Results 151 to 160 of about 1,949,320 (295)

Early enteral nutrition and neurodevelopment in very low birth weight preterm infants

Journal of Pediatric Gastroenterology and Nutrition, EarlyView.
Abstract Objective Very low birth weight (VLBW) preterm infants are at increased risk of neurodevelopmental impairment. Although human milk may promote brain development, the association between type of feeding at discharge and neurodevelopmental outcomes remains uncertain.
Serafina Perrone, Maria Maddalena Brambilla, Virginia Beretta, Sabrina Moretti, Vincenzo Raitano, Chiara Petrolini, Valentina Dell'Orto, Silvia Carloni   +7 more
wiley   +1 more source

From nature to nanoscale: advances, challenges, and preclinical translation of nanofiber drug delivery systems containing plant‐derived active ingredients

Journal of the Science of Food and Agriculture, EarlyView.
Abstract Since the early 1960s, nanotechnology has been a critical area of science, allowing for the development of sophisticated nanomaterials. Nanofibers, one of the most widely used nanotechnological drug delivery systems, have emerged as a highly versatile platform within modern pharmaceutical sciences.
Heybet Kerem Polat, Yasin Turanlı, Nihat Kurt, Sefa Gözcü, Emre Tunçel, Hilal Bacanak, Eren Aytekin, Sedat Ünal   +7 more
wiley   +1 more source

ZFP36L1 Enhances Microglial Ferroptosis in Ischemic Stroke by Reducing FTO‐Mediated N6‐Methyladenosine Demethylation of ACSL1 mRNA

The Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT Microglia play an important role in ischemic stroke (IS). However, the molecular regulatory mechanisms underlying microglial ferroptosis in IS remain incompletely understood. In this study, blood samples were collected from 20 IS patients and 15 healthy volunteers.
Ai‐Xia Song, Han‐Xu Jin, Yuan‐Xin Sun, Wen‐Hui Kou, Xiao‐Ning Niu, Huan‐Huan Wang, Ting‐Ting Zhong, Ping Gu   +7 more
wiley   +1 more source

Proteomics of Nitrotyrosine: Integrating Mass Spectrometry and Immunodetection in Redox‐Driven Pathology

Mass Spectrometry Reviews, EarlyView.
ABSTRACT Nitrooxidative stress, driven by excess reactive nitrogen species like peroxynitrite, contributes to the pathogenesis of many chronic diseases. Among its molecular footprints, 3‐nitrotyrosine (3NT) has emerged as a biologically relevant marker of protein nitration.
Brîndușa Alina Petre
wiley   +1 more source

Recent Advances in Exosome‐Based Nanodelivery Systems for Traumatic Brain Injury Treatment

Med Research, EarlyView.
An overview of functional modification, therapeutic effects, molecular composition, and delivery strategies for exosomes. ABSTRACT Traumatic brain injury (TBI) is a highly heterogeneous neurological condition with extremely high rates of mortality and disability.
Jue Zhu, Weiquan Liao, Ziqi Lian, Mengdan Zhang, Chenxing Wang, Xingjia Zhu, Lin Zhang, Jian Chen, Zhichao Lu, Peipei Gong   +9 more
wiley   +1 more source

Hypoxia-ischemia and retinal ganglion cell damage

, 2008
Charanjit Kaur1, Wallace S Foulds2, Eng-Ang Ling11Department of Anatomy, Yong Loo Lin School of Medicine, National University of Singapore, Singapore; 2Singapore Eye Research Institute, SingaporeAbstract: Retinal hypoxia is the potentially blinding ...
Eng-Ang Ling, Wallace S Foulds, Charanjit Kaur   +2 more
core  

Repurposing antimicrobial agents for neuroprotection: Mechanisms, clinical potential, and challenges

Neuroprotection, EarlyView.
Antimicrobial agents exert neuroprotective effects through modulation of interconnected pathways. Tetracyclines, macrolides, antimalarial agents, sulfones, and antiparasitic agents suppress neuroinflammation, oxidative stress, and apoptosis while preserving mitochondrial function and neurotransmission.
Mohammad Amin Manavi, Mohammadreza Salehi, Razieh Mohammad Jafari, Ramin Goudarzi, Saman Khosravi, Ahmad Reza Dehpour   +5 more
wiley   +1 more source

Extracellular Vesicle-Derived microRNA-410 From Mesenchymal Stem Cells Protects Against Neonatal Hypoxia-Ischemia Brain Damage Through an HDAC1-Dependent EGR2/Bcl2 Axis.

Front Cell Dev Biol, 2020
Han J, Yang S, Hao X, Zhang B, Zhang H, Xin C, Hao Y.   +6 more
europepmc   +1 more source

Nomogram integrating MRI radiomics and white matter hyperintensity grading for predicting overall survival in patients with non‐small cell lung cancer and brain metastases receiving whole‐brain radiotherapy

Precision Radiation Oncology, EarlyView.
A prognostic nomogram integrating radiomic features and white matter hyperintensity (WMH) grading was developed to enable individualized survival prediction in patients with brain metastases (BMs). Integration of these imaging biomarkers into the clinical model enhanced predictive performance, indicating their incremental prognostic value for BM ...
Jianan Ni, Yuefeng Lu, Haoli Xu, Xuni Xu, Mengjing Zhao, Yingnan Xue, Gang Li, Yuxia Duan   +7 more
wiley   +1 more source

KR-33028 attenuates ischemia/hypoxia-induced blood-brain barrier hyperpermeability through maintaining tight junction integrity

, 2012
We have previously demonstrated that KR-33028, a novel inhibitor of Na+/H+ exchanger-1(NHE-1), exerts neuroprotective effects during cerebral ischemia.
Park, Sung Lyea, Yoo, Sung Eun, Lee, Sunkyung, Yi, Kyu Yang, Lee, Dong Ha, Jung, Yi-Sook   +5 more
core   +1 more source