Results 41 to 50 of about 6,581,632 (222)

Global SUMOylation is a molecular mechanism underlying hypothermia-induced ischemic tolerance

Frontiers in Cellular Neuroscience, 2014
The molecular mechanisms underlying hypothermic neuroprotection have yet to be fully elucidated. Herein we demonstrate that global SUMOylation, a form of post-translational modification with the Small Ubiquitin-like MOdifer, participates in the ...
Yang-ja Lee, Yongshan Mou, D. Klimanis, J. Bernstock, J. Hallenbeck   +4 more
semanticscholar   +1 more source

Mild hypothermia does not attenuate platelet aggregation and may even increase ADP-stimulated platelet aggregation after clopidogrel treatment

Thrombosis Journal, 2009
Background Mild hypothermia is currently standard of care for cardiac arrest patients in many hospitals and a common belief is that hypothermia attenuates platelet aggregation.
Erlinge David, Högberg Carl, Braun Oscar Ö   +2 more
doaj   +1 more source

Scalp cooling with adjuvant/neoadjuvant chemotherapy for breast cancer and the risk of scalp metastases: systematic review and meta-analysis. [PDF]

, 2017
PurposeThe risk of scalp metastases in patients using scalp cooling for preservation of hair during chemotherapy has been a concern but is poorly described.MethodsA systematic review and meta-analysis of longitudinal studies was undertaken to evaluate ...
Melin, Susan A, Rugo, Hope S, Voigt, Jeff   +2 more
core   +1 more source

Cold at the Core: Osborn Waves in Neurosarcoidosis-Induced Central Hypothermia

Case Reports in Cardiology, 2019
Osborn waves, or J waves, initially described by John Osborn in 1953 in hypothermic dog experiments, are highly sensitive and specific for hypothermia. Initially thought to be secondary to a hypothermia-induced “injury current,” they have more recently ...
Gregory Scott Troutman, Jason Salamon, Matthew Scharf, Jeremy A. Mazurek   +3 more
doaj   +1 more source

Outcome and current status of therapeutic hypothermia after out-of-hospital cardiac arrest in Korea using data from the Korea Hypothermia Network registry [PDF]

Clinical and Experimental Emergency Medicine, 2014
ObjectiveTherapeutic hypothermia (TH) has become the standard strategy for reducing brain damage in the postresuscitation period. The aim of this study was to investigate current TH performance and outcomes in out-of-hospital cardiac arrest (OHCA ...
Byung Kook Lee, Kyu Nam Park, Gu Hyun Kang, Kyung Hwan Kim, Giwoon Kim, Won Young Kim, Jin Hong Min, Yooseok Park, Jung Bae Park, Gil Joon Suh, Yoo Dong Son, Jonghwan Shin, Joo Suk Oh, Yeon Ho You, Dong Hoon Lee, Jong Seok Lee, Hoon Lim, Tae Chang Jang, Gyu Chong Cho, In Soo Cho, Kyoung Chul Cha, Seung Pill Choi, Wook Jin Choi, Chul Han,   +24 more
doaj   +1 more source

Hypothermia-induced acute kidney injury in an elderly patient

The Korean Journal of Internal Medicine, 2014
Hypothermia, defined as an unintentional decline in the core body temperature to below 35℃, is a life-threatening condition. Patients with malnutrition and diabetes mellitus as well as those of advanced age are at high risk for accidental hypothermia ...
H. Yoon, Mun Chul Kim, Jae Woo Park, Min A Yang, Cheon Beom Lee, I. Sun, K. Lee   +6 more
semanticscholar   +1 more source

A case report of acute hypothermia during initial inpatient clozapine titration with review of current literature on clozapine-induced temperature dysregulations

BMC Psychiatry, 2020
Background Here we describe a unique case of clozapine-associated hypothermia during initial titration of this medication in an acute inpatient psychiatry setting. Only a handful of cases on this topic have been published.
Bradley G. Burk, Alex H. Ward, Brooke Clark   +2 more
doaj   +1 more source

Enhanced sensitivity of postsynaptic serotonin-1A receptors in rats and mice with high trait aggression [PDF]

, 2001
Individual differences in aggressive behaviour have been linked to variability in central serotonergic activity, both in humans and animals. A previous experiment in mice, selectively bred for high or low levels of aggression, showed an up-regulation of ...
Boer, Sietse F. de,, Buwalda, Bauke,, Jong, Jelly G. de,, Koolhaas, Jaap M.,, Ruiter, Anne J.H. de,, Vegt, Bea J. van der,   +5 more
core   +1 more source

Mild hypothermia reduces endoplasmic reticulum stress‐induced apoptosis and improves neuronal functions after severe traumatic brain injury

Brain and Behavior, 2019
Mild hypothermia is wildly used in clinical treatment of traumatic brain injury (TBI). However, the effect of mild hypothermia on endoplasmic reticulum (ER) stress‐induced apoptosis after severe TBI is still unknown.
Chuan-fang Wang, Cheng-cheng Zhao, Yi He, Zong-yang Li, Wen-Lan Liu, Xian-jian Huang, Yuefei Deng, Weiping Li   +7 more
semanticscholar   +1 more source

Induced Hypothermia for Acute Stroke [PDF]

Stroke, 2007
Induced hypothermia is one of the most promising neuroprotective therapies. Technological limitations and homeostatic mechanisms that maintain core body temperature have impeded the clinical use of hypothermia. Recent advances in intravascular cooling catheters and successful trials of hypothermia for cardiac arrest and neonatal asphyxia renewed ...
Thomas M, Hemmen, Patrick D, Lyden
openaire   +2 more sources