Role of liver ICAM-1 in metastasis
Oncology Letters, 2017 Intercellular adhesion molecule (ICAM)-1, is a transmembrane glycoprotein of the immunoglobulin (Ig)-like superfamily, consisting of five extracellular Ig-like domains, a transmembrane domain and a short cytoplasmic tail. ICAM-1 is expressed in various cell types, including endothelial cells and leukocytes, and is involved in several physiological ...
Aitor, Benedicto +2 more
openaire +4 more sources
ICAM-1–Related Noncoding RNA in Cancer Stem Cells Maintains ICAM-1 Expression in Hepatocellular Carcinoma [PDF]
Clinical Cancer Research, 2016 Abstract Purpose: Portal vein tumor thrombus (PVTT) is a major complication of hepatocellular carcinoma (HCC) and is associated with poor survival. Long noncoding RNAs (lncRNA) contribute to HCC metastasis, but whether and how lncRNAs affect PVTT development remains unclear.
Weixing, Guo +10 more
openaire +3 more sources
Role of ICAM-1 in triple-negative breast cancer [PDF]
Open MedicineIntercellular adhesion molecule-1 (ICAM-1) is related to the occurrence and development of a variety of tumors. However, the role of ICAM-1 in the regulation of growth, metastasis, and clinical prognosis of the specific molecular subtypes of breast ...
Zhang Ying +5 more
doaj +2 more sources
Neoplastic ICAM-1 protects lung carcinoma from apoptosis through ligation of fibrinogen [PDF]
Cell Death and DiseaseIntercellular cell adhesion molecule-1 (ICAM-1) is frequently overexpressed in non-small cell lung cancer (NSCLC) and associated with poor prognosis. However, the mechanism underlying the negative effects of neoplastic ICAM-1 remains obscure.
ShiHui Wang +9 more
doaj +2 more sources
T Cell Migration from Inflamed Skin to Draining Lymph Nodes Requires Intralymphatic Crawling Supported by ICAM-1/LFA-1 Interactions. [PDF]
Cell Reports, 2017 T cells are the most abundant cell type found in afferent lymph, but their migration through lymphatic vessels (LVs) remains poorly understood. Performing intravital microscopy in the murine skin, we imaged T cell migration through afferent LVs in vivo ...
Á. Teijeira +10 more
semanticscholar +5 more sources
Essential role of ICAM-1 in aldosterone-induced atherosclerosis. [PDF]
International Journal of Cardiology, 2017 OBJECTIVE: Elevated aldosterone is associated with increased risk of atherosclerosis complications, whereas treatment with mineralocorticoid receptor (MR) antagonists decreases the rate of cardiovascular events.
V. Marzolla +10 more
semanticscholar +3 more sources
Tumor site immune markers associated with risk for subsequent basal cell carcinomas. [PDF]
, 2011 BackgroundBasal cell carcinoma (BCC) tumors are the most common skin cancer and are highly immunogenic.ObjectiveThe goal of this study was to assess how immune-cell related gene expression in an initial BCC tumor biopsy was related to the appearance of ...
Andridge, Rebecca +13 more
core +17 more sources
ICAM-1-mediated adhesion is a prerequisite for exosome-induced T cell suppression.
Developmental Cell, 2022 Tumor-derived extracellular vesicles (TEVs) suppress the proliferation and cytotoxicity of CD8+ T cells, thereby contributing to tumor immune evasion. Here, we report that the adhesion molecule intercellular adhesion molecule 1 (ICAM-1) co-localizes with
Wei Zhang +19 more
semanticscholar +1 more source
Macrophage ICAM-1 functions as a regulator of phagocytosis in LPS induced endotoxemia
Inflammation Research, 2021 Intracellular adhesion molecule-1 (ICAM-1), a transmembrane glycoprotein belonging to the immunoglobulin superfamily, plays a critical role in mediating cell–cell interaction and outside-in cell signaling during the immune response.
Hanhui Zhong +7 more
semanticscholar +1 more source