Results 81 to 90 of about 702,524 (252)

Little ice age clearly recorded in northern Greenland ice cores [PDF]

open access: yes, 1998
Four ice cores drilled in the little investigated area of northern and northeastern Greenland were evaluated for their isotopic (δ18O) and chemical content.
Schwager, M.   +10 more
core   +2 more sources

Thermal Sidewall Ice Corer (TSIC) to recover samples from boreholes drilled in glaciers and ice sheets

open access: yesJournal of Glaciology
The proposed Thermal Sidewall Ice Corer (TSIC) is designed to accurately sample horizontal ice layers of scientific interest, such as tephra layers, basal ice and shear zones, and retrieve ice cores back to the surface. The system features a bending core
Xianzhe Wei   +5 more
doaj   +1 more source

Protocol for quantifying miRNA trafficking across the endosomal membrane

open access: yesFEBS Open Bio, EarlyView.
An in vitro protocol measures miRNA uptake into endosomes isolated from mammalian cell extracts, which are free of subcellular contaminants. Performed at 37 °C in the presence of ATP, it ensures the import of single‐stranded miRNA into the endosomal lumen.
Syamantak Ghosh   +2 more
wiley   +1 more source

Structural and biochemical insights into the thermostable esterase Ta0887 from Thermoplasma acidophilum

open access: yesFEBS Open Bio, EarlyView.
In this study, a novel esterase from the thermoacidophilic archaeon Thermoplasma acidophilum was biochemically and structurally characterized. Our results demonstrate that Ta0887 is a highly thermostable esterase that preferentially hydrolyzes p‐nitrophenyl hexanoate and possesses an α‐helical cap domain that likely contributes to its substrate ...
Alejandro Delgado‐Rey   +4 more
wiley   +1 more source

The C‐terminal domain of yeast Arginyltransferase1 is essential for its catalytic activity

open access: yesFEBS Open Bio, EarlyView.
Arginyltransferase 1 (Ate1), a eukaryotic enzyme, catalyses arginylation, transferring arginine from tRNA‐Arg to the amino terminus of the target protein. Overexpression of Ate1 in yeast is lethal and is dependent on arginylation. This study elucidates how mutations in the cofactor‐binding and active site of Ate1 and truncation of its structural ...
Vikas Kumar Yadav   +4 more
wiley   +1 more source

Seasonal Variations in Hydrogen Peroxide in Polar Ice Cores [PDF]

open access: yes, 1988
Hydrogen peroxide is present in polar snow and ice in remarkably high concentrations. With values up to 300 ppb, H2O2 is one of the most concentrated impurities in polar ice.
Sigg, Andreas   +3 more
core   +1 more source

Temperature profile of different summer sea-ice cores collected in the Eurasian basin during CAATEX 2019 cruise

open access: yes, 2023
The physical properties of sea ice, including salinity, sea ice temperature, and sea ice texture as well as isotopic composition (oxygen and hydrogen) were analyzed from samples collected on the CAATEX 2019 expedition to the central Arctic Ocean (between
Granskog, Mats A   +6 more
core   +1 more source

Cover ICE 2019

open access: yes, 2019
These proceedings are a collection of papers presented in English at The Second PGSD UST International Conference on Education (ICE) held in Universitas Sarjanawiyata Tamansiswa on October 5, 2019.
ICE 2019, ICE 2019
core   +1 more source

Coring of Antarctic Subglacial Sediments

open access: yesJournal of Marine Science and Engineering, 2019
Coring sediments in subglacial aquatic environments offers unique opportunities for research on paleo-environments and paleo-climates because it can provide data from periods even earlier than ice cores, as well as the overlying ice histories ...
Da Gong   +19 more
doaj   +1 more source

TRPML1 agonist ML‐SA5 attenuates pulmonary fibroblast activation by suppressing mTOR and restoring autophagic flux

open access: yesFEBS Open Bio, EarlyView.
TGF‐β1 stimulation downregulates lysosomal channel TRPML1 in pulmonary fibroblasts. The TRPML1 agonist ML‐SA5 suppressed fibroblast‐to‐myofibroblast activation and collagen production. Mechanistically, ML‐SA5 inhibited mTOR phosphorylation, restored autophagic flux, and its effects were enhanced by rapamycin (mTOR inhibitor) and reversed by MHY1485 ...
Jiatong Yao   +10 more
wiley   +1 more source

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