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An IC 50 Calculator: brittalundstroem/IC50: IC50 R tool: Dominic; Marrnel
, 2023 An R Shiny App to calculate IC50 and confidence interval.
Ritler, Dominic +2 more
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Guidelines for accurate EC50/IC50 estimation
Pharmaceutical Statistics, 2011AbstractThis article provides minimum requirements for having confidence in the accuracy of EC50/IC50 estimates. Two definitions of EC50/IC50s are considered: relative and absolute. The relative EC50/IC50 is the parameter c in the 4‐parameter logistic model and is the concentration corresponding to a response midway between the estimates of the lower ...
exaly +3 more sources
Variations in IC50 Values with Purity of Mushroom Tyrosinase
International Journal of Molecular Sciences, 2009 The effects of various inhibitors on crude, commercial and partially purified commercial mushroom tyrosinase were examined by comparing IC50 values.
George Fritch +5 more
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DFT based Computational Methodology of IC50 Prediction
Current Computer-Aided Drug Design, 2021Background: IC 50 is one of the most important parameters of a drug. But, it is very difficult to predict this value of a new compound without experiment. There are only a few QSAR based methods available for IC 50
openaire +2 more sources