Results 11 to 20 of about 661,093 (139)

NMR Spectroscopy Study of the Effect of the Molecular Mass of Hypromellose Phthalate on Its Solubility [PDF]

, 2023
Scientific relevance. Hypromellose phthalate is used in enteric coatings for oral medicinal products. The proportion of phthalate groups in the polymer is standardised because it has a significant effect on solubility.
N. D. Bunyatyan, N. E. Kuz’mina, S. V. Moiseev, E. Yu. Severinova, V. A. Evteev   +4 more
core   +1 more source

NMR spectroscopy study of the structure of hypromellose phthalate, a component of enteric coatings of medicinal products [PDF]

, 2023
Scientific relevance. Hypromellose phthalate is a component of enteric coatings used to modify active substance release from oral medicinal products in the small intestine.
N. E. Kuz’mina, S. V. Moiseev, E. Yu. Severinova, V. V. Kosenko, V. A. Evteev   +4 more
core   +1 more source

Hypromellose improves mydriasis dynamics by phenylephrine in a rabbit experimental model

, 2023
Purpose: to determine the main characteristics of the mydriatic effect of drug formulations of phenylephrine, containing and not containing hypromellose, hyaluronic acid as an auxiliary component, in a comparative in vivo study, as well as to study their
G. K. Poluosmak, E. A. Litvin, D. S. Blinov, O. V. Vasilkina, E. V. Blinova, M. V. Shiсh, E. V. Shich, O. S. Vavilova   +7 more
core   +1 more source

Clinical and experimental rationale for using phenylephrine with hypromellose for the treatment of extra accommodation strain in patients with myopia [PDF]

, 2023
M.V. Makhova1, E.V. Shikh2, V.V. Strakhov1, D.S. Blinov3,4, G.K. Poluosmak2, E.V. Semeleva5, E.V. Blinova2,4 1Yaroslavl State Medical University, Yaroslavl, Russian Federation 2I.M.
D.S. Blinov, E.V. Semeleva, E.V. Blinova, E.V. Shikh, G.K. Poluosmak, M.V. Makhova, V.V. Strakhov   +6 more
core   +1 more source

A randomised controlled study of the efficacy of hypromellose and Lacri-Lube combination versus polyethylene/Cling wrap to prevent corneal epithelial breakdown in the semiconscious intensive care patient [PDF]

, 2004
Objective. To compare the efficacy of two forms of eye care (hypromellose and Lacri-Lube combination vs polyethylene/Cling wrap covers) for intensive care patients. Design. Randomised-controlled trial. Setting.
Thomas, Peter, Koroloff, Natasha, Coyer, Fiona, Coyer, Fiona M., Thomas, P, Boots, Robert, Coyer, F, Rickard, C, Koroloff, N, Rickard, Claire, Lipman, Jeff, Boots, R, Lipman, J   +12 more
core   +1 more source

Solid Dispersions as a Tool for Innovation in the Food Industry: A Path From Pharma to Food. [PDF]

J Food Sci
ABSTRACT Solid dispersion (SD) is a technique used to improve the solubility of poorly water‐soluble compounds by dispersing them in a solid water‐friendly carrier. Current trends indicate that natural‐based alternatives are increasingly replacing synthetic carriers, benefiting the pharmaceutical industry, where they were first adopted, and paving the ...
Rezende SC, Santamaria-Echart A, Dias MM, Barreiro MF.   +3 more
europepmc   +2 more sources

Dynamic mechanical thermal analysis of hypromellose 2910 free films [PDF]

, 2011
It is common practice to coat oral solid dosage forms with polymeric materials for controlled release purposes or for practical and aesthetic reasons. Good knowledge of thermo-mechanical film properties or their variation as a function of polymer grade ...
CASETTARI, LUCA, BONACUCINA, Giulia, Giovanna Mencarelli, G. Bonacucina, G. F. Palmieri, Marco Cespi, Giovanni Filippo Palmieri, G. Mencarelli, Giulia Bonacucina, Luca Casettari, L. Casettari, PALMIERI, Giovanni Filippo, M. Cespi, CESPI, MARCO   +13 more
core   +1 more source

Evaluation of methoxy polyethylene glycol-polylactide diblock copolymers as additive in hypromellose film coating [PDF]

, 2013
This paper deals with a new application of diblock methoxy polyethylene glycol-polylactide block copolymers, a class of synthetic biomaterials largely studied in the pharmaceutical and biomedical fields owing to their favorable properties such as ...
G. Giorgioni, PERINELLI, DIEGO ROMANO, D. R. Perinelli, CASETTARI, LUCA, BONACUCINA, Giulia, Luca Casettari, G. Bonacucina, G. F. Palmieri, GIORGIONI, Gianfabio, PALMIERI, Giovanni Filippo, M. Cespi, CESPI, MARCO   +11 more
core   +1 more source

Techniques for subretinal injections in animals

Veterinary Ophthalmology, Volume 28, Issue 2, Page 506-518, March 2025.
Abstract Subretinal injections are not commonly performed during clinical treatment of animals but are frequently used in laboratory animal models to assess therapeutic efficacy and safety of gene and cell therapy products. Veterinary ophthalmologists are often employed to perform the injections in the laboratory animal setting, due to knowledge of ...
Ryan F. Boyd, Simon M. Petersen‐Jones
wiley   +1 more source

First‐In‐Human Study of Mirogabalin (BM2216) Sustained‐Release Tablets: Safety, Tolerability, Pharmacokinetics, Food Effect and Dose Proportionality With Comparison to Mirogabalin Besylate in Healthy Participants

Diabetes, Obesity and Metabolism, Volume 28, Issue 11, Page 10795-10813, November 2026.
ABSTRACT Aim To characterise the pharmacokinetics (PKs) and safety of BM2216 sustained‐release (SR) tablets after single‐dose oral administration under fasted/fed conditions in healthy participants, assess the effect of food and dose proportionality, and compare the single and multiple‐dose PK of BM2216 SR tablets with mirogabalin besylate tablets to ...
Peiyang Song, Hongtao Zhao, Mingxue Zhu, Lei Wan, Yuan Chen, Zhongping Li, Chengyong Tang   +6 more
wiley   +1 more source