Results 31 to 40 of about 27,302,336 (342)

An Anti-Human ICAM-1 Antibody Inhibits Rhinovirus-Induced Exacerbations of Lung Inflammation [PDF]

, 2013
Human rhinoviruses (HRV) cause the majority of common colds and acute exacerbations of asthma and chronic obstructive pulmonary disease (COPD). Effective therapies are urgently needed, but no licensed treatments or vaccines currently exist.
A Papi, A van de Stolpe, AC Palmenberg, Alan Carruthers, Alexandra Nikonova, Alison Humbles, AM Randi, Andrew J. Leishman, Andrew Pekosz, CR Uncapher, D Wat, DC Pevear, DE Staunton, DJ Jackson, DJ Jackson, DJ Jackson, FG Hayden, FG Hayden, Gary R. McLean, J Bizzintino, J Corren, J Garbino, J Las Heras, JE Gern, JE Prince, Jie Zhu, JM Greve, Katherine A. Vousden, Katie Bernard, KB Weiss, KG Nicholson, Leila Gogsadze, Matthew A. Sleeman, Michael Dymond, MS Diamond, Musa Khaitov, Nathan W. Bartlett, Nicholas Glanville, NW Bartlett, P Mallia, Q Wang, Qing Zhu, R Fleischer, Rebecca Dunmore, RF Lemanske Jr, RH Dougherty, RM Owens, Roland Kolbeck, Ross P. Walton, RR Turner, Sebastian L. Johnston, SK Lau, SL Binford, Stephanie Traub, Ted Wells, Weidong Hao, YA Bochkov   +56 more
core   +3 more sources

Characterization of rat lung ICAM-1 [PDF]

Inflammation Research, 1998
We expressed soluble rat ICAM-1, generated a polyclonal anti-ICAM-1 antibody, and studied ICAM-1 upregulation in lung inflammatory conditions. Bacterial and baculovirus expression systems were employed.250 g adult, male Long Evans rats were used. For in vitro studies, rat pulmonary artery endothelial cells (RPAEC), rat alveolar macrophages and aortic ...
Schimmer, R. C., Beck-Schimmer, B., Ward, Peter A., Friedl, Hans P., Flory, C. M., Schmal, H., Pasch, T.   +6 more
openaire   +3 more sources

Induction by IL 1 and interferon-gamma: tissue distribution, biochemistry, and function of a natural adherence molecule (ICAM-1).

Journal of Immunology, 1986
ICAM-1 is a cell surface glycoprotein originally defined by a monoclonal antibody (MAb) that inhibits phorbol ester-stimulated leukocyte aggregation. Staining of frozen sections and immunofluorescence flow cytometry showed intercellular adhesion molecule-
Michael Loran Dustin, R. Rothlein, A. Bhan, C. Dinarello, T. Springer   +4 more
semanticscholar   +1 more source

ICAM‐1‐targeted nanocarriers attenuate endothelial release of soluble ICAM‐1, an inflammatory regulator [PDF]

Bioengineering & Translational Medicine, 2017
AbstractTargeting of drug nanocarriers (NCs) to intercellular adhesion molecule‐1 (ICAM‐1), an endothelial‐surface protein overexpressed in many pathologies, has shown promise for therapeutic delivery into and across this lining. However, due to the role of ICAM‐1 in inflammation, the effects of targeting this receptor need investigation.
Manthe, Rachel L., Muro, Silvia
openaire   +2 more sources

Circulating adhesion molecules and arterial stiffness [PDF]

, 2015
Aim: VCAM-1 and ICAM-1 are two important members of the immunoglobulin gene superfamily of adhesion molecules, and their potential role as biomarkers of diagnosis, severity and prognosis of cardiovascular disease has been investigated in a number of ...
Alihanoglu, Y.I., Evrengul, H., Findikoglu, G., Kılıç, İsmail Doğu, Rota, S., Uslu, S., Yildiz, B.S.   +6 more
core   +2 more sources

Tumor Necrosis Factor-α Contributes to Ischemia- and Reperfusion-Induced Endothelial Activation in Isolated Hearts [PDF]

, 1999
During myocardial reperfusion, polymorphonuclear neutrophil (PMN) adhesion involving the intercellular adhesion molecule-1 (ICAM-1) may lead to aggravation and prolongation of reperfusion injury.
Becker, Bernhard F., Boekstegers, Peter, Goedecke, Axel, Habazettl, Helmut, Kelly, Ralph A., Kupatt, Christian, Wolf, Dieter A., Zahler, Stefan   +7 more
core   +1 more source

Transfected HEK293 cells expressing functional recombinant intercellular adhesion molecule 1 (ICAM-1)--a receptor associated with severe Plasmodium falciparum malaria. [PDF]

PLoS ONE, 2013
Intercellular adhesion molecule 1 (ICAM-1) is a membrane-bound glycoprotein expressed on endothelial cells and cells of the immune system. Human ICAM-1 mediates adhesion and migration of leucocytes, and is implicated in inflammatory pathologies ...
Anja Bengtsson, Louise Joergensen, Zachary R Barbati, Alister Craig, Lars Hviid, Anja T R Jensen   +5 more
doaj   +1 more source

Intercellular adhesion molecule-1 expression and serum levels as markers of pre-clinical atherosclerosis in polycystic ovary syndrome

Journal of Ovarian Research, 2019
Background Polycystic ovary syndrome (PCOS) is a common reproductive endocrine disorder characterized by obesity, hyperandrogenism, and insulin resistance.
Nearmeen M. Rashad, Amal S. El-Shal, Hala G. Abomandour, Amr Mostafa Kamel Aboelfath, Mohamed el sayed Rafeek, Mohammad Samir Badr, Ayman E. Ali, Mohammed S. Yousef, Maha Abdelhamid Fathy, Mustafa taha Abdelfattah Sharaf el din   +9 more
doaj   +1 more source

ICAM-1 and S100β plasma value in children with sepsis

Jurnal Profesi Medika, 2020
ICAM-1 release during sepsis is perceived to be related to brain injury. Whereas S100β  has been known as one of brain injury markers.To measure mean value of ICAM-1, S100β, to find correlation between ICAM-1 and Glasgow Coma Scale (GCS), between S100β ...
Lisa Safira, Anton H Pudjiadi, Sukman Tulus Putra   +2 more
doaj   +1 more source

ICAM G241A polymorphism and soluble ICAM-1 serum levels: Evidence for an active immune process in schizophrenia [PDF]

, 2005
Objectives: We have previously reported reduced serum levels of soluble intercellular adhesion molecule-1 (sICAM-1) in schizophrenic patients. A single-nucleotide polymorphism ( SNP) of the ICAM-1 gene was described at position 241.
Ackenheil, Manfred, Kronig, H., Möller, Hans-Jürgen, Müller, Norbert, Riedel, M., Schwarz, Markus J., Strassnig, M.   +6 more
core   +1 more source