Results 61 to 70 of about 117,111 (323)
Discovery of ICOS-targeted small molecules using affinity selection mass spectrometry screening
bioRxivInducible T cell co-stimulator (ICOS) is a positive immune checkpoint receptor expressed on the surface of activated T cells, which could promote cell function after being stimulated with ICOS ligand (ICOS-L).
Longfei Zhang +4 more
semanticscholar +1 more source
Journal for ImmunoTherapy of Cancer, 2021 We report a case of rapid eradication of melanoma brain metastases and simultaneous near-fatal encephalomyelitis following double immune checkpoint blockade.
S. Bjursten +12 more
semanticscholar +1 more source
Urbanonymic Terminology: Systems and Problems
Научный диалог, 2019 The article is focused on the problem of ordering and adaptation of modern Russian onomastic terminology to its foreign, especially Western European versions.
R. V. Razumov, S. O. Goryaev
doaj +1 more source
Small Business Economics, 2020 Initial coin offerings (ICOs) are a novel form of funding that has driven billions of dollars into the blockchain ecosystem, potentially challenging traditional funding vehicles such as business angel or venture capital investments.
M. Schückes, T. Gutmann
semanticscholar +1 more source
British Journal of Haematology, 2021 The inducible T‐cell co‐stimulator (ICOS) is a T‐cell receptor that, once bound to ICOS ligand (ICOSL) expressed on several cell types including the B‐cell lineage, plays a decisive role in adaptive immunity by regulating the interplay between B and T ...
E. Boggio +17 more
semanticscholar +1 more source
On Link Availability Probability of Routing Protocols for Urban Scenario in VANETs
, 2012 This paper presents the link availability probability. We evaluate and compare the link availability probability for routing protocols; Ad hoc On-demand Distance vector (AODV), Dynamic Source Routing (DSR) and Fisheye State Routing (FSR) for different ...
Javaid, N. +5 more
core +1 more source
Frontiers in Immunology, 2023 BackgroundChronic rhinosinusitis (CRS), whose prevalence and pathogenesis are age-related, is characterized by nasal tissue eosinophil infiltration.
Aina Zhou +8 more
doaj +1 more source
Tumor necrosis factor-alpha regulates the expression of inducible costimulator receptor ligand on CD34+ progenitor cells during differentiation into antigen presenting cells [PDF]
, 2001 The inducible costimulator receptor (ICOS) is a third member of the CD28 receptor family that regulates T cell activation and function. ICOS binds to a newly identified ligand on antigen presenting cells different from the CD152 ligands CD80 and CD86. We
Aicher, A +9 more
core
Attenuation of Experimental Autoimmune Myositis by Blocking ICOS-ICOS Ligand Interaction [PDF]
The Journal of Immunology, 2007 Abstract Polymyositis (PM) is an acquired, systemic, connective tissue disease characterized by the proximal muscle weakness and infiltration of mononuclear cells into the affected muscles. To understand its etiology and immunopathogenesis, appropriate animal model is required. It has been demonstrated that immunization with native human
Yasuhiro, Katsumata +9 more
openaire +2 more sources
A Means of Assessing Deep Learning-Based Detection of ICOS Protein Expression in Colon Cancer
Cancers, 2021 Simple Summary In this study, we propose a general artificial intelligence (AI) based workflow for applying deep learning to the problem of cell identification in immunohistochemistry-stained slides as a basis for quantifying nuclear staining biomarkers.
Md. Mostafa Kamal Sarker +8 more
semanticscholar +1 more source