Results 101 to 110 of about 478,422 (316)

Preparation and characterization of renal cell peptides from fetal rats for their antitumor activity

FEBS Open Bio, EarlyView.
This study aimed to prepare renal cells (RCs) from fetal rats which were digested by enzymes. Candidate peptides RCPs were characterized by capillary HPLC and MS and their bioactivity was predicted using peptideranker. The predicted top 10 bioactive peptides were synthesized.
Zhe Zhang, Yuan Cao, Jing Du, Ying Zhang, Junxia Wang, Ying Yuan, Lianqing Sun   +6 more
wiley   +1 more source

Late Pleistocene glacial terminations accelerated by proglacial lakes [PDF]

Climate of the Past
During the glacial cycles of the past 800 000 years, Eurasia and North America were periodically covered by large ice sheets, causing up to 100 m of sea-level change.
M. D. W. Scherrenberg, C. J. Berends, R. S. W. van de Wal, R. S. W. van de Wal   +3 more
doaj   +1 more source

On the Disintegration of Ice Shelves: the Role of Thinning [PDF]

Annals of Glaciology, 1982
It is proposed that an ice shelf disintegrates when its calving front retreats faster than its grounding line. This paper examines the role of ice thinning in grounding-line retreat. Thinning occurs as a result of creep spreading and ice melting. Thinning by creep is examined for the general regime of bending converging flow in an ice shelf lying in a ...
openaire   +2 more sources

CD9‐association with PIP2 areas is regulated by a CD9 salt bridge

FEBS Open Bio, EarlyView.
The tetraspanin CD9 has an intracellular salt bridge. If CD9 opens, open‐CD9 moves from PIP2‐rich areas to regions populated by its interaction partner EWI‐2. Hence, the state of the salt bridge regulates the distribution of CD9 and by this CD9‐EWI‐2 complex formation.
Yahya Homsi, Sara C. Konopka, Thorsten Lang   +2 more
wiley   +1 more source

Antarctic ice-shelf meltwater outflows in satellite radar imagery: ground-truthing and basal channel observations

Journal of Glaciology
Ice shelves regulate the flow of the Antarctic ice sheet toward the ocean and its contribution to sea-level rise. Accurately monitoring the basal and surface melting of ice shelves is therefore essential for predicting the ice sheet's response to ...
Jakob Stanley Hamann, Thomas Arney, James David Kirkham, Paul Wachter, Karsten Gohl   +4 more
doaj   +1 more source

Characterization of WAC interactions with R2TP and TTT chaperone complexes linking glucose and glutamine availability to mTORC1 activity

FEBS Open Bio, EarlyView.
TTT and R2TP chaperone complexes are required for the assembly and activation of mTORC1. WAC directly interacts with components of TTT, R2TP, and mTORC1, and these interactions are affected by the availability of glucose and glutamine, correlating with changes in mTORC1 activity.
Sofía Cabezudo, Natalia Cuervo, Carmen García‐Martín, Andrés López‐Perrote, Clara Reglero, Adrián Maqueda‐Real, Ana González‐Corpas, Marina Serna, Diego Megías, Alejo Efeyan, Solip Park, Oscar Llorca   +11 more
wiley   +1 more source

Brief communication: PICOP, a new ocean melt parameterization under ice shelves combining PICO and a plume model

The Cryosphere, 2018
. Basal melting at the bottom of Antarctic ice shelves is a major control on glacier dynamics, as it modulates the amount of buttressing that floating ice shelves exert onto the ice streams feeding them.
T. Pelle, Mathieu Morlighem, J. Bondzio
semanticscholar   +1 more source

Polydatin ameliorates ovalbumin‐induced asthma in a rat model through NCOA4‐mediated ferroautophagy and ferroptosis pathway

FEBS Open Bio, EarlyView.
In this research, a rat model of asthma was created using OVA, and polydatin served as an intervention. By inhibiting ferroautophagy mediated by NCOA4 and averting ferroptosis, polydatin has been demonstrated to reduce asthma. This work presents new ideas for investigating the mechanism of polydatin's ability to alleviate asthma, in addition to ...
Wei Li, Yuwei Tang, Wenkang Liu, Fang Fang, Jiepeng Wang, Chaoyi Fang   +5 more
wiley   +1 more source

Firn air content changes on Antarctic ice shelves under three future warming scenarios [PDF]

The Cryosphere
The Antarctic firn layer provides pore space in which an estimated 94 % to 96 % of the surface melt refreezes or is retained as liquid water. Future depletion of firn pore space by increased surface melt, densification and formation of low-permeability ...
S. B. M. Veldhuijsen, S. B. M. Veldhuijsen, W. J. van de Berg, P. Kuipers Munneke, M. R. van den Broeke   +4 more
doaj   +1 more source

Downregulation of sST2, a decoy receptor for interleukin‐33, enhances subcutaneous tumor growth in murine pancreatic cancer cells

FEBS Open Bio, EarlyView.
Subcutaneous implantation of murine Panc02 pancreatic cancer cells depleted of sST2, a soluble decoy receptor for the proinflammatory interleukin‐33 (IL‐33), leads to a decreased number of GLUT4‐positive cancer‐associated adipocytes, reduced levels of the anti‐inflammatory molecule adiponectin, increased phosphorylation of IκBα, elevated Cxcl3 ...
Miho Akimoto, Nobuko Koshikawa, Takao Morinaga, Mimi Tamamori‐Adachi, Atsushi Takatori, Keizo Takenaga   +5 more
wiley   +1 more source