Results 111 to 120 of about 159,080 (332)
The Immunological Basis of Dry Eye Disease and Current Topical Treatment Options. [PDF]
, 2020 Homeostasis of the lacrimal functional unit is needed to ensure a well-regulated ocular immune response comprising innate and adaptive phases. When the ocular immune system is excessively stimulated and/or immunoregulatory mechanisms are disrupted, the ...
Lin, Meng C +4 more
core +1 more source
Confocal laser scanning microscope, raman microscopy and western blotting to evaluate inflammatory response after myocardial infarction [PDF]
, 2015 Cardiac muscle necrosis is associated with inflammatory cascade that clears the infarct from dead cells and matrix debris, and then replaces the damaged tissue with scar, through three overlapping phases: the inflammatory phase, the proliferative phase
Cantatore, S +6 more
core +1 more source
T Cell Exhaustion in Cancer Immunotherapy: Heterogeneity, Mechanisms, and Therapeutic Opportunities
Advanced Science, EarlyView.T cell exhaustion limits immunotherapy efficacy. This article delineates its progression from stem‐like to terminally exhausted states, governed by persistent antigen, transcription factors, epigenetics, and metabolism. It maps the exhaustion landscape in the TME and proposes integrated reversal strategies, providing a translational roadmap to overcome
Yang Yu +7 more
wiley +1 more source
Mediators of Inflammation, 2014 Intercellular adhesion molecule-1 (ICAM-1) is a key adhesion molecule mediating neutrophil migration and infiltration during sepsis. But its role in the outcome of sepsis remains contradictory.
Yan-jun Zhao +7 more
doaj +1 more source
Advanced Science, EarlyView.Tumor vascular remodeling is discussed from a chemokine‐centered perspective. This review summarizes the bidirectional, temporal, and tissue‐specific roles of CXC chemokines in regulating vascular function and immune accessibility. A functional vascular normalization score is introduced as a conceptual framework to integrate dynamic vascular and immune
Hongdan Chen +7 more
wiley +1 more source
The Predictive Value of Endothelial Inflammatory Markers in the Onset of Schizophrenia
Neuropsychiatric Disease and Treatment, 2020 Gabriela Radu,1,2,* Constantin Luca,3,* Lucian Petrescu,3,* Diana Aurora Bordejevic,2,3,* Mirela Cleopatra Tomescu,1,2 Minodora Andor,1,2 Ioana Cîtu,1,2 Adelina Mavrea,1,2 Valentina Buda,4 Cătălin Tomescu,1,2 Florin Borcan,4 Liana Dehelean5 ...
Radu G +11 more
doaj
Angiogenesis⁃ related factors expression in oral lichen planus
口腔疾病防治, 2017 Objective To detect the expression of vascular endothelial growth factor (VEGF), intercellular adhesion molecule⁃1 (ICAM⁃1), vascular cell adhesion molecule⁃1 (VCAM⁃1) in oral lichen planus (OLP).
LI Juxiong
doaj +1 more source
Advanced NanoBiomed Research, EarlyView.This review explains how biomaterials and nanoparticles can be used to induce or modulate tertiary lymphoid structures (TLSs), which are ectopic immune hubs that form in nonlymphoid tissues during chronic disease and cancer. By comparing different methods, the article highlights design principles for modeling TLSs or recapitulating specific TLS ...
Shaza Karaman, Mei ElGindi, Jeremy Teo
wiley +1 more source
Regulation of ICAM-1 in human neutrophils
Journal of Leukocyte BiologyAbstract Intercellular cell adhesion molecule 1 (ICAM-1) is a cell surface glycoprotein with a vital role in the immune response to pathogens. The expression pattern of ICAM-1 is wide ranging, encompassing endothelial cells, epithelial cells, and neutrophils. Recent work has characterized the role of ICAM-1 in murine neutrophils, but the
Vignarajah, Muralie +8 more
openaire +2 more sources
Membrane adhesion and domain formation
, 2007 We review theoretical results for the adhesion-induced phase behavior of biomembranes. The focus is on models in which the membranes are represented as discretized elastic sheets with embedded adhesion molecules. We present several mechanism that lead to
Lipowsky, Reinhard, Weikl, Thomas R.
core +1 more source