Results 21 to 30 of about 956,013 (356)
Vascular changes in the rat brain during chronic hypoxia in the presence and absence of hypercapnia. [PDF]
, 2005 Changes in brain vascularity in adult rats during adaptation to chronic normobaric hypoxia with or without elevated CO(2) were morphometrically investigated.
Hayashida, Yoshiaki +6 more
core +1 more source
Hypoxia in the Initiation and Progression of Neuroblastoma Tumours [PDF]
, 2020 Neuroblastoma is the most frequent extracranial solid tumour in children, causing 10% of all paediatric oncology deaths. It arises in the embryonic neural crest due to an uncontrolled behaviour of sympathetic nervous system progenitors, giving rise to ...
Gómez Muñoz, María Ángeles +3 more
core +1 more source
Hypoxia in Atherogenesis [PDF]
Angiology, 2016 The anoxemia theory proposes that an imbalance between the demand for and supply of oxygen in the arterial wall is a key factor in the development of atherosclerosis. There is now substantial evidence that there are regions within the atherosclerotic plaque in which profound hypoxia exists; this may fundamentally change the function, metabolism, and ...
Ferns, Gordon A A, Heikal, Lamia
openaire +2 more sources
The Somatotropic Axis in the Sleep Apnea-Obesity Comorbid Duo
Frontiers in Endocrinology, 2020 Background: Growth hormone (GH) stimulates the production of insulin-like growth factor 1 (IGF-1) in most tissues and together GH and IGF-1 profoundly impact adipose tissue deposition, glucose metabolism and cardiovascular function.
Louis-Marie Galerneau +8 more
doaj +1 more source
Frontiers in Oncology, 2022 Integrin α11β1 is a collagen-binding integrin that is needed to induce and maintain the myofibroblast phenotype in fibrotic tissues and during wound healing.
Guillermo A. Martínez-Nieto +20 more
doaj +1 more source
Intrapulmonary shunting and pulmonary gas exchange during normoxic and hypoxic exercise in healthy humans [PDF]
, 2008 Exercise-induced intrapulmonary arteriovenous shunting, as detected by saline contrast echocardiography, has been demonstrated in healthy humans. We have previously suggested that increases in both pulmonary pressures and blood flow associated with ...
Eldridge, MW +5 more
core +2 more sources
Pulmonary Circulation, 2020 In some subjects, high-altitude hypobaric hypoxia leads to high-altitude pulmonary hypertension. The threshold for the diagnosis of high-altitude pulmonary hypertension is a mean pulmonary artery pressure of 30 mmHg, even though for general pulmonary ...
Julio Brito +2 more
doaj +1 more source
Frontiers in Immunology, 2022 Chronic ethanol abuse is a systemic disorder and a risk factor for acute respiratory distress syndrome (ARDS) and chronic obstructive pulmonary disease (COPD). However, the mechanisms involved are unknown.
Wenhua Sang +6 more
doaj +1 more source
Inflammatory Hypoxia: Role of Hypoxia-Inducible Factor [PDF]
Cell Cycle, 2004 Sites of inflammation are characterized by significant changes in metabolic activity. Shifts in energy supply and demand can result in diminished delivery and/or availability of oxygen, leading to inflammation-associated tissue hypoxia and metabolic acidosis. These shifts in tissue metabolism, as indicated by previous studies, are frequently associated
Jörn, Karhausen +2 more
openaire +2 more sources
Altered Oxygen Utilisation in Rat Left Ventricle and Soleus after 14 Days, but Not 2 Days, of Environmental Hypoxia. [PDF]
, 2015 The effects of environmental hypoxia on cardiac and skeletal muscle metabolism are dependent on the duration and severity of hypoxic exposure, though factors which dictate the nature of the metabolic response to hypoxia are poorly understood.
Burgess, Sarah L. +3 more
core +5 more sources