Constitutively elevated levels of SOCS1 suppress innate responses in DF-1 immortalised chicken fibroblast cells. [PDF]
The spontaneously immortalised DF-1 cell line is rapidly replacing its progenitor primary chicken embryo fibroblasts (CEFs) for studies on avian viruses such as avian influenza but no comprehensive study has as yet been reported comparing their innate ...
A Tiwari+58 more
core +2 more sources
The H10 subtype avian influenza virus (AIV), an important zoonotic pathogen, is widely prevalent in host species (wild fowl) and continues to infect humans, imposing a huge threat to public health. Thus, the H10 subtype AIV is considered a potential pandemic strain and has drawn the attention of scholars worldwide.
Jiamin Fu+10 more
wiley +1 more source
Infectious bursal disease (IBD) is an acute and highly contagious immunosuppressive disease caused by the infectious bursal disease virus (IBDV), which seriously threatens the healthy development of the poultry industry.
Nan Jiang+15 more
doaj +1 more source
Development of Real-Time Polymerase Chain Reaction Assays for the Detection and Differentiation of Infectious Bursal Disease Virus Subtypes [PDF]
Two different real-time polymerase chain reaction (PCR) detection approaches based on SYBR Green I dye and Taqman probe based assays were developed for the detection and differentiation of infectious bursal disease virus (IBDV) subtypes.
Kong, Lih Ling
core
hnRNPs in antiviral innate immunity
We review the roles that heterogeneous nuclear ribonucleoproteins (hnRNPs) play in the modulation of host innate immunity in humans, mice and other animals, and reflect on the potential for leveraging of hnRNPs in antiviral therapies. Abstract During virus infection, many host proteins are redirected from their normal cellular roles to restrict and ...
Sofia Maceratessi, Natalia G. Sampaio
wiley +1 more source
Infectious bursal disease virus: identification of the novel genetic group and reassortant viruses
The results of the phylogenic analysis of the nucleotide sequence of the IBDV A and B genome segments have been presented. Traditionally the IBDV isolates are classified based on the phylogenic analysis of the hypervariable region of the VP2 gene.
L. O. Scherbakova+7 more
doaj +1 more source
Pathogenicity and Molecular Characterisation of the VP2 Gene of Infectious Bursal Disease Virus [PDF]
Pathogenicity of four infectious bursal disease virus (IBDV) isolates was studied on specific-pathogen-free (SPF) chickens. Chickens inoculated with isolates 92/04, 94/B551 and 97/61 developed severe clinical manifestations with a high mortality ranging ...
Mahfuzul Hoque, Md
core
Carbon‐Based Nanomaterials for Antiviral Applications
Carbon‐based nanomaterials (CBNs), including fullerenes, carbon dots, graphene, and their derivatives, show promise as antiviral tools in the antimicrobial resistance era. They exhibit broad‐spectrum antiviral activity with a low risk of resistance development. CBNs also enhance efficacy under light exposure and support antiviral immune responses. CBNs
Ángel Serrano‐Aroca+3 more
wiley +1 more source
Characterization and pathogenicity of infectious bursal disease virus in Southern China
: Infectious bursal disease virus (IBDV) is a widespread pathogen that induces immunosuppression in 3 to 6-wk-old chickens, casuing great threaten to the poultry industry worldwide.
Zixian Chen+5 more
doaj
The C-terminal domain of the pVP2 precursor is essential for the interaction between VP2 and VP3, the capsid polypeptides of infectious bursal disease virus [PDF]
The interaction between the infectious bursal disease virus (IBDV) capsid proteins VP2 and VP3 has been analyzed in vivo using baculovirus expression vectors.
Abaitua, Fernando+5 more
core +1 more source