Impact of Daily Arctic Sea Ice Variability in CAM3.0 during Fall and Winter [PDF]
Climate projections suggest that an ice-free summer Arctic Ocean is possible within several decades and with this comes the prospect of increased ship traffic and safety concerns.
Bhatt, Uma S. +4 more
core
An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane
Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa +3 more
wiley +1 more source
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice +16 more
wiley +1 more source
Relationships of Biomass-Burning Aerosols to Ice in Orographic Wave Clouds [PDF]
Ice concentrations in orographic wave clouds at temperatures between −24° and −29°C were shown to be related to aerosol characteristics in nearby clear air during five research flights over the Rocky Mountains.
DeMott, Paul J. +10 more
core
Dissolved carbon and CDOM in lake ice and underlying waters along a salinity gradient in shallow lakes of Northeast China [PDF]
The variations of DOC and DIC concentrations in lake ice and underlying waters were examined in 40 shallow lakes across the Songnen Plain, Northeast China.
Du, Jia +4 more
core +1 more source
Exploiting metabolic adaptations to overcome dabrafenib treatment resistance in melanoma cells
We show that dabrafenib‐resistant melanoma cells undergo mitochondrial remodeling, leading to elevated respiration and ROS production balanced by stronger antioxidant defenses. This altered redox state promotes survival despite mitochondrial damage but renders resistant cells highly vulnerable to ROS‐inducing compounds such as PEITC, highlighting redox
Silvia Eller +17 more
wiley +1 more source
Research on Sea Ice and Local Ice Load Monitoring System for Polar Cargo Vessels
Sea ice and the resulting loads are major safety concerns for vessels operating in ice-covered regions. This study presents a tailored sea ice and local ice load monitoring system specifically designed for polar cargo vessels.
Jinhui Jiang +4 more
doaj +1 more source
Cell surface interactome analysis identifies TSPAN4 as a negative regulator of PD‐L1 in melanoma
Using cell surface proximity biotinylation, we identified tetraspanin TSPAN4 within the PD‐L1 interactome of melanoma cells. TSPAN4 negatively regulates PD‐L1 expression and lateral mobility by limiting its interaction with CMTM6 and promoting PD‐L1 degradation.
Guus A. Franken +7 more
wiley +1 more source
Beryllium-7 and Lead-210 in the atmosphere and surface snow over the Greenland ice sheet in the summer of 1989 [PDF]
The concentrations of 7Be and 210Pb were measured in surface air and fresh and aging snow samples from Summit (72°20′N, 38°45′W) and Dye 3 (65°10′N, 44°45′W) Greenland, during June and July 1989.
Dibb, Jack E.
core +2 more sources
Relationship between sea ice concentration and sea ice albedo over Antarctica
Abstract : Sea ice is a key parameter for understanding the climate change in cryosphere. In this study,we investigated the correlation with the factors that influenced change of the sea ice extent. We used the SeaIce Concentration (SIC) from Ocean and Sea Ice Satellite Application Facility (OSI-SAF), and surface albedoprovided by The Satellite ...
Minji Seo +4 more
openaire +2 more sources

