Results 71 to 80 of about 146,661 (248)
Finding novel vulnerabilities of hypomorphic BRCA1 alleles
Molecular Oncology, EarlyView.Synthetic lethality screens performed to identify novel vulnerabilities often model complete gene loss, thereby overlooking patient‐derived hypomorphic mutations. In this study, we have performed genome‐wide CRISPR screens on BRCA1 hypomorphic mutations, showing BRCA1I26A behaves like wild‐type, while BRCA1R1699Q mimics deficiency. Furthermore, we have
Anne Schreuder +10 more
wiley +1 more source
[sound icon] Tribute to Elliot Carter, March 23, 2013 [PDF]
, 2013 This is the concert program of the [sound icon] Tribute to Elliot Carter performance on Saturday, March 23, 2013 at 8:00 p.m., at the Boston University Concert Hall, 855 Commonwealth Avenue, Boston, Massachusetts.
School of Music, Boston University
core +1 more source
Molecular Oncology, EarlyView.The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka +9 more
wiley +1 more source
jingcshi/ICON: Initial release
<p>Pre-release to obtain DOI.</p> <p><strong>Full Changelog</strong>: https://github.com/jingcshi/ICON/commits/v0.1.0-alpha</p ...
Jingchuan Shi
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Encuentro Internacional 'Dibujos que hablan' (Chile) - iCOn-MICs (EU COST Action), 16 January 2023
, 2023 Members of the Action will be participating online in the International Conference 'Dibujos que hablan' to be held at the Universidad de Santiago de Chile (see calendar of events https://dqh.cl/dqh8/).
alazaro2
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Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization
Molecular Oncology, EarlyView.In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu +13 more
wiley +1 more source
Sound Icon, Inaugural Concert: Acoustic Spaces, March 26, 2011 [PDF]
, 2011 This is the concert program of the Sound Icon, Inaugural Concert: Acoustic Spaces performance on Saturday, March 26, 2011 at 8:00 p.m., at the Boston University Concert Hall, 855 Commonwealth Avenue, Boston, Massachusetts.
School of Music, Boston University
core +1 more source
Poster, Avenue Icon, August 5, 2017
, 2017 An event poster for a performance by Avenue Icon on Saturday, August 5, 2017, at 7:30 PM for $10. The four band members are seen standing in water with their instruments.https://digitalcommons.usf.edu/bdj_studioat620_posters/1006/thumbnail ...
Studio at 620, , Avenue Icon
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Molecular Oncology, EarlyView.Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur +11 more
wiley +1 more source