Results 41 to 50 of about 27,302,336 (342)
Endothelial MAPKs Direct ICAM-1 Signaling to Divergent Inflammatory Functions. [PDF]
, 2017 Lymphocyte transendothelial migration (TEM) is critically dependent on intraendothelial signaling triggered by adhesion to ICAM-1. Here we show that endothelial MAPKs ERK, p38, and JNK mediate diapedesis-related and diapedesis-unrelated functions of ICAM-
Adamson, P +10 more
core +3 more sources
Wound Healing Characteristics of ICAM-1 Null Mice Devoid of All Isoforms of ICAM-1 [PDF]
Journal of Surgical Research, 2011 Intercellular adhesion molecule-1 (ICAM-1) permits leukocyte-endothelial adhesion and transmigration during inflammation. Membrane-bound ICAM-1 knockout mice have been used to understand this molecule's role in wound-healing, but expressed spliced isoforms of ICAM-1 that may have impacted results.
Andre N, Gay +7 more
openaire +2 more sources
Endothelial preconditioning by transient oxidative stress reduces inflammatory responses of cultured endothelial cells to TNF-α [PDF]
, 2000 Brief episodes of ischemia can render an organ resistant to subsequent severe ischemia. This ‘ischemic preconditioning’ is ascribed to various mechanisms, including oxidative stress. We investigated whether preconditioning exists on an endothelial level.
Akimitsu T. +11 more
core +1 more source
Frontiers in Genetics, 2020 Delayed repair is a serious public health concern for diabetic populations. Intercellular adhesion molecule 1 (ICAM-1) and Lymphocyte function-associated antigen 1 (LFA-1) play important roles in orchestrating the repair process. However, little is known
Dongxu Qiu +7 more
doaj +1 more source
Involvement of MAPKs in ICAM-1 Expression in Glomerular Endothelial Cells in Diabetic Nephropathy [PDF]
, 2011 Inflammatory processes are involved in the pathogenesis of diabetic nephropathy. The aim of this study was to clarify the role of mitogen-activated protein kinase (MAPK) pathways for induction of intercellular adhesion molecule-1 (ICAM-1) expression in ...
Kodera, Ryo +8 more
core +1 more source
Scientific Reports, 2017 The overall objective of the study was to identify mechanisms through which intercellular adhesion molecule-1 (ICAM-1) augments the adhesive and fusogenic properties of myogenic cells.
Francis X. Pizza +6 more
doaj +1 more source
Frontiers in Immunology, 2021 The intercellular adhesion molecule-1 (ICAM-1), known as CD54, is a transmembrane cell surface glycoprotein that interacts with two integrins (i.e., LFA-1 and Mac-l) important for trans-endothelial migration of leukocytes.
Xue Zhai +8 more
doaj +1 more source
Intercellular adhesion molecule 1 promotes HIV-1 attachment but not fusion to target cells. [PDF]
PLoS ONE, 2012 Incorporation of intercellular adhesion molecule 1 (ICAM-1) into HIV-1 particles is known to markedly enhance the virus binding and infection of cells expressing lymphocyte function-associated antigen-1 (LFA-1). At the same time, ICAM-1 has been reported
Naoyuki Kondo, Gregory B Melikyan
doaj +1 more source
Role of LFA-1 and ICAM-1 in Cancer
Cancers, 2017 The lymphocyte function-associated antigen-1 (LFA-1) (also known as CD11a/CD18 and αLβ2), is just one of many integrins in the human body, but its significance is derived from its exclusive presence in leukocytes. In this review, we summarize the studies
M. Reina, E. Espel
semanticscholar +1 more source
Molecular Imaging, 2007 To examine inflammatory tissue, an initial and common symptom of various types of pathogenesis, we designed inflammation-targeted T 1 contrast agents prepared by bioconjugation of gadolinium diethylenetriaminepentaacetic acid (Gd-DTPA) with anti ...
Kyu-Sil Choi +9 more
doaj +1 more source