Results 41 to 50 of about 127,559 (313)

The ICON Challenge on Algorithm Selection [PDF]

open access: yes, 2017
Algorithm selection is of increasing practical relevance in a variety of applications. Many approaches have been proposed in the literature, but their evaluations are often not comparable, making it hard to judge which approaches work best.
Barry O'Sullivan   +5 more
core   +1 more source

COVID-19 Vaccination Recommendations for Immunocompromised Patient Populations: Delphi Panel and Consensus Statement Generation in the United States

open access: yesInfectious Diseases and Therapy
Introduction The United States Advisory Committee on Immunization Practices (ACIP) and the Centers for Disease Control (CDC) recommend COVID-19 vaccines for all immunocompromised individuals.
Kira Zhi Hua Lai   +5 more
doaj   +1 more source

Icon, Symbol and Values of Functional and Aesthetic Communication in Industrial Product Design

open access: yesالاكاديمي, 2021
The icon and the symbol represent the constituents of the communication process, through their intellectual and philosophical concepts that have been addressed by the current research that it has touched upon their importance in conveying the design idea
Ziad Hatem Harbi
doaj   +1 more source

Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations

open access: yesFEBS Letters, EarlyView.
The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas   +6 more
wiley   +1 more source

Issues and development trends of modern Icon painting [PDF]

open access: yesSHS Web of Conferences, 2019
The article is concerned with topical issues and problem points of modern icon painting: understanding meanings and the mission of the icon in society, position of the Church, issue of the canon in icon painting, commercialization of the icon painter’s ...
Bobreshova Marina
doaj   +1 more source

An unexpected alternative viologen electron mediator site in tungsten‐containing formate dehydrogenase

open access: yesFEBS Letters, EarlyView.
An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley   +1 more source

Icon of Saint Nicholas

open access: yes, 2020
St. Nicholas was the Defender of Orthodoxy, Wonderworker, Holy Hierarch, Bishop of Myra. The Icon showed him with a halo, dressed in clerical garb, and holding a book of the scriptures in his left hand while making the hand gesture for the sign of the ...
Beards, Daniel E.
core   +1 more source

Illustration of patient-reported outcome challenges and solutions in rare diseases: a systematic review in Cushing’s syndrome

open access: yesOrphanet Journal of Rare Diseases, 2018
Rare diseases are often not fully understood and efforts put in investigating it from patient perspective are usually met with challenges. We performed a systematic literature review (SLR) for the last 20 years in Cushing’s Syndrome (CS) to illustrate ...
Naomi Knoble   +3 more
doaj   +1 more source

Phosphoinositides and inositol phosphates as molecular glues

open access: yesFEBS Letters, EarlyView.
Inositol phosphates (IPs) and phosphoinositides (PIPs) regulate diverse eukaryotic processes. Beyond recruiting signaling proteins or acting as structural cofactors, recent studies suggest they mediate protein–protein interactions as natural molecular glues.
Aleshia Seaton‐Terry   +9 more
wiley   +1 more source

Delphi Panel Consensus Statement Generation: COVID-19 Vaccination Recommendations for Immunocompromised Populations in the European Union

open access: yesInfectious Diseases and Therapy
Introduction The coronavirus disease 2019 (COVID-19) pandemic has caused unprecedented pressure on healthcare systems globally. The lack of quality guidelines on the management of COVID-19 in rheumatologic disease, renal disease, hematological malignancy,
Jaya Paranilam   +5 more
doaj   +1 more source

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