Results 121 to 130 of about 8,120,287 (316)

Rational design of FRET sensor proteins based on mutually exclusive domain interactions

, 2013
Proteins that switch between distinct conformational states are ideal to monitor and control molecular processes within the complexity of biological systems.
Vinkenborg, J.L., Merkx, M., Golynskiy, M.V., Lindenburg, L.H.   +3 more
core   +1 more source

Decreased cold‐sensing function of the transient receptor potential channel TRPM8 from tailed amphibians

FEBS Open Bio, EarlyView.
Despite frogs avoiding low temperatures, examination of four salamander species revealed that none avoided cold and all possessed cold tolerance. Functional analysis of TRPM8, a cold sensor, showed that all salamander TRPM8s had lost their cold sensitivity.
Tadahiro Sawao, Daiki Kobayashi, Shogo Hori, Osamu Saitoh   +3 more
wiley   +1 more source

Lysine need of heavy broiler males applying the ideal protein concept.

Poultry Science, 2002
An experiment was conducted to measure the response of broiler males to dietary lysine progressing from 0.75 to 1.15% between 42 and 56 d of age. Chicks (Ross x Ross 308) were placed in floor pens (30 pens having 35 chicks each) of an open-sided house ...
A. Corzo, E. Moran, D. Hoehler
semanticscholar   +1 more source

Evolutionarily divergent DUF4465 domains have a common vitamin B12‐binding function

FEBS Open Bio, EarlyView.
We show that DUF4465 family proteins, widespread across bacteria from gut microbiomes, hydrothermal vents, and soil, share a common vitamin B12‐binding function. These augmented β‐jellyroll proteins bind vitamin B12 via extended loops. Our findings establish sequence‐diverse DUF4465 proteins as a widespread class of B12‐binding proteins, highlighting ...
Charlea Clarke, Michal Banasik, Rokas Juodeikis, Martin J. Warren, Richard W. Pickersgill   +4 more
wiley   +1 more source

Digestible methionine + cysteine: lysine ratios for growing meat-type quails

Ciência Rural, 2018
: The objective was to estimate the most appropriate digestible methionine + cysteine:lysine ratios for growing meat-type quails (Coturnix coturnix) from 1 to 21 days of age.
Mariana Resende de Castro, Sandra Regina Freitas Pinheiro, Jéssica Amaral Miranda, Leonardo da Silva Costa, Graziela Maria de Freitas Rocha, Renata Gomes de Oliveira, Paulo Gustavo Macedo de Almeida Martins   +6 more
doaj   +1 more source

Feasibility of microfluidic routes to monitor protein stability as a tool for bioprocessing

, 2010
During the bioprocessing of therapeutics, proteins may become damaged leading to modifications and changes in stability. This may, as a consequence, cause serious and potentially fatal side effects when administered to patients making damage ...
Remtulla, N.
core  

YIPFα1A expression is regulated by multilayered molecular mechanisms

FEBS Open Bio, EarlyView.
YIPFα1A, a five‐pass Golgi protein, is regulated at multiple layers. (1) Rare‐codon enrichment drives translation‐coupled mRNA decay. (2) A proximal 3′‐UTR element stabilizes mRNA. (3) A distal 3′‐UTR element included by alternate poly(A) site usage represses translation, which can be overridden by the proximal 3′‐UTR element.
Tokio Takaji, Yurika Nakanishi, Nobuhiro Nakamura   +2 more
wiley   +1 more source

Respostas de frangos de corte a aumentos graduais na relação entre treonina e lisina Broiler responses to graded increases in the threonine to lysine ratio

Ciência Rural, 2007
Um experimento foi conduzido com o objetivo de avaliar o efeito de relações crescentes entre treonina (Thr) e lisina (Lys) digestível em dietas de frangos de corte nas repostas produtivas dos 15 aos 37 dias de idade.
Josemar Berres, Sergio Luiz Vieira, Jorge Luis Bernardon Coneglian, Alexandra Reali Olmos, Dimitri Moreira de Freitas, Tatsi Carolina Kowal Bortolini, Guilherme Xavier da Silva   +6 more
doaj   +1 more source

Molecular dynamics simulations of positively selected codons in FcγRI reveal novel biochemical binding properties

FEBS Open Bio, EarlyView.
Evolutionary analysis across 32 placental mammals identified positive selection at residues H148 and W149 in the immune receptor FcγR1. Ancestral reconstruction combined with molecular dynamics simulations reveals how these mutations may influence receptor structure and dynamics, providing insight into the evolution of antibody recognition and immune ...
David A. Young, Omar Arias‐Gaguancela, Fiona Gibson, Morgan Grainger, Jodie Score, Amit Nathubhai, Mauricio Cafiero, Lee Richard Machado   +7 more
wiley   +1 more source

DESEMPENHO DE FRANGOS DE CORTE, SEXADOS, SUBMETIDOS A DIETAS FORMULADAS PELOS CONCEITOS DE PROTEÍNA BRUTA versus PROTEÍNA IDEAL PERFORMANCE OF SEXED BROILER BIRDS, SUBMITTED TO DIETS FORMULATED BY THE CONCEPTS OF CRUDE PROTEIN versus IDEAL PROTEIN

Ciência Rural, 2001
O trabalho foi conduzido no Setor de Avicultura do Departamento de Zootecnia da Universidade Federal de Santa Maria com o objetivo de verificar as respostas de desempenho de frangos de corte, criados com sexos separados, alimentados pelo conceito ...
Maria Olinda Bergamo Mendoza, Paulo Tabajara Chaves Costa, Lia Helena Katzer, Antonio Carlos Benetti, Zenita Bisognin Santi, José Nelson Welter   +5 more
doaj   +1 more source