Results 111 to 120 of about 226,235 (355)

CRISPR in MOF Formulation with Enhanced Stability, Activity, and Altered PAM Specificity for Broad‐Spectrum Diagnosis of Bacterial Sepsis

open access: yesAdvanced Science, EarlyView.
CRISPR‐FLEXMO (CRISPR with flexible PAM in MOF encapsulation) integrates a PAM‐relaxed Cas12a K607R enzyme with a manganese‐coordinated MOF for broad‐spectrum diagnosis of bacterial sepsis. The MOF enhances activity and preserves functionality under heat, solvent, and chaotropic stress, supporting long‐term room‐temperature storage.
Tathagata Pal   +3 more
wiley   +1 more source

OPTRACE: Optical Imaging–Guided Transplantation and Tracking of Cells in the Mouse Brain

open access: yesAdvanced Science, EarlyView.
OPTRACE establishes an optical, two‐step platform for intracerebral cell therapy. Transparent glass pipettes enable real‐time, image‐guided delivery, while multiplex genetic labeling with two‐photon and bioluminescence readouts supports longitudinal single‐cell tracking and host–graft dynamics.
Jinghui Wang   +10 more
wiley   +1 more source

High basal melting forming a channel at the grounding line of Ross Ice Shelf, Antarctica [PDF]

open access: yes, 2016
Antarctica's ice shelves are thinning at an increasing rate, affecting their buttressing ability. Channels in the ice shelf base unevenly distribute melting, and their evolution provides insight into changing subglacial and oceanic conditions.
Catania, Ginny   +6 more
core   +1 more source

Stimuli‐Responsive Supramolecular Biomaterials for Cancer Theranostics

open access: yesAdvanced Science, EarlyView.
The ultimate goal of cancer theranostics is to get imaging agents and therapeutic cargo to tumor sites when and where they are required. “Smart” systems should be developed. This review discusses the characteristics of physiological stimuli, types and action modes of external stimuli, construction approaches and working principles, as well as ...
Wenting Hu   +4 more
wiley   +1 more source

Ice-Shelf Underwater Morphology [PDF]

open access: yesJournal of Glaciology, 1979
AbstractA side-scan sonar survey was conducted near the ice front of Riiser-Larsenisen during the 1976–77 Norwegian Antarctic Research Expedition to investigate the underwater ice-shelf morphology. The survey covered several shorter, widely-spaced sections, for a total of about 10 km along the ice front.
openaire   +1 more source

Deep Learning‐Powered Scalable Cancer Organ Chip for Cancer Precision Medicine

open access: yesAdvanced Science, EarlyView.
This scalable, low‐cost Organ Chip platform, made via injection molding, uses capillary pinning for hydrogel confinement and supports versatile tissue coculture and robust imaging. Deep learning enables label‐free, sensitive phenotypic analysis.
Yu‐Chieh Yuan   +24 more
wiley   +1 more source

Assets for "Simulation-Based Inference of Surface Accumulation and Basal Melt Rates of an Antarctic Ice shelf from Isochronal Layers"

open access: green, 2023
Guy Moss   +6 more
openalex   +1 more source

Stress‐Induced Melting Controlled Failure Mechanisms of Methane Hydrate

open access: yesAdvanced Science, EarlyView.
We study methane hydrate via nanoindentation and nuclear magnetic resonance (NMR), finding its regional melting and mechanical properties, challenging existing views on hydrogen‐bonded crystals. Abstract Methane hydrate, a kind of nonstoichiometric crystalline, attracted worldwide attentions as a promising substitute energy. Its Dissociation is thought
Yanlong Li   +9 more
wiley   +1 more source

Finite Element Analysis of Small Scale Continuous Calving [PDF]

open access: yes, 2013
Ice shelves are floating ice masses, which are sensitive to climate changes. The main mechanisms for the mass loss of ice shelves around Antarctica are basal melting and calving.
Christmann, Julia   +3 more
core  

Observed vulnerability of Filchner-Ronne Ice Shelf to wind-driven inflow of warm deep water [PDF]

open access: yes, 2016
The average rate of melting at the base of the large Filchner-Ronne Ice Shelf in the southern Weddell Sea is currently low, but projected to increase dramatically within the next century.
Darelius, E., Fer, I., Nicholls, K.W.
core   +2 more sources

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