Results 241 to 250 of about 649,237 (386)

Hypoxia-Inducible Factor 1-Alpha (HIF-1α) and Cancer: Mechanisms of Tumor Hypoxia and Therapeutic Targeting. [PDF]

Cureus
Basheeruddin M, Qausain S.
europepmc   +1 more source

Hypoxia-inducible factor 1 alpha protein increases without changes in mRNA during acute hypoxic exposure of the Gulf killifish, Fundulus grandis. [PDF]

Biol Open, 2023
Murphy TE, Harris JC, Rees BB.
europepmc   +1 more source

Histone Lactylation Antagonizes Senescence and Skeletal Muscle Aging by Modulating Aging‐Related Pathways

Advanced Science, EarlyView.
This study reveals histone lactylation as a metabolic‐epigenetic regulator countering cellular senescence and skeletal muscle aging. Reduced lactylation impairs cell cycle, DNA repair and proteostasis pathways, while exercise restores glycolytic activity and lactylation levels, preserving muscle function.
Fanju Meng, Jianuo He, Xuebin Zhang, Wencong Lyu, Ran Wei, Shiyi Wang, Zhehao Du, Haochen Wang, Jinlong Bi, Xueyang Hua, Chao Zhang, Yiting Guan, Guoliang Lyu, Xiao‐Li Tian, Lijun Zhang, Wenbing Xie, Wei Tao   +16 more
wiley   +1 more source

Hypoxia-Inducible Factor-1&agr; Expression in Macrophages Promotes Development of Atherosclerosis

Arteriosclerosis, Thrombosis and Vascular Biology, 2016
Annemarie Aarup, Tanja X Pedersen, N. Junker, C. Christoffersen, E. Bartels, Marie Madsen, C. H. Nielsen, L. Nielsen   +7 more
semanticscholar   +1 more source

Correlation Between Intravascular Platelet Aggregation in Tumors and Hypoxia-Inducible Factor 1 Alpha Expression in Epithelial Ovarian Cancer: Implications for Prognosis and Staging. [PDF]

Cancers (Basel)
Ryu JM, Jeong YY, Lee SJ, Choi YS.
europepmc   +1 more source

Susceptibility of renal fibrosis in diabetes: Role of hypoxia inducible factor-1. [PDF]

FASEB J, 2022
Mei S, Li L, Zhou X, Xue C, Livingston MJ, Wei Q, Dai B, Mao Z, Mei C, Dong Z.   +9 more
europepmc   +1 more source

Integrative Multi‐Omics and Routine Blood Analysis Using Deep Learning: Cost‐Effective Early Prediction of Chronic Disease Risks

Advanced Science, EarlyView.
Omicsformer, a deep learning model, integrates multi‐omics and routine blood data to accurately predict risks for nine chronic diseases, including cancer and cardiovascular conditions. Validated using large scale clinical data, it reveals early risk trajectories, advancing personalized medicine and offering a cost‐effective, community‐based solution ...
Zhibin Dong, Pei Li, Yi Jiang, Zhihan Wang, Shihui Fu, Hebin Che, Meng Liu, Xiaojing Zhao, Chunlei Liu, Chenghui Zhao, Qin Zhong, Chongyou Rao, Siwei Wang, Suyuan Liu, Dayu Hu, Dongjin Wang, Juntao Gao, Kai Guo, Xinwang Liu, En Zhu, Kunlun He   +20 more
wiley   +1 more source

Hypoxia-inducible factor-1 regulates lactase gene transcription in response to hypoxia in intestinal epithelial cells

, 2001
So Young Lee, Glenn T. Furuta, Sean P. Colgan, Ashima Madan, Eric Sibley   +4 more
openalex   +1 more source

Hypoxia-Inducible Factor 1-Alpha (HIF-1α): An Essential Regulator in Cellular Metabolic Control. [PDF]

Cureus
Basheeruddin M, Qausain S.
europepmc   +1 more source

The hypoxia-inducible factor 1 pathway plays a critical role in the development of breast muscle myopathies in broiler chickens: a comprehensive review. [PDF]

Front Physiol, 2023
Alnahhas N, Pouliot E, Saucier L.
europepmc   +1 more source