Modeling Infectious Bursal Disease Virus (IBDV) Antigenic Drift In Vitro [PDF]
Viruses, 2022 Infectious bursal disease virus (IBDV) vaccines do not induce sterilizing immunity, and vaccinated birds can become infected with field strains. Vaccine-induced immune selection pressure drives the evolution of antigenic drift variants that accumulate ...
Amin S. Asfor +5 more
semanticscholar +6 more sources
From nasal to basal: single-cell sequencing of the bursa of Fabricius highlights the IBDV infection mechanism in chickens [PDF]
Cell & Bioscience, 2021 Background Chickens, important food animals and model organisms, are susceptible to many RNA viruses that invade via the nasal cavity. To determine the nasal entry site of the virus and clarify why avians are susceptible to RNA viruses, infectious bursal
Abid Ullah Shah +8 more
doaj +3 more sources
Host Combats IBDV Infection at Both Protein and RNA Levels
Viruses, 2022 Infectious bursal disease (IBD) is an acute, highly contagious, and immunosuppressive avian disease caused by infectious bursal disease virus (IBDV). In recent years, with the emergence of IBDV variants and recombinant strains, IBDV still threatens the ...
Shujun Zhang, Shijun Zheng
doaj +4 more sources
Susceptibility of mammalian cell line for isolation of IBDV from clinical samples [PDF]
Brazilian Journal of Poultry Science, 2004 Susceptibility of chicken embryo related cells (CER) to non-classical IBDV was compared with Vero cells for the same purpose. It was used 20 bursal samples collected from clinical cases of IBDV, positive by histopathological evaluation. After three times
SEL Silva +3 more
doaj +9 more sources
Enhancing MyD88 oligomerization is one important mechanism by which IBDV VP2 induces inflammatory response. [PDF]
PLoS PathogensThe inflammatory response is an essential component of innate immunity to defense against pathogens. Infectious bursal disease (IBD) is the most important immunosuppressive disease in chickens and is caused by the infectious bursal disease virus (IBDV ...
Mengmeng Huang +18 more
doaj +3 more sources
Chicken IL-17 as a potent adjuvant enhances IBDV VP2 DNA vaccine immunogenicity and protective efficacy [PDF]
Poultry ScienceInfectious bursal disease virus (IBDV) is an important immunosuppressive virus in chickens, which caused an acute and highly contagious infectious disease and resulted in considerable economic losses in the world poultry industry.
Jianlou Zhang +4 more
doaj +3 more sources
TMT-based quantitative proteomic analysis of IBDV-infected CEF cells reveals a favorable role of chicken IRF10 in IBDV replication via suppressing type-I interferon expression [PDF]
Poultry ScienceInfectious bursal disease (IBD) is an acute, highly contagious disease caused by infectious bursal disease virus (IBDV), causing huge economic losses to the poultry industry worldwide.
Shujun Zhang +7 more
doaj +3 more sources
International Journal of Molecular Sciences, 2023 Infectious bursal disease virus (IBDV) is an immunosuppressive pathogen causing enormous economic losses to the poultry industry across the globe. As a double-stranded RNA virus, IBDV undergoes genetic mutation or recombination in replication during ...
Hui Gao +3 more
semanticscholar +3 more sources
A Single Mutation of VP2 is Responsible for the Lethality and Antigenicity Differences between Novel Variant and Very Virulent IBDV Strains [PDF]
Transboundary and Emerging Diseases, 2023 Infectious bursal disease is an acute, immunosuppressive infectious disease in chickens caused by the infectious bursal disease virus (IBDV), which causes huge economic losses to the global poultry industry.
Nan Jiang +16 more
openalex +2 more sources
A Single Vaccination of IBDV Subviral Particles Generated by Kluyveromyces marxianus Efficiently Protects Chickens against Novel Variant and Classical IBDV Strains [PDF]
Vaccines, 2021 Infectious bursal disease (IBD), caused by the infectious bursal disease virus (IBDV), is a highly contagious and immunosuppressive disease in chickens worldwide.
Deqiang Yang +6 more
semanticscholar +4 more sources