Results 161 to 170 of about 4,176 (200)

Epidemiological characteristics of infectious bursal disease virus (IBDV) in China from 2023 to 2024: Mutated very virulent IBDV (mvvIBDV) is associated with atypical IBD

Poultry Science
Infectious bursal disease (IBD), caused by the infectious bursal disease virus (IBDV), threatens the global poultry industry with acute immunosuppression.
Jingzhe Han, Ziwen Wu, Runhang Liu
exaly   +2 more sources

Molecular characterization of reassortant infectious bursal disease virus (IBDV) strains of genogroup A3B1 detected in some areas of Britain between 2020 and 2021

Virology
Infectious bursal disease virus (IBDV) causes a major immunosuppressive disease of chickens. As part of ongoing epidemiological surveillance for IBDV, the hypervariable region (HVR) of the VP2 capsid gene encoded by segment A, and a region of the VP1 ...
Vishwanatha R. A. P. Reddy, Salik Nazki, Andrew Broadbent   +2 more
exaly   +2 more sources

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Modified live infectious bursal disease virus (IBDV) vaccine delays infection of neonatal broiler chickens with variant IBDV compared to turkey herpesvirus (HVT)-IBDV vectored vaccine

Vaccine, 2017
Chickens are commonly processed around 35-45days of age in broiler chicken industry hence; diseases that occur at a young age are of paramount economic importance. Early age infection with infectious bursal disease virus (IBDV) results in long-lasting immunosuppression and profound economic losses.
Shanika, Kurukulasuriya, Khawaja Ashfaque, Ahmed, Davor, Ojkic, Thushari, Gunawardana, Kalhari, Goonewardene, Ashish, Gupta, Betty, Chow-Lockerbie, Shelly, Popowich, Philip, Willson, Suresh K, Tikoo, Susantha, Gomis   +10 more
openaire   +2 more sources

Processing of Infectious Bursal Disease Virus (IBDV) Polyprotein and Self-Assembly of IBDV-Like Particles in Hi-5 Cells

Biotechnology Progress, 2006
The capsid of infectious bursal disease virus (IBDV), with a size of 60-65 nm, is formed by an initial processing of polyprotein (pVP2-VP4-VP3) by VP4, subsequent assemblage of pVP2 and VP3, and the maturation of VP2. In Sf9 cells, the processing of polyprotein expressed was restrained in the stage of VP2 maturation, leading to a limited production of ...
Meng-Shiou, Lee, Shyue-Ru, Doong, Su-Yuan, Lai, Jin-Yi, Ho, Min-Ying, Wang   +4 more
openaire   +2 more sources

MDA5 attenuate autophagy in chicken embryo fibroblasts infected with IBDV

British Poultry Science, 2021
1. The role of melanoma differentiation-associated protein 5 (MDA5) in infectious bursal disease virus (IBDV)-induced autophagy was studied in chicken embryos.2. Chicken embryo fibroblasts (CEF) were used as the research model and small interfering RNA (siRNA), western blot, indirect enzyme-linked immunosorbent assay (ELISA), real-time fluorescence ...
M, Yu, R, Li, M, Wan, J, Chen, X, Shen, G, Li, M, Ge, R, Zhang   +7 more
openaire   +2 more sources

Effects of IBDV infection on expression of chTLRs in chicken bursa

Microbial Pathogenesis, 2019
Infectious bursal disease virus (IBDV) is the etiological agent of a highly contagious and immunosuppressive disease that affects domestic chickens. Toll-like receptors (TLRs), a kind of pattern recognition receptors, help the host to detect invading pathogens.
Yan, Yu, Lingling, Cheng, Lili, Li, Yanhong, Zhang, Qiuxia, Wang, Changbo, Ou, Zhiyong, Xu, Yimin, Wang, Jinyou, Ma   +8 more
openaire   +2 more sources

Optineurin inhibits IBDV replication via interacting with VP1

Veterinary Microbiology
Avibirnavirus, specifically Infectious Bursal Disease Virus (IBDV), is a highly contagious pathogen that causes significant economic losses in the poultry industry. The polymerase protein VP1 of IBDV is critical to the viral life cycle, facilitating the synthesis of viral mRNA and the genome.
Huansheng Wu, Chongde Lai
exaly   +3 more sources

Determination of Optimum Formulation of a Novel Infectious Bursal Disease Virus (IBDV) Vaccine Constructed by Mixing Bursal Disease Antibody with IBDV

Avian Diseases, 1995
A novel vaccine against infectious bursal disease virus (IBDV) has been developed. The new vaccine was constructed by mixing bursal disease antibody (BDA) contained in whole antiserum with live IBDV before lyophilization. To establish various formulations of BDA and IBDV, several BDA doses between 5 units and 80 units of BDA/50 microliters were mixed ...
C E, Whitfill, E E, Haddad, C A, Ricks, J K, Skeeles, L A, Newberry, J N, Beasley, P D, Andrews, J A, Thoma, P S, Wakenell   +8 more
openaire   +2 more sources

Infectious Bursal Disease Virus (IBDV)

2019
Infectious bursal disease virus (IBDV) is one of the most important viral pathogens of chickens. This virus causes great economic losses to the poultry industry due to factors like high mortality rates and poor growth performance of the affected chickens.
Maged Gomaa Hemida, Abdullah I. A. Al-Mubarak, Adel M. Abdelaziz, Abdulazim M. Ibrahim   +3 more
openaire   +1 more source

SRPK1 facilitates IBDV replication by phosphorylating VP1 at S48

International Journal of Biological Macromolecules
Infectious Bursal Disease Virus (IBDV), a double-stranded RNA virus of the Avibirnavirus genus, causes significant vaccine failures in immunocompromised young poultry. The VP1 protein of IBDV undergoes post-translational modifications that are critical for viral RNA transcription, genome replication, and overall viral proliferation.
Huansheng Wu
exaly   +3 more sources