Single molecule and multiple bond characterization of catch bond associated cytoadhesion in malaria [PDF]
, 2017 The adhesion of malaria infected red blood cells (iRBCs) to host endothelial receptors in the microvasculature, or cytoadhesion, is associated with severe disease pathology such as multiple organ failure and cerebral malaria.
Cao, Jianshu +3 more
core +1 more source
Atherosusceptible Shear Stress Activates Endoplasmic Reticulum Stress to Promote Endothelial Inflammation. [PDF]
, 2017 Atherosclerosis impacts arteries where disturbed blood flow renders the endothelium susceptible to inflammation. Cytokine activation of endothelial cells (EC) upregulates VCAM-1 receptors that target monocyte recruitment to atherosusceptible regions ...
Bailey, Keith A +3 more
core +1 more source
Frontiers in Immunology, 2022 Breast tumors and their derived circulating cancer cells express the leukocyte β2 integrin ligand Intercellular adhesion molecule 1 (ICAM-1). We found that elevated ICAM-1 expression in breast cancer cells results in a favorable outcome and prolonged ...
Ofer Regev +14 more
doaj +1 more source
Essential role of ICAM-1 in aldosterone-induced atherosclerosis. [PDF]
, 2017 OBJECTIVE: Elevated aldosterone is associated with increased risk of atherosclerosis complications, whereas treatment with mineralocorticoid receptor (MR) antagonists decreases the rate of cardiovascular events.
Antelmi, A +10 more
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Expresión de ICAM-1 en el Endotelio de Arterias Humanas Mediante Inmunohistoquímica [PDF]
, 2011 Moore-Carrasco, R (reprint author), Univ Talca, Fac Ciencias Salud, Dept Bioquim Clin & Inmunohematol, Programa Invest Factores Riesgo Enfermedades Card, POB 747, Talca, Chile.Cardiovascular diseases (CVD) are the leading cause of death in the world ...
Donoso, W. +7 more
core +1 more source
World Electric Vehicle JournalThe worldwide commitment to the electrification of road transport will require a broad overhaul of equipment and infrastructure. Heavy-duty trucks account for over one-third of on-road energy use.
K. Darcovich +3 more
doaj +1 more source
Intracapillary leucocyte accumulation as a novel antihaemorrhagic mechanism in acute pancreatitis in mice [PDF]
, 2009 Background: Pancreatic infiltration by leucocytes represents a hallmark in acute pancreatitis. Although leucocytes play an active role in the pathophysiology of this disease, the relation between leucocyte activation, microvascular injury and haemorrhage
Deduchovas, O. +8 more
core +1 more source
Assessment of ICAM-1 N-glycoforms in mouse and human models of endothelial dysfunction.
PLoS ONE, 2020 Endothelial dysfunction is a critical event in vascular inflammation characterized, in part, by elevated surface expression of adhesion molecules such as intercellular adhesion molecule-1 (ICAM-1). ICAM-1 is heavily N-glycosylated, and like other surface
Kellie Regal-McDonald +8 more
doaj +1 more source
Exosomes derived from monocytes and from endothelial cells mediate monocyte and endothelial cell activation under high d-glucose conditions [PDF]
, 2019 Diabetes mellitus type 2 (DMT2) is characterized by hyperglycemia and associated with low grade inflammation affecting both endothelial cells and monocytes.
Faas, Marijke M. +4 more
core +2 more sources
Crucial role of local peroxynitrite formation in neutrophil-induced endothelial cell activation [PDF]
, 2003 Introduction and methods: The reaction of superoxide anions and NO not only results in a decreased availability of NO, but also leads to the formation of peroxynitrite, the role of which in the cardiovascular system is still discussed controversially. In
Gloe, Torsten +8 more
core +1 more source