Results 41 to 50 of about 216,063 (137)

Kinin-B1 receptors in ischaemia-induced pancreatitis: Functional importance and cellular localisation [PDF]

open access: yes, 2003
In this study we compare the role of kininB1 and B2 receptors during ischaemia/reperfusion of rat pancreas. Our investigations were prompted by the observation that infusion of a kininB2 receptor antagonist produced significant improvement in acute ...
A. A. Roscher   +11 more
core   +1 more source

The paradox between resistance to hypoxia and liability to hypoxic damage in hyperglycemic peripheral nerves. Evidence for glycolysis involvement [PDF]

open access: yes, 1993
Isolated ventral and dorsal rat spinal roots incubated in normal (2.5 mM) or high glucose (25 mM) concentrations or in high concentrations of other hexoses were exposed transiently to hypoxia (30 min) in a solution of low buffering power.
Niedermeier, W.   +2 more
core   +1 more source

Intestinal oxygen utilisation and cellular adaptation during intestinal ischaemia–reperfusion injury

open access: yesClinical and Translational Medicine
The gastrointestinal tract can be deranged by ailments including sepsis, trauma and haemorrhage. Ischaemic injury provokes a common constellation of microscopic and macroscopic changes that, together with the paradoxical exacerbation of cellular ...
Paraschos Archontakis‐Barakakis   +7 more
doaj   +1 more source

Reactive Oxygen Species Formation in the Brain at Different Oxygen Levels: The Role of Hypoxia Inducible Factors

open access: yesFrontiers in Cell and Developmental Biology, 2018
Hypoxia inducible factor (HIF) is the master oxygen sensor within cells and is central to the regulation of cell responses to varying oxygen levels. HIF activation during hypoxia ensures optimum ATP production and cell integrity, and is associated both ...
Ruoli Chen   +8 more
doaj   +1 more source

Therapeutic modulation of liver ischaemia reperfusion injury [PDF]

open access: yes, 2011
Liver Ischaemia Reperfusion Injury (IRI) leads to production of reactive oxygen species and cytokines, which affects hepatocellular function following liver resection and transplantation.
Sheth, H.
core  

Changes in excitability and accommodation of human motor axons following brief periods of ischaemia. [PDF]

open access: yes, 1991
1. The mechanism of post-ischaemic ectopic impulse generation in nerve is not known, and previous measurements of excitability changes in human motor axons have appeared to conflict.
Reid, G.   +3 more
core   +1 more source

Central and peripheral determinants of fatigue in acute hypoxia [PDF]

open access: yes, 2011
This thesis was submitted for the degree of Docter of Philosophy and awarded by Brunel University on 24th March 2011.Fatigue is defined as an exercise-induced decrease in maximal voluntary force produced by a muscle. Fatigue may arise from central and/or
Goodall, Stuart
core   +6 more sources

Ticagrelor Prevents Endothelial Cell Apoptosis through the Adenosine Signalling Pathway in the Early Stages of Hypoxia

open access: yesBiomolecules, 2020
Background: Several studies have reported the beneficial effects of anti-platelet drugs in cardioprotection against ischaemia–reperfusion injuries.
Catherine Feliu   +7 more
doaj   +1 more source

The role of orexin A in the pathogenesis of ischaemic stroke at high altitude

open access: yesExperimental Physiology
Orexin offers protection against cerebral ischaemia–reperfusion injury, with high altitude playing a key role in modulating its expression. This study aimed to investigate the effect of high altitude on orexin expression and its pathophysiological ...
Minxia Zhu   +7 more
doaj   +1 more source

Anaesthetic management in endovascular total aortic arch repair via needle-based in situ fenestration: a case series of 14 patients

open access: yesJournal of International Medical Research, 2020
Objective Endovascular total aortic arch repair (ETAAR) via needle-based in situ fenestration (ISF) is a major challenge for anaesthesiologists because of haemodynamic instability and the risk of cerebral hypoxia.
Kui-Rong Wang   +3 more
doaj   +1 more source

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