Results 41 to 50 of about 160,408 (307)
The clinical relevance of the IBD-associated variation within the risk gene locus encoding protein tyrosine phosphatase non-receptor type 2 in patients of the Swiss IBD cohort [PDF]
BACKGROUND/AIMS The single nucleotide polymorphism (SNP) rs1893217 within the gene locus encoding protein tyrosine phosphatase non-receptor type 2 (PTPN2) results in a dysfunctional PTPN2 protein is associated with Crohn's disease (CD) and exists in ...
Rogler, Gerhard +36 more
core +1 more source
Widely differing screening and treatment practice for osteoporosis in patients with inflammatory bowel diseases in the Swiss IBD cohort study [PDF]
Low bone mineral density (BMD) and osteoporosis remain frequent problems in patients with inflammatory bowel diseases (IBDs). Several guidelines with nonidentical recommendations exist and there is no general agreement regarding the optimal approach for ...
Rogler, Gerhard +36 more
core +1 more source
Acetic acid is one of the important weak acids which had long history in chemical industries. This weak organic acid has been widely used as one of the key intermediate for many chemical, detergent, wood and food industries.
Hassan M. Awad +5 more
doaj +1 more source
IBD-SAIRAUKSIA SAIRASTAVIEN NUORTEN SITOUTUMINEN LÄÄKEHOITOON [PDF]
IBD:tä, eli tulehduksellisia suolistosairauksia sairastaa Suomessa noin 50 000 ihmistä ja vuosittain jopa 2000 suomalaista saa joko Crohnin taudin tai colitis ulcerosa -diagnoosin.
Turunen, Elisa
core
Extraintestinal association in IBD
Inflammatory bowel diseases are a type of systemic disease that affects not only the gastrointestinal tract but also the extraintestinal organs in many people, which are known as extraintestinal manifestations (EIMs) of IBD and may have a major impact on
Ibrahim, Bishoy
core
An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes
GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg +14 more
wiley +1 more source
Distinguishing Crohn’s Disease From Non–Crohn’s Ileitis: A Gut Microbiome–Based Approach
Conclusion: The gut microbiome is unique in NCI and can be differentiated from Crohn’s by a novel bacterial profile. This study provides preliminary leads to help stratify patients who require active treatment in lines of CD.
Nalini Raghunathan +7 more
doaj +1 more source
Structure‐forward targeting of claudins with synthetic binders
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley +1 more source
This paper evaluates possible relations between the clinical activity and the histopathological findings of the entire intestine in dogs with inflammatory bowel disease (IBD).
David Farray +4 more
doaj +1 more source
Challenges in IBD Research: Preclinical Human IBD Mechanisms [PDF]
Preclinical human IBD mechanisms is part of five focus areas of the Challenges in IBD research document, which also include environmental triggers, novel technologies, precision medicine and pragmatic clinical research. The Challenges in IBD research document provides a comprehensive overview of current gaps in inflammatory bowel diseases (IBD ...
Pizarro, Theresa T. +19 more
openaire +3 more sources

