Results 1 to 10 of about 3,761 (205)

Host Combats IBDV Infection at Both Protein and RNA Levels

Viruses, 2022
Infectious bursal disease (IBD) is an acute, highly contagious, and immunosuppressive avian disease caused by infectious bursal disease virus (IBDV). In recent years, with the emergence of IBDV variants and recombinant strains, IBDV still threatens the ...
Shujun Zhang, Shijun Zheng
doaj   +4 more sources

Susceptibility of mammalian cell line for isolation of IBDV from clinical samples [PDF]

Brazilian Journal of Poultry Science, 2004
Susceptibility of chicken embryo related cells (CER) to non-classical IBDV was compared with Vero cells for the same purpose. It was used 20 bursal samples collected from clinical cases of IBDV, positive by histopathological evaluation. After three times
SEL Silva, HL Ferreira, BA Carvalho, TC Cardoso   +3 more
doaj   +2 more sources

Development of a multiplex real-time qRT-PCR for discriminating the predominant epidemic variant IBDV and very virulent IBDV. [PDF]

Front Vet Sci
Infectious bursal disease (IBD) is an important immunosuppressive disease of chicken caused by infectious bursal disease virus (IBDV). At present, the newly emerging novel variant IBDV (varIBDV) and the persistently prevalent very virulent IBDV (vvIBDV ...
Wu Z, Yu H, Wang G, Ling D, Zhang Y, Liu R, Ke E, Wang S, Zhang Y, Liu Y, Cui H, Chen Y, Duan Y, Liu X, Gao Y, Qi X.   +15 more
europepmc   +4 more sources

Susceptibility of Gecko Cell Line for Cultivation and Adaptation of Infectious Bursal Disease Virus as an Experimental Vaccine. [PDF]

Vet Med Sci
First successful cultivation of IBDV on reptile‐derived Z1 cells yields high‐titre virus and induces immunity in chickens. This scalable, egg‐free platform offers a promising alternative for vaccine production, leveraging evolutionary kinship between reptiles and birds for next‐generation poultry disease control.
Dolatabad SA, Namavari M, Behbahan NGG.
europepmc   +2 more sources

Rapid Spread of Novel Infectious Bursal Disease Virus Variant (Genotype A2dB1b) in the Near East and Persian Gulf Regions: Molecular Surveillance and Phylodynamic Reconstruction. [PDF]

Transbound Emerg Dis
Infectious bursal disease virus (IBDV) is one of the most impactful pathogens of poultry, with disease manifestations ranging from acute forms to subclinical but immunosuppressive infections. This heterogeneity, accompanied by a significant antigenic variability, is sustained by high mutation rates and frequent reassortments between the two genome ...
Poletto F, Alam S, Cherfane A, Franzo G, Tucciarone CM, Cecchinato M, Legnardi M.   +6 more
europepmc   +2 more sources

Identification and pathogenicity of a natural reassortant between a very virulent serotype 1 infectious bursal disease virus (IBDV) and a serotype 2 IBDV

Virology, 2011
Infectious bursal disease virus (IBDV) causes an economically important, immunosuppressive disease in chickens. There are two serotypes of the virus that contain a bi-segmented double-stranded RNA genome. In December 2008, the first very virulent (vv)IBDV was identified in California, USA and in 2009 we isolated reassortant viruses in two different ...
Jackwood, Daral J., Sommer-Wagner, Susan E., Crossley, Beate M., Stoute, Simone T., Woolcock, Peter R., Charlton, Bruce R.   +5 more
openaire   +3 more sources

Development and Characterization of Monoclonal Antibodies Against VP3 Protein of Infectious Bursal Disease Virus. [PDF]

Transbound Emerg Dis
Infectious bursal disease virus (IBDV) causes an acute, highly contagious and immunosuppressive disease in 3–5‐week‐old chicken, called infectious bursal disease (IBD). Current vaccines targeting the hypervariable VP2 gene fail to provide cross‐protection against different IBDV strains, necessitating the development of novel diagnostic and preventive ...
Pan XY, Ren H, Zi MH, Fan JH, Ma YH, Shao HC, Liang ZS, Zhang Y, Han S, Zhang GP, Wan B, Lin W, He WR.   +12 more
europepmc   +2 more sources

Assessment of genetic, antigenic and pathotypic criteria for the characterization of IBDV strains

Avian Pathology, 2004
The aim of this work was the selection and comparison of representative infectious bursal disease virus (IBDV) strains. Nine strains of IBDV, isolated at different times and from different geographic regions of Europe and China, were characterized. Batches of all strains were prepared following standardized protocols and checked for the absence of ...
Zierenberg, K, Zhang, MF, Zhu, YP, Lim, BL, Morales, D, Eterradossi, N, Rivallan, G, Toquin, D, Raue, R, Müller, H, Chen, GC, Wang, X, Zheng, HJ, Wang, CQ, Van Den Berg, TP   +14 more
openaire   +5 more sources

Herpesvirus of Turkey Recombinant Viruses Expressing Infectious Bursal Disease Virus (IBDV) VP2 Immunogen Induce Protection against an IBDV Virulent Challenge in Chickens

Virology, 1995
Two recombinant herpesviruses of turkey (HVT) expressing the VP2 protein of infectious bursal disease virus (IBDV or Gumboro disease virus) have been constructed: vHVT001 and vHVT002. The VP2 open reading frame was inserted at the locus of the small subunit of ribonucleotide reductase gene (HSV-1 UL40 homolog) without any exogenous promoter in vHVT001 ...
Darteil, Raphaël, Bublot, Michel, Laplace, Eliane, Bouquet, Jean-François, Audonnet, Jean-Christophe, Rivière, Michel   +5 more
openaire   +3 more sources

Enhancing MyD88 oligomerization is one important mechanism by which IBDV VP2 induces inflammatory response.

PLoS Pathogens
The inflammatory response is an essential component of innate immunity to defense against pathogens. Infectious bursal disease (IBD) is the most important immunosuppressive disease in chickens and is caused by the infectious bursal disease virus (IBDV ...
Mengmeng Huang, Mengmeng Xu, Jingzhe Han, Erjing Ke, Xinxin Niu, Yulong Zhang, Guodong Wang, Hangbo Yu, Runhang Liu, Suyan Wang, Yongzhen Liu, Yuntong Chen, Jinze Han, Ziwen Wu, Hongyu Cui, Yanping Zhang, Yulu Duan, Yulong Gao, Xiaole Qi   +18 more
doaj   +2 more sources