Results 61 to 70 of about 161,313 (308)
FEBS Letters, EarlyView.Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source
Synchronization of ice core records via atmospheric gases [PDF]
Climate of the Past, 2007 To interpret new high resolution climate records it becomes more and more important to know about the succession of climate events. Such knowledge is hard to get especially when dealing with different types of climate archives.
T. Blunier +5 more
doaj
Polish Polar Research, 2017 It is generally accepted that ice cores archive amount-weighted water stable isotope signals. In order to achieve an improved understanding of the nature of water stable isotope signals stored in ice cores annual δ18O and δ2H averages (i.e.
Hatvani István Gábor, Kern Zoltán
doaj +1 more source
Two ice-core delta O-18 records from Svalbard illustrating climate and sea-ice variability over the last 400 years [PDF]
, 2005 Ice cores from the relatively low-lying ice caps in Svalbard have not been widely exploited in climatic studies owing to uncertainties about the effect of meltwater percolation.
Igarashi, M +15 more
core +2 more sources
Molecular Oncology, EarlyView.Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice +16 more
wiley +1 more source
Characterizing black carbon in rain and ice cores using coupled tangential flow filtration and transmission electron microscopy [PDF]
Atmospheric Measurement Techniques, 2015 Antarctic ice cores have been used to study the history of black carbon (BC), but little is known with regards to the physical and chemical characteristics of these particles in the remote atmosphere.
A. Ellis +13 more
doaj +1 more source
Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin
Molecular Oncology, EarlyView.The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla +10 more
wiley +1 more source
Glycolaldehyde formation via the dimerization of the formyl radical [PDF]
, 2013 Glycolaldehyde, the simplest monosaccharide sugar, has recently been detected in low- and high-mass star-forming cores. Following our previous investigation into glycolaldehyde formation, we now consider a further mechanism for the formation of ...
Baulch +30 more
core +2 more sources
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
Direct linking of Greenland and Antarctic ice cores at the Toba eruption (74 ka BP) [PDF]
Climate of the Past, 2013 The Toba eruption that occurred some 74 ka ago in Sumatra, Indonesia, is among the largest volcanic events on Earth over the last 2 million years. Tephra from this eruption has been spread over vast areas in Asia, where it constitutes a major time marker
A. Svensson +25 more
doaj +1 more source