Results 81 to 90 of about 3,320 (170)

Influence of solvent mixtures on HPMCAS-celecoxib microparticles prepared by electrospraying

Asian Journal of Pharmaceutical Sciences, 2018
Hypromellose acetate succinate (HPMCAS) microparticles containing the poorly-water soluble drug celecoxib (CEL) were prepared by electrospraying intended for oral drug delivery.
Adam Bohr, Yingya Wang, Moritz Beck-Broichsitter, Mingshi Yang   +3 more
doaj   +1 more source

Utilization of the Drug–Polymer Solid Dispersion Obtained by Ball Milling as a Taste Masking Method in the Development of Orodispersible Minitablets with Hydrocortisone in Pediatric Doses

Pharmaceutics
The objective of the conducted research was to design 2 mm orodispersible minitablets of pediatric doses of hydrocortisone (0.5 mg; 1.0 mg) with desirable pharmaceutical properties and eliminate the sensation of a bitter taste using preparation of solid ...
Monika Trofimiuk, Katarzyna Olechno, Emil Trofimiuk, Anna Czajkowska-Kośnik, Patrycja Ciosek-Skibińska, Klaudia Głowacz, Joanna Lenik, Anna Basa, Halina Car, Katarzyna Winnicka   +9 more
doaj   +1 more source

Tribo-electrification and Powder Adhesion Studies in the Development of Polymeric Hydrophilic Drug Matrices

, 2015
The generation of tribo-electric charge during pharmaceutical powder processing can cause a range of complications, including segregation of components leading to content uniformity and particle surface adhesion.
Conway, Barbara R, Enes Šupuk, Muhammad Ghori, Šupuk, Enes, Conway, Barbara R., Barbara Conway, Ghori, Muhammad U.   +6 more
core   +1 more source

Investigation on the aerosol performance of dry powder inhalation hypromellose capsules with different lubricant levels [PDF]

, 2015
HPMC capsules are made by a dipping process and a surface lubricant for the mould pins is an essential processing aid for removing dried capsules shells. For the purpose of this study, the level was determined by quantifying methyloleate (MO) a component
Saleem, IY, Diez, F, Jones, BE, Diez, F., Jones, B.E., Polo, L., Kayali, N, Polo, L, Kayali, N., Saleem, I.Y.   +9 more
core   +1 more source

Formulation and evaluation of melatonin as fast dissolving oral strips using combined polymers

Zanco Journal of Medical Sciences
Background and objective: Fast-dissolving oral thin film (FDOF) is a novel and most advanced form of solid dosage form that dissolves or disintegrates in 1 minute when put in the mouth without water or chewing.
Muhannad Omer Taher, Huner Kamal Gardy
doaj   +1 more source

A study of the compaction process and the properties of tablets containing hypromellose and α-lactose monohydrate.

, 2014
Charles University in Prague Faculty of Pharmacy in Hradec Králové Department of Pharmaceutical Technology Student: Šárka Hávová Supervisor: PharmDr. Jitka Mužíková, Ph.D.
Hávová, Šárka
core  

USE OF HYPROMELLOSE AND HYDROXYPROPYL CELLULOSE TO DEVELOP AN AGE APPROPRIATE PLATFORM TECHNOLOGY FOR THE ADMINISTRATION OF MEDICINES TO CHILDREN

There is a significant need for research and development into paediatric medicines. The absence of suitable medicines or critical safety and efficacy information, poses significant risks to a particularly vulnerable patient population.
Ernest, T
core   +1 more source

Developing Composition and Technology of Ethylthiobenzimidazole Fumarate Matrix Tablets According to Specified Release Profile

Регуляторные исследования и экспертиза лекарственных средств
INTRODUCTION. Ethylthiobenzimidazole fumarate (ETBIF) is a new actoprotector and adaptogenic active pharmaceutical ingredient (API). ETBIF was found to be effective given in short intervals; side effects related to ETBIF stomach solubility are known ...
I. D. Kasymov, A. L. Marchenko, A. V. Basevich   +2 more
doaj   +1 more source

Submicrometric hypromellose acetate succinate particles as carrier for soy isoflavones extract with improved skin penetration performance

, 2017
In this study, hypromellose acetate succinate (HPMCAS) stable submicronic particles loaded with a soy isoflavones extract have been obtained by nano spray drying technology.
SANSONE, Francesca, Rita Patrizia Aquino, GASPARRI, FRANCO, Franco Gasparri, Rosalia Rodriguez Dorado, RUSSO, Paola, Pasquale Del Gaudio, RODRIGUEZ DORADO, ROSALIA, MENCHERINI, Teresa, DEL GAUDIO, Pasquale, Teresa Mencherini, Francesca Sansone, Paola Russo, AQUINO, Rita Patrizia   +13 more
core   +1 more source

Hypromellose in pharmaceutical technology of capsules and other medicinal product dosage forms

, 2011
Hypromellose – hydroxypropyl methylcellulose (HPMC) – is a semisynthetic polymer produced by chemical modification of the naturally occurring cellulose.
Pachecka, Jan, Tomaszewski, Piotr, Kubiak-Tomaszewska, Grażyna   +2 more
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