Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network
FEBS Letters, EarlyView.Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley +1 more source
FEBS Letters, EarlyView.Encapsulins are protein nanocompartments that play an important role in iron storage. In the Myxococcus xanthus encapsulin system, two cargo proteins called EncB and EncC contribute to iron mineralization. Here, we show that EncB and EncC generate iron‐containing minerals with distinct chemical compositions, suggesting that the composition of stored ...
Harry B. McDowell +2 more
wiley +1 more source
A Review of Ice Core Drilling in Cave Environment – Challenges, Achievements and Future Directions
Frontiers in Earth Science, 2022 Worldwide, more than 141 m of ice cores has been extracted from 20 cave ice deposits, with the drilling projects focusing mainly in Central European caves.
Zoltan Kern +3 more
doaj +1 more source
An assessment of key model parametric uncertainties in projections of Greenland Ice Sheet behavior [PDF]
, 2012 Lack of knowledge about the values of ice sheet model input parameters introduces substantial uncertainty into projections of Greenland Ice Sheet contributions to future sea level rise.
Stone, Emma J. +17 more
core +2 more sources
Chronology for climate change: Developing age models for the biogeochemical ocean flux study cores [PDF]
, 1995 We construct age models for a suite of cores from the northeast Atlantic Ocean by means of accelerator mass spectrometer dating of a key core, BOFS 5K, and correlation with the rest of the suite.
Manighetti, B +3 more
core
Stratigraphy of sea-ice cores collected in the Eurasian basin during CAATEX 2019 cruise
, 2023 The physical properties of sea ice, including salinity, sea ice temperature, and sea ice texture as well as isotopic composition (oxygen and hydrogen) were analyzed from samples collected on the CAATEX 2019 expedition to the central Arctic Ocean (between
Granskog, Mats A +6 more
core +1 more source
Late Quaternary ice-ocean interactions in central West Greenland [PDF]
, 2011 A greater knowledge of the interactions between the Greenland Ice Sheet and climate is critical to understanding the possible impacts of future global warming, including ice sheet contribution to global sea-level rise and perturbations to ocean ...
MCCARTHY, DAVID,JOHN +1 more
core
Greenland Summit Ice Cores CD-ROM as zip-archive
, 2017 Greenland Summit Ice Cores CD-ROM as zip ...
GRIP/GISP +3 more
core +1 more source
Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization
Molecular Oncology, EarlyView.In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu +13 more
wiley +1 more source
Novel approach to estimate the water isotope diffusion length in deep ice cores with an application to Marine Isotope Stage 19 in the Dome C ice core [PDF]
The CryosphereAccurate estimates of water isotope diffusion lengths are crucial when reconstructing and interpreting water isotope records from ice cores. This is especially true in the deepest, oldest sections of deep ice cores, where thermally enhanced diffusive ...
F. Shaw +5 more
doaj +1 more source