Results 61 to 70 of about 3,320 (170)

Plasticization by PEG as a Strategy to Tune Surface Properties of Hypromellose Films at the Nano/Macroscale

Surfaces
Cellulose ether, like hypromellose (HM), is an extremely versatile material that is widely used in pharmaceutical products as film coatings. To modify the surface properties of HM films, additives are routinely included during the film formulation ...
Maurice Brogly, Sophie Bistac, Armand Fahs   +2 more
doaj   +1 more source

A study of compressibility and compactibility of directly compressible tableting materials containing tramadol hydrochloride

Acta Pharmaceutica, 2016
The paper evaluates and compares the compressibility and compactibility of directly compressible tableting materials for the preparation of hydrophilic gel matrix tablets containing tramadol hydrochloride and the coprocessed dry binders Prosolv® SMCC 90 ...
Mužíková Jitka, Kubíčková Alena
doaj   +1 more source

Sestrin2 Exerts a Novel Protective Effect Against LPS‐Induced Ferroptosis via the Nrf2–SLC7A11–GPX4 Signaling Axis

The FASEB Journal, Volume 39, Issue 22, 30 November 2025.
This graphical abstract shows that LPS downregulates SESN2, leading to suppressed GPX4 activity, increased ROS, lipid peroxidation, and inflammation. SESN2 overexpression reverses these effects by activating the Nrf2/SLC7A11/GPX4 axis, reducing MDA and 4HNE levels, preserving redox balance, and alleviating ocular symptoms including hypopyon and retinal
Xuerui Zhang, Jiawei Yin, Yuan Yang, Jie Peng, Yu Xu, Wenting Zhang, Haodong Xiao, Zupeng Lu, Huanyu Liu, Yanjun Wen, Miaomiao Liu, Enguang Chen, Xiang Zhang, Shipeng Guo, Lianhui Han, Huazhang Feng, Peiquan Zhao   +16 more
wiley   +1 more source

A Novel Semi‐Automated Pipeline for Optimizing 3D‐Printed Drug Formulations

Advanced Intelligent Systems, Volume 7, Issue 11, November 2025.
A novel, semi‐automated deep learning and differential evolution pipeline designed for generating medicines for 3D‐printed medicines is introduced. This pipeline successfully generates a diverse range of drug formulations with an 80% printing success rate and 92% accuracy in predicting printing parameters.
Youssef Abdalla, Martin Ferianc, Haya Alfassam, Atheer Awad, Ruochen Qiao, Miguel Rodrigues, Mine Orlu, Abdul W. Basit, David Shorthouse   +8 more
wiley   +1 more source

In Vitro Evaluation of Enteric-Coated HPMC Capsules—Effect of Formulation Factors on Product Performance

Pharmaceutics, 2020
A comparative study on different enteric-coated hard capsules was performed. The influence of different formulation factors like choice of enteric polymer, triethyl citrate (TEC) concentration (plasticizer), talc concentrations (anti-tacking agent), and ...
Maoqi Fu, Johannes Andreas Blechar, Andreas Sauer, Jozef Al-Gousous, Peter Langguth   +4 more
doaj   +1 more source

Efficacy and Safety of Artificial Tears Containing Lipidure and Hypromellose for the Treatment of Moderate Dry Eye Disease in Contact Lens Wearers

Medicina
Background and Objectives: Dry eye disease (DED) affects 5–50% of the global population and deeply influences everyday life activities. This study compared the efficacy, tolerability, and safety of novel Respilac artificial tears containing lipidure and ...
Caterina Gagliano, Marco Zeppieri, Antonio Longo, Giovanni Rubegni, Roberta Amato, Roberta Foti, Francesco Cappellani, Massimiliano Cocuzza, Federico Visalli, Ludovica Cannizzaro, Alessandro Avitabile, Giuseppe Gagliano, Lucia Lapenna, Fabiana D’Esposito   +13 more
doaj   +1 more source

Sustainable Shell Formulations as Alternative to the Conventional Soft Gelatin Capsules in Pharmaceutical and Nutraceutical Applications. A Review.

Macromolecular Materials and Engineering, Volume 310, Issue 8, August 2025.
In soft capsules (SCs), four crucial factors can modify the properties of the shell: the shell formulation, its interaction with the fill material, the SC production and its storage conditions. Gelatin is the most used gelling agent for SCs nowadays, but they have some drawbacks which can be solved including other alternative polymers in the shell ...
Francisco Javier Palomero‐Hernández, María Ángela Caballo‐González, Francisco Javier de la Mata, Sandra García‐Gallego   +3 more
wiley   +1 more source

Bio-Dis and the Paddle Dissolution Apparatuses Applied to the Release Characterization of Ketoprofen from Hypromellose Matrices

, 2009
The purposes of this work were: (1) to comparatively evaluate the effects of hypromellose viscosity grade and content on ketoprofen release from matrix tablets, using Bio-Dis and the paddle apparatuses, (2) to investigate the influence of the pH of the ...
PEZZINI, Bianca Ramos, FERRAZ, Humberto Gomes   +1 more
core   +1 more source

Preparation and characterization of a coacervate extended-release microparticulate delivery system for Lactobacillus rhamnosus

International Journal of Nanomedicine, 2011
Sk Md Athar Alli Department of Pharmaceutical Technology, Jadavpur University, Kolkata, West Bengal, IndiaBackground: The purpose of this study was to develop a mucoadhesive coacervate microparticulate system to deliver viable Lactobacillus rhamnosus ...
Alli SMA
doaj  

Compatibility and stability of valsartan in a solid pharmaceutical formulation

Brazilian Journal of Pharmaceutical Sciences, 2013
Valsartan (VAL) is a highly selective blocker of the angiotensin II receptor that has been widely used in the treatment of hypertension. Active pharmaceutical ingredient compatibility with excipients (crospovidone, hypromellose, magnesium stearate ...
Tamíris Amanda Júlio, Igor Fernando Zâmara, Jerusa Simone Garcia, Marcello Garcia Trevisan   +3 more
doaj   +1 more source