Results 41 to 50 of about 6,488,196 (247)
BackgroundMild hypothermia (34–35 °C) increases perioperative blood loss. Our previous studies showed that desmopressin could have in vitro beneficial effects on hypothermia-induced primary haemostasis impairment.
Pui Yee Tsui+4 more
semanticscholar +1 more source
Use of an external-cooling device for the treatment of heat stroke [PDF]
Heat stroke is caused by losing control of one’s body temperature. It can be life threatening without proper treatment. In this case report, we describe a heat stroke patient treated with an external-cooling device, which is commonly used for therapeutic
Byung-Chan Lee+3 more
doaj +1 more source
Post-TTM Rebound Pyrexia after Ischemia-Reperfusion Injury Results in Sterile Inflammation and Apoptosis in Cardiomyocytes [PDF]
Introduction. Fever is frequently observed after acute ischemic events and is associated with poor outcome and higher mortality. Targeted temperature management (TTM) is recommended for neuroprotection in comatose cardiac arrest survivors, but pyrexia ...
Berger, Felix+6 more
core +1 more source
Global SUMOylation is a molecular mechanism underlying hypothermia-induced ischemic tolerance
The molecular mechanisms underlying hypothermic neuroprotection have yet to be fully elucidated. Herein we demonstrate that global SUMOylation, a form of post-translational modification with the Small Ubiquitin-like MOdifer, participates in the ...
Yang-ja Lee+4 more
semanticscholar +1 more source
Cold at the Core: Osborn Waves in Neurosarcoidosis-Induced Central Hypothermia
Osborn waves, or J waves, initially described by John Osborn in 1953 in hypothermic dog experiments, are highly sensitive and specific for hypothermia. Initially thought to be secondary to a hypothermia-induced “injury current,” they have more recently ...
Gregory Scott Troutman+3 more
doaj +1 more source
Targeted temperature management in neurointensive care
The clinical prognosis of acute severe brain injury is poor, and therapeutic hypothermia in targeted temperature management (TTM) is considered to be one of the most effective neuroprotective methods, which might effectively improve the prognosis of ...
QU Xin, ZHAO Hao, SHANG Feng, WANG Ning
doaj +1 more source
Enhanced Neuroprotective Effects by Inter-Ischemia Hypothermia in Cerebral Stroke [PDF]
Background and Purpose. Studies have shown that inter-ischemia hypothermia is able to reduce the size of myocardial infarctions and improve their clinical outcomes.
Ding, Yuchuan+4 more
core +1 more source
Therapeutic Hypothermia in Children and Adults with Severe Traumatic Brain Injury. [PDF]
Great expectations have been raised about neuroprotection of therapeutic hypothermia in patients with traumatic brain injury (TBI) by analogy with its effects after heart arrest, neonatal asphyxia, and drowning in cold water.
Grände, Per-Olof+2 more
core +1 more source
Background—Hypothermia has been reported to induce ventricular tachycardia and fibrillation (VT/VF) in patients with early repolarization (ER) pattern.
Z. Gurabi+4 more
semanticscholar +1 more source
Status Epilepticus (SE) is a major neurological emergency and is considered a leading cause of Acquired Epilepsy (AE). We have shown that SE produces neuronal injury and prolonged alterations in hippocampal calcium levels ([Ca2+]i) that may underlie the ...
Kristin F. Phillips+4 more
doaj +1 more source