Results 51 to 60 of about 161,313 (308)

Beyond the pseudo-time-dependent approach: chemical models of dense core precursors

open access: yes, 2010
Context: Chemical models of dense cloud cores often utilize the so-called pseudo-time-dependent approximation, in which the physical conditions are held fixed and uniform as the chemistry occurs.
Bergin   +48 more
core   +1 more source

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

open access: yesFEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li   +2 more
wiley   +1 more source

Glacio-environmental aspects recorded in two shallow ice cores drilled in 1980 at accumulation area of Khumbu Glacier of Mt. Everest in Nepal Himalayas

open access: yesArctic, Antarctic, and Alpine Research, 2020
The physical and geochemical characteristics of shallow ice cores drilled in the accumulation area (Western Cwm) of Khumbu Glacier in the Nepal Himalayas in 1980 were analyzed.
Nozomu Takeuchi   +4 more
doaj   +1 more source

Million years of Greenland Ice Sheet history recorded in ocean sediments [PDF]

open access: yes, 2011
Geological records from Tertiary and Quaternary terrestrial and oceanic sections have documented the presence of ice caps and sea ice covers both in the Southern and the Northern hemispheres since Eocene times, approximately since 45 Ma.
Jessen, Catherine   +6 more
core  

A Comparison Of New Calculations Of The Yearly 10Be Production In The Earths Polar Atmosphere By Cosmic Rays With Yearly 10Be Measurements In Multiple Greenland Ice Cores Between 1939 And 1994 - A Troubling Lack Of Concordance Paper #2

open access: yes, 2010
We have compared the yearly production rates of 10Be by cosmic rays in the Earths polar atmosphere over the last 50-70 years with 10Be measurements from two separate ice cores in Greenland.
Aldahan   +80 more
core   +3 more sources

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

Comment on “Low time resolution analysis of ice cores cannot detect impulsive nitrate events” by D. F. Smart et al. [PDF]

open access: yes, 2016
Smart et al. (2014) suggested that the detection of nitrate spikes in polar ice cores from solar energetic particle (SEP) events could be achieved if an analytical system with sufficiently high resolution was used.
Bigler, M.   +6 more
core   +2 more sources

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Optical Properties of Deep Ice at the South Pole - Absorption [PDF]

open access: yes, 1997
We discuss recent measurements of the wavelength-dependent absorption coefficients in deep South Pole ice. The method uses transit time distributions of pulses from a variable-frequency laser sent between emitters and receivers embedded in the ice.
AMANDA Collaboration   +36 more
core   +2 more sources

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

open access: yesFEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes   +4 more
wiley   +1 more source

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