Results 51 to 60 of about 6,610,380 (222)
Hyperbilirubinemia exaggerates endotoxin-induced hypothermia [PDF]
Cell Cycle, 2015 Systemic inflammation is accompanied by an increased production of reactive oxygen species (ROS) and by either fever or hypothermia (or both). To study aseptic systemic inflammation, it is often induced in rats by the intravenous administration of bacterial lipopolysaccharide (LPS).
Pakai, Eszter +4 more
openaire +3 more sources
Facts and Fiction: The Impact of Hypothermia on Molecular Mechanisms following Major Challenge
Mediators of Inflammation, 2012 Numerous multiple trauma and surgical patients suffer from accidental hypothermia. While induced hypothermia is commonly used in elective cardiac surgery due to its protective effects, accidental hypothermia is associated with increased posttraumatic ...
Michael Frink +4 more
doaj +1 more source
Neuroprotection by Therapeutic Hypothermia
Frontiers in Neuroscience, 2019 Hypothermia therapy is an old and important method of neuroprotection. Until now, many neurological diseases such as stroke, traumatic brain injury, intracranial pressure elevation, subarachnoid hemorrhage, spinal cord injury, hepatic encephalopathy, and
Ying-Jian Sun +3 more
doaj +1 more source
Enhanced sensitivity of postsynaptic serotonin-1A receptors in rats and mice with high trait aggression [PDF]
, 2001 Individual differences in aggressive behaviour have been linked to variability in central serotonergic activity, both in humans and animals. A previous experiment in mice, selectively bred for high or low levels of aggression, showed an up-regulation of ...
Boer, Sietse F. de, +5 more
core +1 more source
Hypothermia-Induced Thrombocytopenia [PDF]
Journal of the Royal Society of Medicine, 1988 M A, Vella +3 more
+9 more sources
Comparison between Gel Pad Cooling Device and Water Blanket during Target Temperature Management in Cardiac Arrest Patients [PDF]
Acute and Critical Care, 2018 Background: Target temperature management (TTM) improves neurological outcomes for comatose survivors of out-of-hospital cardiac arrest. We compared the efficacy and safety of a gel pad cooling device (GP) and a water blanket (WB) during TTM. Methods: We
Yoon Sun Jung +3 more
doaj +1 more source
Effect of hypothermia on haemostasis and bleeding risk: a narrative review
Journal of International Medical Research, 2019 It must be remembered that clinically important haemostasis occurs in vivo and not in a tube, and that variables such as the number of bleeding events and bleeding volume are more robust measures of bleeding risk than the results of analyses.
Thomas Kander, Ulf Schött
doaj +1 more source
Preclinical discovery of duloxetine for the treatment of depression [PDF]
, 2012 Introduction: Affective disorders, including major depressive disorder (MDD), are among the most severely disabling mental disorders, and in many cases areIntroduction: Affective disorders, including major depressive disorder (MDD), are among the most ...
Berrocoso Domínguez, Esther María +4 more
core +2 more sources
Frontiers in Oncology, 2017 Background Peripheral neuropathy (PN) due to paclitaxel is a common dose-limiting toxicity with no effective prevention or treatment. We hypothesize that continuous-flow limb hypothermia can reduce paclitaxel-induced PN.
R. Sundar +17 more
semanticscholar +1 more source
PD149163 induces hypothermia to protect against brain injury in acute cerebral ischemic rats
Journal of Pharmacological Sciences, 2017 Therapeutic hypothermia is a promising strategy for acute cerebral ischemia via physical or pharmacological methods. In this study, we pharmacologically induced hypothermia on Sprague Dawley rats by intraperitoneally injecting PD149163.
Teng-Fei Xue +7 more
doaj +1 more source