Results 21 to 30 of about 417,097 (363)

Dose reduction to organs at risk with deep-inspiration breath-hold during right breast radiotherapy: a treatment planning study

Radiation Oncology, 2019
Background The addition of regional nodal radiation (RNI) to whole breast irradiation for high risk breast cancer improves metastases free survival and new data suggests it contributes additional benefit to overall survival. Deep inspiration breath hold (
Chloe Pandeli, Lloyd M. L. Smyth, Steven David, Andrew W. See   +3 more
doaj   +1 more source

To what degree are orphan drugs patient-centered? A review of the current state of clinical research in rare diseases

Orphanet Journal of Rare Diseases, 2020
Background Over the past 30 years, the healthcare industry has increasingly turned its attention to rare diseases. Regulators have emphasized the need for clinical research in this area to be patient-centered.
Sally Lanar, Catherine Acquadro, James Seaton, Isabelle Savre, Benoit Arnould   +4 more
doaj   +1 more source

Content validation and psychometric evaluation of the Angioedema Quality of Life Questionnaire for hereditary angioedema

Journal of Patient-Reported Outcomes, 2023
Background There is considerable burden of illness in hereditary angioedema (HAE). However, instruments to assess health-related quality of life (HRQoL) in HAE are limited.
Magdalena Vanya, Maureen Watt, Saeid Shahraz, Charlotte E. Kosmas, Stephanie Rhoten, Sara Costa-Cabral, Joan Mendivil, Giovanna Devercelli, Karsten Weller   +8 more
doaj   +1 more source

ICON in Climate Limited-area Mode (ICON release version 2.6.1): a new regional climate model [PDF]

Geoscientific Model Development, 2021
For the first time, the Limited-Area Mode of the new ICON (Icosahedral Nonhydrostatic) weather and climate model has been used for a continuous long-term regional climate simulation over Europe.
T. V. Pham, C. Steger, B. Rockel, K. Keuler, I. Kirchner, M. Mertens, D. Rieger, G. Zängl, B. Früh   +8 more
doaj   +1 more source

Correction to: Cost-effectiveness analysis of umeclidinium bromide/vilanterol 62.5/25 mcg versus tiotropium/olodaterol 5/5 mcg in symptomatic patients with chronic obstructive pulmonary disease: a Spanish National Healthcare System perspective

Respiratory Research, 2019
Following publication of the original article [1], we have been notified of the below corrections to the 5th paragraph in the Discussion section.
M. T. Driessen, J. Whalen, B. Seewoodharry Buguth, L. A. Vallejo-Aparicio, I. P. Naya, Y. Asukai, B. Alcázar-Navarrete, M. Miravitlles, F. García-Río, N. A. Risebrough   +9 more
doaj   +1 more source

Iconic semiosis and representational efficiency in the London Underground Diagram [PDF]

, 2014
The icon is the type of sign connected to efficient representational features, and its manipulation reveals more information about its object. The London Underground Diagram (LUD) is an iconic artifact and a well-known example of representational ...
Atã, Pedro, Bitarello, Breno, Queiroz, Joao   +2 more
core   +1 more source

A systematic literature review and network meta-analysis feasibility study to assess the comparative efficacy and comparative effectiveness of pneumococcal conjugate vaccines

Human Vaccines & Immunotherapeutics, 2019
Background: No head-to-head studies are currently available comparing pneumococcal non-typeable Haemophilus influenzae protein D conjugate vaccine (PHiD-CV) with 13-valent pneumococcal conjugate vaccine (PCV-13).
Ashleigh McGirr, Shehzad M. Iqbal, Patricia Izurieta, Carla Talarico, Janneke Luijken, Josefine Redig, Rachel S. Newson   +6 more
doaj   +1 more source

Real-World Patient Experience on the Path to Diagnosis of Ankylosing Spondylitis

Rheumatology and Therapy, 2019
Introduction We describe the journey to diagnosis of ankylosing spondylitis (AS) from the patient perspective and examine differences in this journey by sex.
Alexis Ogdie, W. Benjamin Nowell, Regan Reynolds, Kelly Gavigan, Shilpa Venkatachalam, Marie de la Cruz, Emuella Flood, Ethan J. Schwartz, Beverly Romero, Yujin Park   +9 more
doaj   +1 more source

Cost-effectiveness analysis of umeclidinium bromide/vilanterol 62.5/25 mcg versus tiotropium/olodaterol 5/5 mcg in symptomatic patients with chronic obstructive pulmonary disease: a Spanish National Healthcare System perspective

Respiratory Research, 2018
Background A head-to-head study demonstrated the superiority of once-daily umeclidinium bromide/vilanterol (UMEC/VI) 62.5/25 mcg on trough forced expiratory volume in 1 s (FEV1) versus once-daily tiotropium/olodaterol (TIO/OLO) 5/5 mcg in symptomatic ...
M. T. Driessen, J. Whalen, B. Seewoodharry Buguth, L. A. Vallejo-Aparicio, I. P. Naya, Y. Asukai, B. Alcázar-Navarrete, M. Miravitlles, F. García-Río, N. A. Risebrough   +9 more
doaj   +1 more source

Patient perspectives on the pathway to psoriatic arthritis diagnosis: results from a web-based survey of patients in the United States

BMC Rheumatology, 2020
Background There are limited real-world data on the diagnostic experiences of patients with psoriatic arthritis (PsA), including medical care sought and potential barriers to diagnosis.
Alexis Ogdie, W. Benjamin Nowell, Eddie Applegate, Kelly Gavigan, Shilpa Venkatachalam, Marie de la Cruz, Emuella Flood, Ethan J. Schwartz, Beverly Romero, Peter Hur   +9 more
doaj   +1 more source