Results 71 to 80 of about 1,273,243 (249)

LDAcoop: Integrating non‐linear population dynamics into the analysis of clonogenic growth in vitro

open access: yesMolecular Oncology, EarlyView.
Limiting dilution assays (LDAs) quantify clonogenic growth by seeding serial dilutions of cells and scoring wells for colony formation. The fraction of negative wells is plotted against cells seeded and analyzed using the non‐linear modeling of LDAcoop.
Nikko Brix   +13 more
wiley   +1 more source

ON ℐ^𝒦-CONVERGENCE OF SEQUENCES OF BI-COMPLEX NUMBERS

open access: yesПроблемы анализа
We propose the concept of ℐ^𝒦-convergence of sequences of bi-complex numbers. We explore the fundamental properties of this newly introduced notion and its relationships with other convergence ...
J. Hossain, S. Debnath
doaj   +1 more source

Crucial parameters for precise copy number variation detection in formalin‐fixed paraffin‐embedded solid cancer samples

open access: yesMolecular Oncology, EarlyView.
This study shows that copy number variations (CNVs) can be reliably detected in formalin‐fixed paraffin‐embedded (FFPE) solid cancer samples using ultra‐low‐pass whole‐genome sequencing, provided that key (pre)‐analytical parameters are optimized.
Hanne Goris   +10 more
wiley   +1 more source

The ethos of St. Florian’s knights

open access: yesSafety & Fire Technology, 2019
Aim: The presentation of preliminary considerations on the ethos of the profession of firefighter. Introduction: In addition to appropriate procedures and standards, the competences of persons who create an institution are an essential element of ...
Jan Krynicki
doaj   +1 more source

Redox regulation meets metabolism: targeting PRDX2 to prevent hepatocellular carcinoma

open access: yesMolecular Oncology, EarlyView.
PRDX2 acts as a central redox hub linking metabolic dysfunction‐associated steatohepatitis (MASH) to hepatocellular carcinoma (HCC). In normal hepatocytes, PRDX2 maintains redox balance and metabolic homeostasis under oxidative stress. In contrast, during malignant transformation, PRDX2 promotes oncogenic signaling, stemness, and tumor initiation ...
Naroa Goikoetxea‐Usandizaga   +2 more
wiley   +1 more source

Combining antibody conjugates with cytotoxic and immune‐stimulating payloads maximizes anti‐cancer activity

open access: yesMolecular Oncology, EarlyView.
Methods to improve antibody–drug conjugate (ADC) treatment durability in cancer therapy are needed. We utilized ADCs and immune‐stimulating antibody conjugates (ISACs), which are made from two non‐competitive antibodies, to enhance the entry of toxic payloads into cancer cells and deliver immunostimulatory agents into immune cells.
Tiexin Wang   +3 more
wiley   +1 more source

Ideals and Filters on Neutrosophic Topologies Generated by Neutrosophic Relations

open access: yesAxioms
Recently, Milles and Hammami presented and studied the concept of a neutrosophic topology generated by a neutrosophic relation. As a continuation in the same direction, this paper studies the concepts of neutrosophic ideals and neutrosophic filters on ...
Ravi P. Agarwal   +4 more
doaj   +1 more source

Particle therapy is ideal for the treatment of ocular melanomas [PDF]

open access: bronze, 2016
Kavita Mishra   +2 more
openalex   +1 more source

Tumor mutational burden as a determinant of metastatic dissemination patterns

open access: yesMolecular Oncology, EarlyView.
This study performed a comprehensive analysis of genomic data to elucidate whether metastasis in certain organs share genetic characteristics regardless of cancer type. No robust mutational patterns were identified across different metastatic locations and cancer types.
Eduardo Candeal   +4 more
wiley   +1 more source

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