Results 31 to 40 of about 1,127,805 (351)

The Influence of Body Size and Hemoglobin Multiplicity on Critical Oxygen Threshold in Red Drum (Sciaenops ocellatus) [PDF]

open access: yes, 2016
Hypoxia is common in marine environments and fishes use a suite of cardiorespiratory adjustments to defend aerobic metabolism, including reducing standard metabolic rate (SMR), the minimum metabolic rate needed to sustain life at a specified temperature,
Pan, Yihang
core   +1 more source

Vascular changes in the rat brain during chronic hypoxia in the presence and absence of hypercapnia. [PDF]

open access: yes, 2005
Changes in brain vascularity in adult rats during adaptation to chronic normobaric hypoxia with or without elevated CO(2) were morphometrically investigated.
Hayashida, Yoshiaki   +6 more
core   +1 more source

Hypoxia and Hypoxia-Inducible Factors in Leukemias [PDF]

open access: yesFrontiers in Oncology, 2016
Despite huge improvements in the treatment of leukemia, the percentage of patients suffering relapse still remains significant. Relapse most often results from a small number of leukemic stem cells (LSCs) within the bone marrow, which are able to self-renew, and therefore reestablish the full tumor.
Margaux eDeynoux   +4 more
openaire   +3 more sources

Metabolism of asymmetric dimethylarginine in hypoxia: from bench to bedside

open access: yesPulmonary Circulation, 2020
Acute hypoxia and chronic hypoxia induce pulmonary vasoconstriction. While hypoxic pulmonary vasoconstriction is a physiological response if parts of the lung are affected, global exposure to hypoxic conditions may lead to clinical conditions like high ...
Juliane Hannemann   +3 more
doaj   +1 more source

Hypoxia-inducible hydrogels [PDF]

open access: yesNature Communications, 2014
Oxygen is vital for the existence of all multicellular organisms, acting as a signalling molecule regulating cellular activities. Specifically, hypoxia, which occurs when the partial pressure of oxygen falls below 5%, plays a pivotal role during development, regeneration and cancer.
Park, Kyung Min, Gerecht, Sharon
openaire   +2 more sources

The Somatotropic Axis in the Sleep Apnea-Obesity Comorbid Duo

open access: yesFrontiers in Endocrinology, 2020
Background: Growth hormone (GH) stimulates the production of insulin-like growth factor 1 (IGF-1) in most tissues and together GH and IGF-1 profoundly impact adipose tissue deposition, glucose metabolism and cardiovascular function.
Louis-Marie Galerneau   +8 more
doaj   +1 more source

Intrapulmonary shunting and pulmonary gas exchange during normoxic and hypoxic exercise in healthy humans [PDF]

open access: yes, 2008
Exercise-induced intrapulmonary arteriovenous shunting, as detected by saline contrast echocardiography, has been demonstrated in healthy humans. We have previously suggested that increases in both pulmonary pressures and blood flow associated with ...
Eldridge, MW   +5 more
core   +2 more sources

HIF-1-mediated expression of pyruvate dehydrogenase kinase: a metabolic switch required for cellular adaptation to hypoxia.

open access: yesCell Metabolism, 2006
Activation of glycolytic genes by HIF-1 is considered critical for metabolic adaptation to hypoxia through increased conversion of glucose to pyruvate and subsequently to lactate.
Jung-whan Kim   +3 more
semanticscholar   +1 more source

Hypoxia and the Tumor Microenvironment

open access: yesTechnology in Cancer Research and Treatment, 2021
Hypoxia is an important feature of the tumor microenvironment, and is closely associated with cell proliferation, angiogenesis, metabolism and the tumor immune response.
Yue Li, Longtao Zhao, Xiao-Feng Li
semanticscholar   +1 more source

Hypoxia in Atherogenesis [PDF]

open access: yesAngiology, 2016
The anoxemia theory proposes that an imbalance between the demand for and supply of oxygen in the arterial wall is a key factor in the development of atherosclerosis. There is now substantial evidence that there are regions within the atherosclerotic plaque in which profound hypoxia exists; this may fundamentally change the function, metabolism, and ...
Ferns, Gordon A A, Heikal, Lamia
openaire   +2 more sources

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