Results 131 to 140 of about 2,333 (171)

Molecular characterization of infectious bursal disease virus (IBDV): Diversity of very virulent IBDV in Tanzania

Archives of Virology, 2007
Nucleotide sequences of the VP2 hypervariable region (VP2-HVR) of 14 infectious bursal disease viruses (IBDVs) isolated in Tanzania from 2001 to 2004 were determined. Phylogenetic analysis showed that the isolates diverged into two genotypes and belonged to the very virulent (VV) type.
C J, Kasanga, T, Yamaguchi, P N, Wambura, A D, Maeda-Machang'u, K, Ohya, H, Fukushi   +5 more
openaire   +2 more sources

gga-miR-454 suppresses infectious bursal disease virus (IBDV) replication via directly targeting IBDV genomic segment B and cellular Suppressors of Cytokine Signaling 6 (SOCS6)

Virus Research, 2018
MicroRNAs (miRNAs), as post-transcriptional regulators, play important roles in the process of viral infection through inhibiting virus replication or modulating host immune response. However, the role of miRNAs in host response against infectious bursal disease virus (IBDV) infection is still unclear.
Bin Wang, Yongqiang Wang
exaly   +3 more sources

Modified live infectious bursal disease virus (IBDV) vaccine delays infection of neonatal broiler chickens with variant IBDV compared to turkey herpesvirus (HVT)-IBDV vectored vaccine

Vaccine, 2017
Chickens are commonly processed around 35-45days of age in broiler chicken industry hence; diseases that occur at a young age are of paramount economic importance. Early age infection with infectious bursal disease virus (IBDV) results in long-lasting immunosuppression and profound economic losses.
Shanika, Kurukulasuriya, Khawaja Ashfaque, Ahmed, Davor, Ojkic, Thushari, Gunawardana, Kalhari, Goonewardene, Ashish, Gupta, Betty, Chow-Lockerbie, Shelly, Popowich, Philip, Willson, Suresh K, Tikoo, Susantha, Gomis   +10 more
openaire   +2 more sources

Protection of chickens, with or without maternal antibodies, against IBDV infection by a recombinant IBDV-VP2 protein

Vaccine, 2010
The use of avian herpesviruses (Marek's disease virus, MDV) as vectors to express the capsid protein of infectious bursal disease virus (IBDV) was well established, and its protection against IBDV challenge has been evaluated previously. However, there is little data about rMDV1 expressing the VP2 protein of IBDV protecting SPF and commercial chickens ...
Xuemei, Zhou, Decheng, Wang, Jinmao, Xiong, Peijun, Zhang, Yongqing, Li, Ruiping, She   +5 more
openaire   +2 more sources

Processing of Infectious Bursal Disease Virus (IBDV) Polyprotein and Self-Assembly of IBDV-Like Particles in Hi-5 Cells

Biotechnology Progress, 2006
The capsid of infectious bursal disease virus (IBDV), with a size of 60-65 nm, is formed by an initial processing of polyprotein (pVP2-VP4-VP3) by VP4, subsequent assemblage of pVP2 and VP3, and the maturation of VP2. In Sf9 cells, the processing of polyprotein expressed was restrained in the stage of VP2 maturation, leading to a limited production of ...
Meng-Shiou, Lee, Shyue-Ru, Doong, Su-Yuan, Lai, Jin-Yi, Ho, Min-Ying, Wang   +4 more
openaire   +2 more sources

MDA5 attenuate autophagy in chicken embryo fibroblasts infected with IBDV

British Poultry Science, 2021
1. The role of melanoma differentiation-associated protein 5 (MDA5) in infectious bursal disease virus (IBDV)-induced autophagy was studied in chicken embryos.2. Chicken embryo fibroblasts (CEF) were used as the research model and small interfering RNA (siRNA), western blot, indirect enzyme-linked immunosorbent assay (ELISA), real-time fluorescence ...
M, Yu, R, Li, M, Wan, J, Chen, X, Shen, G, Li, M, Ge, R, Zhang   +7 more
openaire   +2 more sources

Infectious Bursal Disease Virus (IBDV)

2019
Infectious bursal disease virus (IBDV) is one of the most important viral pathogens of chickens. This virus causes great economic losses to the poultry industry due to factors like high mortality rates and poor growth performance of the affected chickens.
Maged Gomaa Hemida, Abdullah I. A. Al-Mubarak, Adel M. Abdelaziz, Abdulazim M. Ibrahim   +3 more
openaire   +1 more source

Structure-dependent efficacy of infectious bursal disease virus (IBDV) recombinant vaccines

Vaccine, 2003
The immunogenicity and protective capability of several baculovirus-expressed infectious bursal disease virus (IBDV)-derived assemblies as VP2 capsids, VPX tubules and polyprotein (PP)-derived mixed structures, were tested. Four-week-old chickens were immunised subcutaneously with one dose of each particulate antigen.
Jose R Caston, J. Ignacio Casal
exaly   +5 more sources

Protective Efficacy of Intermediate and Intermediate Plus Infectious Bursal Disease Virus (IBDV) Vaccines Against Very Virulent IBDV in Commercial Broilers

Avian Diseases, 2005
The evolution of very virulent (vv) infectious bursal disease virus (IBDV) has led to significant economic losses in many poultry-producing areas. Despite vigorous vaccination strategies, IBDV has been difficult to control. The protective efficacy of IBDV vaccines is traditionally evaluated in specific pathogen-free (SPF) chickens.
S, Rautenschlein, Ch, Kraemer, J, Vanmarcke, E, Montiel   +3 more
openaire   +2 more sources

SRPK1 facilitates IBDV replication by phosphorylating VP1 at S48

International Journal of Biological Macromolecules
Infectious Bursal Disease Virus (IBDV), a double-stranded RNA virus of the Avibirnavirus genus, causes significant vaccine failures in immunocompromised young poultry. The VP1 protein of IBDV undergoes post-translational modifications that are critical for viral RNA transcription, genome replication, and overall viral proliferation.
Huansheng Wu
exaly   +3 more sources