Results 141 to 150 of about 385,312 (256)

Engineering Microbial Particles for Next‐Generation Biomedical Platforms

Advanced Science, EarlyView.
Microbe‐derived particles (MDPs), which include extracellular vesicles, outer membrane vesicles, inclusion bodies, polysaccharide particles, and virus‐like particles, represent a rapidly expanding category of bioinspired nanomaterials. With their natural origin, intrinsic biocompatibility, and highly programmable functionality, MDPs serve as a ...
Yuting Li, Yunjie Lu, Ziyan Huang, Jianjiang Chen, Yanbin Liu, Lei Qin, Chao Wang, Yumin Wu   +7 more
wiley   +1 more source

Maintenance of the great late Ediacaran ice age. [PDF]

Nat Commun
Liu P, Liu Y, Wang R, Li S, Sun Y, Wen B, Shen B.   +6 more
europepmc   +1 more source

Little Ice Age abruptly triggered by intrusion of Atlantic waters into the Nordic Seas. [PDF]

Sci Adv, 2021
Lapointe F, Bradley RS.
europepmc   +1 more source

Early Retinal UCHL1 Dysregulation Coupled With Synaptic Loss Reflects Alzheimer's Disease Severity

Advanced Science, EarlyView.
This study identifies synapse‐enriched deubiquitinase UCHL1 as an early Aβ‐responsive regulator of retinal synaptopathy in Alzheimer's disease. Retinal UCHL1 loss accompanies excitatory synapse degeneration, p75NTR activation, and neuroinflammation, and predicts Braak stage and cognitive decline. Aβ42 fibrils trigger synaptic and UCHL1 depletion before
Altan Rentsendorj, Jean‐Philippe Vit, Alexandre Hutton, Yosef Koronyo, Saba Shahin, Edward Robinson, Ernesto Barron, Anthony Rodriguez, Ousman Jallow, Julia Sheyn, Bhakta Prasad Gaire, Lalita Subedi, Miyah R. Davis, Barathan Gnanabharathi, Alexander V. Ljubimov, Stuart L. Graham, Vivek K. Gupta, Mehdi Mirzaei, Debra Hawes, Katlin Silm, Keith L. Black, Lon S. Schneider, Alfredo A. Sadun, Jesse G. Meyer, Dieu‐Trang Fuchs, Maya Koronyo‐Hamaoui   +25 more
wiley   +1 more source

The genomic history of Iberian horses since the last Ice Age. [PDF]

Nat Commun
Lira Garrido J, Tressières G, Chauvey L, Schiavinato S, Calvière-Tonasso L, Seguin-Orlando A, Southon J, Shapiro B, Bataille C, Birgel J, Wagner S, Khan N, Liu X, Rodanés JM, Picazo Millán JV, Giralt J, Alonso N, Aguilera I, Orsingher A, Trentacoste A, Payà X, Morán M, Iborra Eres MP, Albizuri S, Valenzuela Lamas S, Mestres Santandreu I, Duran Caixal M, Principal J, Farré Huguet J, Esteve X, Pedro Pasqual M, Sala N, Pablos A, Martín P, Vergès JM, Portero R, Arias P, Ontañón Peredo R, Detry C, Luís C, Cardoso JL, Maeir AM, Valente MJ, Grau E, Estall I Poles V, Alfonso Llorens J, Miguélez González A, Gardeisen A, Cupitò M, Tecchiati U, Bradley DG, Kolska Horwitz L, Rodríguez González E, Nieto Espinet A, Bover P, Ruiz Entrecanales R, Garcés Estallo I, Jiménez Fragoso J, Celestino S, Orlando L.   +59 more
europepmc   +1 more source

Glacial Ice Age Shapes Microbiome Composition in a Receding Southern European Glacier. [PDF]

Front Microbiol, 2021
Garcia-Lopez E, Moreno A, Bartolomé M, Leunda M, Sancho C, Cid C.   +5 more
europepmc   +1 more source

Harnessing Phase Separation for the Development of High‐Performance Hydrogels

Advanced Science, EarlyView.
ABSTRACT Hydrogels are indispensable for the development of next‐generation bioelectronics, soft robotics, and biomedical devices, where their mechanical properties determine performance and reliability. Among strategies to enhance hydrogel mechanics, phase separation enables controlled heterogeneity resulting in gel networks that are reinforced by ...
Yue Shao, Yiming Ma, Baihao Shao, Molly M. Stevens   +3 more
wiley   +1 more source

The earliest evidence of high-elevation ice age occupation in Australia. [PDF]

Nat Hum Behav
Way AM, Piper PJ, Chalker R, Wilkins D, Wilkins E, Watson Redpath L, Glass P, Carroll MR, Nutman E, Kononenko N, Spate M, Barrows TT, Wright D, Brennan W.   +13 more
europepmc   +1 more source

Phylogeography of sugar kelp: Northern ice-age refugia in the Gulf of Alaska. [PDF]

Ecol Evol, 2021
Grant WS, Chenoweth E.
europepmc   +1 more source

Multidimensional and Multifunctional Laser‐Induced Graphene (LIG) for Point‐of‐Care and Wearable Biosensing, Theranostics, and Bioactive Interfaces Toward Personalized Healthcare and Regenerative Medicine

Advanced Science, EarlyView.
Multidimensional laser‐induced graphene (LIG) spanning from 0D to 3D architectures is comprehensively reviewed for multifunctional biomedical platforms, including biosensing, theranostics, and bioactive interface applications, which highlights its potentials for point‐of‐care diagnostics, wearable health monitoring, smart drug delivery, and tissue ...
Li Zhang, Yurou Yuan, Xiaohong Ding, Wing Cheung Mak   +3 more
wiley   +1 more source