Results 81 to 90 of about 161,313 (308)

Microglial dynamics and ferroptosis induction in human iPSC‐derived neuron–astrocyte–microglia tri‐cultures

FEBS Open Bio, EarlyView.
A tri‐culture of iPSC‐derived neurons, astrocytes, and microglia treated with ferroptosis inducers as an Induced ferroptosis model was characterized by scRNA‐seq, cell survival, and cytokine release assays. This analysis revealed diverse microglial transcriptomic changes, indicating that the system captures key aspects of the complex cellular ...
Hongmei Lisa Li, Hiroko Ohmiya, Sou Sakamoto, Masato Yugami, Akiko Oki, Makoto Furusawa, Yan Ling   +6 more
wiley   +1 more source

Reconstruction of solar activity for the last millennium using $^{10}$Be data

, 2003
In a recent paper (Usoskin et al., 2002a), we have reconstructed the concentration of the cosmogenic $^{10}$Be isotope in ice cores from the measured sunspot numbers by using physical models for $^{10}$Be production in the Earth's atmosphere, cosmic ray ...
Alanko, K., Mursula, K., Schuessler, M., Solanki, S., Usoskin, I. G.   +4 more
core   +1 more source

Ice core records of atmospheric CO2 around the last three glacial terminations [PDF]

, 1999
Air trapped in bubbles in polar ice cores constitutes an archive for the reconstruction of the global carbon cycle and the relation between greenhouse gases and climate in the past.
Deck, B., Fischer, Hubertus, Mastroianni, D., Smith, J., Wahlen, M.   +4 more
core   +1 more source

Differential regulation of ZFAS1 splice variants by endoplasmic reticulum stress in hepatocyte cell lines

FEBS Open Bio, EarlyView.
ZFAS1 is a lncRNA promoting cell proliferation and migration, exhibiting high expression in various cancers. It is conserved, widely expressed, and produces multiple splice variants with unclear roles. We identified several splice variants in hepatocyte models, and found that inhibiting or suppressing regulators of the unfolded protein response (PERK ...
Sébastien Soubeyrand, Paulina Lau, Ruth McPherson   +2 more
wiley   +1 more source

Thermal Sidewall Ice Corer (TSIC) to recover samples from boreholes drilled in glaciers and ice sheets

Journal of Glaciology
The proposed Thermal Sidewall Ice Corer (TSIC) is designed to accurately sample horizontal ice layers of scientific interest, such as tephra layers, basal ice and shear zones, and retrieve ice cores back to the surface. The system features a bending core
Xianzhe Wei, Pavel G. Talalay, Da Gong, Yazhou Li, Xiaopeng Fan, Gaoli Zhao   +5 more
doaj   +1 more source

Global perspective of nitrate flux in ice cores [PDF]

, 1995
The relationships between the concentration and the flux of chemical species (Cl-, NO3 - , SO42-, Na +, K + , NH4 + , Mg 2+ , Ca 2+) versus snow accumulation rate were examined at GISP2 and 20D in Greenland, Mount Logan from the St.
Dibb, Jack E., Linder, Ernst, Mayewski, Paul A, Morrison, Michael, Talbot, R., Twickler, Mark S, Whitlow, Sallie I, Yang, Qinzhao   +7 more
core   +3 more sources

Screening and epitope characterization of Nidogen‐2‐specific nanobodies

FEBS Open Bio, EarlyView.
Camel immunization and phage display were employed to generate high‐affinity VHH nanobodies against Nidogen‐2. After library construction, biopanning, ELISA screening, sequencing, and recombinant expression, selected nanobodies were purified and characterized, leading to the preliminary exploration of a nanobody‐based sandwich ELISA for specific ...
Jianchuan Wen, Qianqian Cui, Zhongyun Lan, Yingjun Wang, Shuaiying Zhao, Wenxuan Feng, Yunfeng Liu, Qiting Huang, Dongna Zhang, Jianfeng Xu   +9 more
wiley   +1 more source

Coring of Antarctic Subglacial Sediments

Journal of Marine Science and Engineering, 2019
Coring sediments in subglacial aquatic environments offers unique opportunities for research on paleo-environments and paleo-climates because it can provide data from periods even earlier than ice cores, as well as the overlying ice histories ...
Da Gong, Xiaopeng Fan, Yazhou Li, Bing Li, Nan Zhang, Raphael Gromig, Emma C. Smith, Wolf Dummann, Sophie Berger, Olaf Eisen, Jan Tell, Boris K. Biskaborn, Nikola Koglin, Frank Wilhelms, Benjamin Broy, Yunchen Liu, Yang Yang, Xingchen Li, An Liu, Pavel Talalay   +19 more
doaj   +1 more source

Cosmic-ray induced diffusion in interstellar ices

, 2014
Cosmic rays are able to heat interstellar dust grains. This may enhance molecule mobility in icy mantles that have accumulated on the grains in dark cloud cores.
Kalvans, Juris
core   +2 more sources

YlmG1 is localized exclusively to the chloroplast envelope membrane and is involved in preprotein translocation in Arabidopsis thaliana

FEBS Open Bio, EarlyView.
Cytosolically synthesized chloroplast preproteins are translocated across the outer and inner envelope membranes through translocons called TOC and TIC, respectively. In green algae and plants, the TIC core is composed of essential membrane proteins, Tic12, Tic20, and Tic214.
Mengyi Li, Xueyang Zhao, Masato Nakai
wiley   +1 more source