Results 11 to 20 of about 41,538 (268)

Indirect Comparison of Lanadelumab and Intravenous C1-INH Using Data from the HELP and CHANGE Studies: Bayesian and Frequentist Analyses

Drugs in R&D, 2021
Background Hereditary angioedema (HAE) with C1-esterase inhibitor (C1-INH) deficiency is a rare disease associated with painful, potentially fatal swelling episodes affecting subcutaneous or submucosal tissues.
Joan Mendivil, Mia Malmenäs, Katrin Haeussler, Matthias Hunger, Gagan Jain, Giovanna Devercelli   +5 more
doaj   +1 more source

Power Spiral Enteroscopy: A Quick and Powerful Dive Deep Inside the Small Bowel!

Journal of Digestive Endoscopy, 2022
A comprehensive and detailed small bowel evaluation became possible since 2001 with the advent of a wireless capsule endoscope that was primarily used for diagnostic purposes.
Chalapathi Rao Achanta, Vasanthika Imandi, Sudhanva V. Kinhal, Sridhar Sundharam, Manas Panigrahi, Sneha Shanthi Didchela, Swetha Hanumanthu, Raja Mahesh Kunchala, Amninder Singh   +8 more
doaj   +1 more source

To what degree are orphan drugs patient-centered? A review of the current state of clinical research in rare diseases

Orphanet Journal of Rare Diseases, 2020
Background Over the past 30 years, the healthcare industry has increasingly turned its attention to rare diseases. Regulators have emphasized the need for clinical research in this area to be patient-centered.
Sally Lanar, Catherine Acquadro, James Seaton, Isabelle Savre, Benoit Arnould   +4 more
doaj   +1 more source

Dose reduction to organs at risk with deep-inspiration breath-hold during right breast radiotherapy: a treatment planning study

Radiation Oncology, 2019
Background The addition of regional nodal radiation (RNI) to whole breast irradiation for high risk breast cancer improves metastases free survival and new data suggests it contributes additional benefit to overall survival. Deep inspiration breath hold (
Chloe Pandeli, Lloyd M. L. Smyth, Steven David, Andrew W. See   +3 more
doaj   +1 more source

Cost-effectiveness analysis of umeclidinium bromide/vilanterol 62.5/25 mcg versus tiotropium/olodaterol 5/5 mcg in symptomatic patients with chronic obstructive pulmonary disease: a Spanish National Healthcare System perspective

Respiratory Research, 2018
Background A head-to-head study demonstrated the superiority of once-daily umeclidinium bromide/vilanterol (UMEC/VI) 62.5/25 mcg on trough forced expiratory volume in 1 s (FEV1) versus once-daily tiotropium/olodaterol (TIO/OLO) 5/5 mcg in symptomatic ...
M. T. Driessen, J. Whalen, B. Seewoodharry Buguth, L. A. Vallejo-Aparicio, I. P. Naya, Y. Asukai, B. Alcázar-Navarrete, M. Miravitlles, F. García-Río, N. A. Risebrough   +9 more
doaj   +1 more source

Content validation and psychometric evaluation of the Angioedema Quality of Life Questionnaire for hereditary angioedema

Journal of Patient-Reported Outcomes, 2023
Background There is considerable burden of illness in hereditary angioedema (HAE). However, instruments to assess health-related quality of life (HRQoL) in HAE are limited.
Magdalena Vanya, Maureen Watt, Saeid Shahraz, Charlotte E. Kosmas, Stephanie Rhoten, Sara Costa-Cabral, Joan Mendivil, Giovanna Devercelli, Karsten Weller   +8 more
doaj   +1 more source

Correction to: Cost-effectiveness analysis of umeclidinium bromide/vilanterol 62.5/25 mcg versus tiotropium/olodaterol 5/5 mcg in symptomatic patients with chronic obstructive pulmonary disease: a Spanish National Healthcare System perspective

Respiratory Research, 2019
Following publication of the original article [1], we have been notified of the below corrections to the 5th paragraph in the Discussion section.
M. T. Driessen, J. Whalen, B. Seewoodharry Buguth, L. A. Vallejo-Aparicio, I. P. Naya, Y. Asukai, B. Alcázar-Navarrete, M. Miravitlles, F. García-Río, N. A. Risebrough   +9 more
doaj   +1 more source

Patient perspectives on the pathway to psoriatic arthritis diagnosis: results from a web-based survey of patients in the United States

BMC Rheumatology, 2020
Background There are limited real-world data on the diagnostic experiences of patients with psoriatic arthritis (PsA), including medical care sought and potential barriers to diagnosis.
Alexis Ogdie, W. Benjamin Nowell, Eddie Applegate, Kelly Gavigan, Shilpa Venkatachalam, Marie de la Cruz, Emuella Flood, Ethan J. Schwartz, Beverly Romero, Peter Hur   +9 more
doaj   +1 more source

A systematic literature review and network meta-analysis feasibility study to assess the comparative efficacy and comparative effectiveness of pneumococcal conjugate vaccines

Human Vaccines & Immunotherapeutics, 2019
Background: No head-to-head studies are currently available comparing pneumococcal non-typeable Haemophilus influenzae protein D conjugate vaccine (PHiD-CV) with 13-valent pneumococcal conjugate vaccine (PCV-13).
Ashleigh McGirr, Shehzad M. Iqbal, Patricia Izurieta, Carla Talarico, Janneke Luijken, Josefine Redig, Rachel S. Newson   +6 more
doaj   +1 more source

Development and Validation of a Canine Health-Related Quality of Life Questionnaire and a Human–Canine Bond Questionnaire for Use in Veterinary Practice

Animals, 2023
The use of valid questionnaires to assess dogs’ health-related quality of life (HRQoL) in veterinary practice can improve canine health outcomes and communications between veterinarians and caretakers of dogs. The Canine HRQoL Questionnaire (Canine HRQoL-
Robert P. Lavan, Muna Tahir, Christina O’Donnell, Alex Bellenger, Elodie de Bock, Patricia Koochaki   +5 more
doaj   +1 more source