Results 41 to 50 of about 1,399 (214)

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

open access: yesFEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes   +4 more
wiley   +1 more source

A Review of Ice Core Drilling in Cave Environment – Challenges, Achievements and Future Directions

open access: yesFrontiers in Earth Science, 2022
Worldwide, more than 141 m of ice cores has been extracted from 20 cave ice deposits, with the drilling projects focusing mainly in Central European caves.
Zoltan Kern   +3 more
doaj   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

open access: yesFEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura   +2 more
wiley   +1 more source

Characterizing black carbon in rain and ice cores using coupled tangential flow filtration and transmission electron microscopy [PDF]

open access: yesAtmospheric Measurement Techniques, 2015
Antarctic ice cores have been used to study the history of black carbon (BC), but little is known with regards to the physical and chemical characteristics of these particles in the remote atmosphere.
A. Ellis   +13 more
doaj   +1 more source

Septin 9 PB domains coordinate centrosome positioning and microtubule acetylation to control epithelial polarity

open access: yesFEBS Letters, EarlyView.
Septin 9 polybasic domains couple phosphoinositide‐rich membrane binding to centrosome positioning, Golgi organization, and microtubule acetylation to control epithelial polarity. Their loss disrupts this axis, causing centrosome mispositioning, Golgi fragmentation, reduced microtubule acetylation, and polarity inversion via upregulation of the ...
Ting ting Cai   +4 more
wiley   +1 more source

Synchronization of ice core records via atmospheric gases [PDF]

open access: yesClimate of the Past, 2007
To interpret new high resolution climate records it becomes more and more important to know about the succession of climate events. Such knowledge is hard to get especially when dealing with different types of climate archives.
T. Blunier   +5 more
doaj  

Weighting alternative for water stable isotopes: Statical comparison between station- and firn/ice-records

open access: yesPolish Polar Research, 2017
It is generally accepted that ice cores archive amount-weighted water stable isotope signals. In order to achieve an improved understanding of the nature of water stable isotope signals stored in ice cores annual δ18O and δ2H averages (i.e.
Hatvani István Gábor, Kern Zoltán
doaj   +1 more source

Ubiquitination of secretory granules promotes their crinophagic degradation in Drosophila

open access: yesFEBS Letters, EarlyView.
Ubiquitination of secretory granules in Drosophila larval salivary glands is a critical molecular trigger for crinophagy, the lysosomal degradation of unreleased, or low‐quality granules. The E3 ubiquitin ligase Cnot4 is recruited to the surface of secretory granules to induce crinophagy.
Tamás Csizmadia   +6 more
wiley   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Direct linking of Greenland and Antarctic ice cores at the Toba eruption (74 ka BP) [PDF]

open access: yesClimate of the Past, 2013
The Toba eruption that occurred some 74 ka ago in Sumatra, Indonesia, is among the largest volcanic events on Earth over the last 2 million years. Tephra from this eruption has been spread over vast areas in Asia, where it constitutes a major time marker
A. Svensson   +25 more
doaj   +1 more source

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