Results 161 to 170 of about 3,761 (205)

Genetic Insight into the Interaction of IBDV with Host—A Clue to the Development of Novel IBDV Vaccines

open access: yesInternational Journal of Molecular Sciences, 2023
Infectious bursal disease virus (IBDV) is an immunosuppressive pathogen causing enormous economic losses to the poultry industry across the globe. As a double-stranded RNA virus, IBDV undergoes genetic mutation or recombination in replication during circulation among flocks, leading to the generation and spread of variant or recombinant strains.
Yongqiang Wang, Shijun J Zheng, Kai Li
exaly   +4 more sources

IBDV particles packaged with only segment A dsRNA

open access: yesVirology, 2016
Multi-segmented dsRNA viruses have been suggested to utilize cis-acting elements in the plus-strand RNA to accomplish genomic RNA assortment during viral packaging. It is not clear if bi-segmented dsRNA birnavirus uses the same strategy. By applying a reverse genetic technique, we generated IBDV particles packaged with only segment A by co-transfection
Yung-Yi C Mosley   +2 more
exaly   +4 more sources

Molecular genotyping of the infectious bursal disease virus (IBDV) isolated from Broiler Flocks in Egypt

open access: yesInternational Journal of Veterinary Science and Medicine, 2014
Re-emergence of highly virulent forms of IBDV has been the cause of significant economic losses. In present study, 52 bursa samples were assayed using reverse transcriptase-polymerase chain reaction (RT-PCR) for IBDV targeting VP2 gene. Out of the tested
Hussein A Hussein
exaly   +4 more sources

A Single Vaccination of IBDV Subviral Particles Generated by Kluyveromyces marxianus Efficiently Protects Chickens against Novel Variant and Classical IBDV Strains [PDF]

open access: yesVaccines, 2021
Infectious bursal disease (IBD), caused by the infectious bursal disease virus (IBDV), is a highly contagious and immunosuppressive disease in chickens worldwide. The novel variant IBDV (nvIBDV) has been emerging in Chinese chicken farms since 2017, but there are no available vaccines that can provide effective protection.
Qiang Huang, Yao Yu, Jungang Zhou
exaly   +4 more sources

Cell culture-adapted IBDV uses endocytosis for entry in DF-1 chicken embryonic fibroblasts

open access: yesVirus Research, 2012
Although membrane perforation was suggested as the means of penetration mediated by IBDV, the cellular mechanism being hijacked to facilitate its entry is largely unknown.
Fanya Zeng, F C C Leung
exaly   +2 more sources

Efficacy of Single Dose Recombinant Herpesvirus of Turkey Infectious Bursal Disease Virus (IBDV) Vaccination Against a Variant IBDV Strain [PDF]

open access: yesAvian Diseases, 2009
The use of viral vectors for transgenic expression of immunogenic proteins is a current trend in the poultry industry. The objective of this work was to assess the protection against the variant E of infectious bursal disease virus (IBDV), conferred by day-one vaccination with a commercial recombinant herpesvirus of turkey (HVT) vaccine (VAXXITEK ...
P Villegas
exaly   +4 more sources

Pathotyping of IBDV

Avian Diseases, 2020
The pathotype of a given isolate of a pathogen is an important characteristic that could be included in the nomenclature of this isolate.
Y M, Saif, Oscar, Fletcher
openaire   +2 more sources

Generation of a novel attenuated IBDV vaccine strain by mutation of critical amino acids in IBDV VP5

Vaccine
Infectious bursal disease virus (IBDV) is an acute and highly infectious RNA virus known for its immunosuppressive capabilities, chiefly inflicting rapid damage to the bursa of Fabricius (BF) of chickens. Current clinical control of IBDV infection relies on vaccination.
Hui Gao, Shujun Zhang, Yongqiang Wang
exaly   +3 more sources

Molecular characterization of infectious bursal disease virus (IBDV): Diversity of very virulent IBDV in Tanzania

Archives of Virology, 2007
Nucleotide sequences of the VP2 hypervariable region (VP2-HVR) of 14 infectious bursal disease viruses (IBDVs) isolated in Tanzania from 2001 to 2004 were determined. Phylogenetic analysis showed that the isolates diverged into two genotypes and belonged to the very virulent (VV) type.
C J, Kasanga   +5 more
openaire   +2 more sources

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