Results 61 to 70 of about 450,172 (307)
The newfound relationship between extrachromosomal DNAs and excised signal circles
FEBS Letters, EarlyView.Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley +1 more source
Icon, Symbol and Values of Functional and Aesthetic Communication in Industrial Product Design
الاكاديمي, 2021 The icon and the symbol represent the constituents of the communication process, through their intellectual and philosophical concepts that have been addressed by the current research that it has touched upon their importance in conveying the design idea
Ziad Hatem Harbi
doaj +1 more source
ICON: It's Not Just for Corrections Anymore, Data Download, Iowa Department of Corrections, January 2010 [PDF]
, 2010 The Iowa Correctional Offender Network (ICON) is a data collection system that was first deployed in community corrections in 2000 after two years of planning, and was integrated with the institutions in 2004.
core
In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS
FEBS Letters, EarlyView.We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka +11 more
wiley +1 more source
Health and Quality of Life Outcomes, 2020 Objectives For valid and reliable assessment of patients’ Health-Related Quality of Life (HRQoL), it is crucial to use psychometrically robust instruments.
Murtuza Bharmal +4 more
doaj +1 more source
Structural biology of ferritin nanocages
FEBS Letters, EarlyView.Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley +1 more source
Infectious Diseases and TherapyIntroduction The United States Advisory Committee on Immunization Practices (ACIP) and the Centers for Disease Control (CDC) recommend COVID-19 vaccines for all immunocompromised individuals.
Kira Zhi Hua Lai +5 more
doaj +1 more source
Issues and development trends of modern Icon painting [PDF]
SHS Web of Conferences, 2019 The article is concerned with topical issues and problem points of modern icon painting: understanding meanings and the mission of the icon in society, position of the Church, issue of the canon in icon painting, commercialization of the icon painter’s ...
Bobreshova Marina
doaj +1 more source
Tropical variability simulated in ICON-A with a spectral cumulus parameterization [PDF]
, 2020 We implemented a spectral cumulus parameterization based on a cloud-resolving model (SC scheme) in the icosahedral nonhydrostatic atmospheric model (ICON-A).
Baba, Y., Giorgetta, M.
core +2 more sources
FEBS Letters, EarlyView.We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley +1 more source