Results 51 to 60 of about 65,592 (181)

Inherited/Genetically-Associated Pheochromocytoma/ Paraganglioma Syndromes and COVID-19

Medicina, 2021
In some subjects with inherited pheochromocytoma/paraganglioma (PPG) syndromes, hypoxia-inducible factor 1 alpha (HIF1α) stabilization/activation could lead to an increase in angiotensin converting enzymes (ACE).
Ioannis Ilias, Gregory Kaltsas, Konstantinos Barkas, George P. Chrousos   +3 more
doaj   +1 more source

Vascular Growth in the Fetal Lung [PDF]

, 2011
The structure of the lung is truly remarkable. It is primarily composed of three branched tubular networks (the airway, pulmonary artery and vein, bronchial artery and vein) which supply blood and air to the site of gas exchange and which maintain ...
Land, Stephen
core   +4 more sources

Complex coordination of cell plasticity by a PGC-1α-controlled transcriptional network in skeletal muscle [PDF]

, 2015
Skeletal muscle cells exhibit an enormous plastic capacity in order to adapt to external stimuli. Even though our overall understanding of the molecular mechanisms that underlie phenotypic changes in skeletal muscle cells remains poor, several factors ...
Agrawal, Aitchison, Altschul, Andersson, Blows, Blows, Bonduriansky, Brooks, Chenoweth, Chenoweth, Chung, Connallon, Coyne, Dallerac, Darwin, Doerge, Eyre-Walker, Fang, Ferreira, Ferveur, Fiumera, Frentiu, Gibbs, Gosden, Haldane, Hereford, Hine, Hine, Hine, Howard, Howard, Johnston, Kennington, Kingsolver, Kistler, Labeur, Lande, Long, Magwire, Mousseau, Park, Rako, Reinhart, Ritchie, Roff, Rundle, Sall, Siller, Swanson, Wagner, Weeks, Wilkinson, Zhang   +52 more
core   +4 more sources

Genomic and proteomic profiling of responses to toxic metals in human lung cells. [PDF]

, 2003
Examining global effects of toxic metals on gene expression can be useful for elucidating patterns of biological response, discovering underlying mechanisms of toxicity, and identifying candidate metal-specific genetic markers of exposure and response ...
Andrew, Angeline S, Barchowsky, Aaron, Hamilton, Joshua W, Klei, Linda, O'Hara, Kimberley A, Soucy, Nicole V, Temple, Kaili A, Warren, Amy J   +7 more
core   +2 more sources

Musashi mediates translational repression of the Drosophila hypoxia inducible factor. [PDF]

, 2016
Adaptation to hypoxia depends on a conserved α/β heterodimeric transcription factor called Hypoxia Inducible Factor (HIF), whose α-subunit is regulated by oxygen through different concurrent mechanisms.
Acevedo, Julieta María, Bertolin, Agustina Paola, Blanco Obregón, Dalmiro Manuel, Gándara, Lautaro, Kanda, Hiroshi, Katz, Maximiliano Javier, Okano, Hideyuki, Pozzi, María Berta, Sorianello, Eleonora Mariana, Srebrow, Anabella, Wappner, Pablo, Yano, Masato   +11 more
core   +1 more source

The role of HIF-1α-VEGF pathway in bronchiolitis obliterans after lung transplantation

Journal of Cardiothoracic Surgery, 2019
Background Graft function may be affected if the organ is exposed to hypoxia. We hypothesized that bronchiolitis obliterans (BO) after lung transplantation is associated with hypoxia-inducible factor-1α (HIF-1α). This study compares the expression of HIF-
Haichao Xu, Abudumailamu Abuduwufuer, Wang Lv, Zhenyu Zhou, Yunhai Yang, Chong Zhang, Jian Hu   +6 more
doaj   +1 more source

MOESM1 of The association between hypoxia inducible factor 1 subunit alpha gene rs2057482 polymorphism and cancer risk: a meta-analysis

, 2019
Additional file 1: Table S1. Quality score assessment. Table S2. Sensitivity analyses for rs2057482 polymorphism and cancer susceptibility. Table S3. Sensitivity analyses for rs2057482 polymorphism and cancer susceptibility in Asian population. Table S4. MAFs of rs2057482 polymorphism in the populations from the 1000 Genomes Project Phase 3.
Wu, Li-Fang, Xu, Gui-Ping, Zhao, Qing, Zhou, Li-Jing, Wang, Ding, Chen, Wei-Xian   +5 more
openaire   +1 more source

Correlation between imaging and tissue biomarkers of hypoxia in squamous cell cancer of the head and neck

World Journal of Nuclear Medicine, 2021
The aim of this study was to correlate endogenous tissue biomarkers of hypoxia with quantitative imaging parameters derived from 18F-fluoro-misonidazole (F-MISO) and 18F-fluoro-deoxy-glucose (FDG) positron emission tomography/computed tomography (PET/CT)
Shreya Kunder, Abhishek Chatterjee, Subhakankha Manna, Manoj Mahimkar, Asawari Patil, Venkatesh Rangarajan, Ashwini Budrukkar, Sarbani Ghosh-Laskar, Jai Prakash Agarwal, Tejpal Gupta   +9 more
doaj   +1 more source

Downregulation of genes with a function in axon outgrowth and synapse formation in motor neurones of the VEGF(delta/delta) mouse model of amyotrophic lateral sclerosis [PDF]

, 2010
Background: Vascular endothelial growth factor (VEGF) is an endothelial cell mitogen that stimulates vasculogenesis. It has also been shown to act as a neurotrophic factor in vitro and in vivo.
Bender, F.L.P., Brockington, A., Carmeliet, P., Claes, F., Heath, P.R., Holden, H., Kasher, P., Lambrechts, D., Sendtner, M., Shaw, P.J.   +9 more
core   +4 more sources

EZH2, HIF-1, and their inhibitors: An overview on pediatric cancers [PDF]

, 2018
During the past decades, several discoveries have established the role of epigenetic modifications and cellularmicroenvironment in tumor growth and progression. One of the main representatives concerning epigenetic modification is the polycomb group (PcG)
Antonello Mai, Diana Bellavia, Elisabetta Ferretti, Elisabetta Ferretti, Giuseppe Battaglia, Marco Papale, Marco Tafani   +6 more
core   +2 more sources