden, Thomas M. Hemmen
openaire   +2 more sources