Results 21 to 30 of about 92,945 (337)
Frontiers in Microbiology, 2021 Since hyperthermophilic Archaea (HA) thrive in high-temperature environments, which accelerate the rates of deamination of base in DNA, their genomic stability is facing a severe challenge.
Tan Lin +6 more
doaj +1 more source
Biosensor measurement of purine release from cerebellar cultures and slices [PDF]
, 2010 We have previously described an action-potential and Ca2+-dependent form of adenosine release in the molecular layer of cerebellar slices. The most likely source of the adenosine is the parallel fibres, the axons of granule cells. Using microelectrode
Dale, Nicholas +2 more
core +3 more sources
The Metabolomic Profile of Lymphoma Subtypes: A Pilot Study
Molecules, 2019 Lymphoma defines a group of different diseases. This study examined pre-treatment plasma samples from 66 adult patients (aged 20−74) newly diagnosed with any lymphoma subtype, and 96 frequency matched population controls. We used gas chromatography-
Luigi Barberini +7 more
doaj +1 more source
Frontiers in Oncology, 2021 BackgroundOral squamous cell carcinoma (OSCC) is the most malignant neoplasm in oral cancer. There is growing evidence that its progression involves altered metabolism.
Lihua Zuo +9 more
doaj +1 more source
Uptake of purines in Plasmodium falciparum-infected human erythrocytes is mostly mediated by the human Equilibrative Nucleoside Transporter and the human Facilitative Nucleobase Transporter [PDF]
, 2010 <b>Background</b>: Plasmodium parasites are unable to synthesize purines de novo and have to salvage them from the host. Due to this limitation in the parasite, purine transporters have been an area of focus in the search for anti-malarial ...
De Koning, H.P. +2 more
core +4 more sources
Metabolites, 2019 High-intensity interval training (HIIT) is known to improve performance and skeletal muscle energy metabolism. However, whether the body’s adaptation to an exhausting short-term HIIT is reflected in the resting human metabolome has not been ...
Sina Kistner +5 more
doaj +1 more source
Study on the diagnosis of gout with xanthine and hypoxanthine
Journal of clinical laboratory analysis (Print), 2019 Hyperuricemia is the only biochemical index in the classification of acute gouty arthritis in American Rheumatism Association 1977 and the main basis of clinical diagnosis for most doctors.
Yu Wang +5 more
semanticscholar +1 more source
Fatty Acid Oxidation and Meiotic Resumption in Mouse Oocytes [PDF]
, 2009 We have examined the potential role of fatty acid oxidation (FAO) in AMP-activated protein kinase (AMPK)-induced meiotic maturation. Etomoxir and malonyl CoA, two inhibitors of carnitine palmitoyl transferase-1 (CPT1), and thus FAO, blocked meiotic ...
Downs, Stephen +2 more
core +2 more sources
Adeno‐associated virus serotype 2 capsid variants for improved liver‐directed gene therapy
Hepatology, EarlyView., 2022 Abstract Background and Aims Current liver‐directed gene therapies look for adeno‐associated virus (AAV) vectors with improved efficacy. With this background, capsid engineering is explored. Whereas shuffled capsid library screenings have resulted in potent liver targeting variants with one first vector in human clinical trials, modifying natural ...
Nadja Meumann +25 more
wiley +1 more source
Shipin gongye ke-ji, 2022 Among many plant polysaccharides, arabinogalactan had the best growth-promoting effect on Akkermansia muciniphila (Akk) model strain (DSM 22959). In order to further explore the influence of arabinogalactan on Akk metabolites, arabinogalactan was used as
Xirui FENG +7 more
doaj +1 more source