Results 61 to 70 of about 4,671,172 (293)

Reconstructing enzyme evolution by protein engineering

FEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler, Markus R. Busch, Reinhard Sterner   +2 more
wiley   +1 more source

Calcium as a crucial cofactor for low density lipoprotein receptor folding in the endoplasmic reticulum [PDF]

, 2010
The family of low density lipoprotein (LDL) receptors mediate uptake of a plethora of ligands from the circulation and couple this to signaling, thereby performing a crucial role in physiological processes including embryonic development, cancer ...
Sub Cellular Protein Chemistry, Pena, F., van Zadelhoff, G., Braakman, L.J., Cellular Protein Chemistry, Dep Scheikunde, Jansens, A.   +6 more
core   +2 more sources

Redução dos níveis protéicos e suplementação com metionina e lisina em rações para poedeiras leves Decreasing dietary levels of crude protein and supplementation of methionine and lysine for light laying hens

Revista Brasileira de Zootecnia, 2006
O experimento foi realizado com o objetivo de avaliar o efeito da redução da PB e da suplementação de rações com aminoácidos industriais sobre o desempenho de poedeiras.
Edson Lindolfo da Silva, José Humberto Vilar da Silva, José Jordão Filho, Marcelo Luís Gomes Ribeiro, Terezinha Domiciano Dantas Martins, Fernando Guilherme Perazzo Costa   +5 more
doaj   +1 more source

Effects of Feeding Low Protein Diets with Different Energy-to-Protein Ratios on Performance, Carcass Characteristics, and Nitrogen Excretion of Broilers

Animals, 2023
This study shows the effects of feeding low protein (LP) diets with different energy-to-protein ratios were evaluated on the production parameters, carcass composition, meat quality, nitrogen retention, and excreta composition of broilers. A total of 576-
Patrik Strifler, Boglárka Horváth, Nikoletta Such, Valéria Farkas, László Wágner, Károly Dublecz, László Pál   +6 more
doaj   +1 more source

Investigating transcription factor dynamics in health and disease using FRAP

FEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj, Carolina Vazquez Garzon, Jose Joaquin Velasco, Janine N. Post   +3 more
wiley   +1 more source

Pattern matching and pattern discovery algorithms for protein topologies [PDF]

, 2001
We describe algorithms for pattern matching and pattern learning in TOPS diagrams (formal descriptions of protein topologies). These problems can be reduced to checking for subgraph isomorphism and finding maximal common subgraphs in a restricted ...
Viksna, J, Juris Víksna, Gilbert, D, David Gilbert   +3 more
core   +3 more sources

Crude protein reduction and digestible methionine+cystine and threonine to digestible lysine ratios in diets for Nile tilapia fingerlings Redução de proteína bruta e relações de metionina+cistina e treonina digestíveis com lisina digestível em dietas para alevinos de tilápia-do-nilo

Revista Brasileira de Zootecnia, 2009
The objective of the present study was to investigate crude protein reduction and the methionine+cystine and threonine to lysine ratios in diets for reversed Nile tilapia fingerlings (Oreochromis niloticus), Thai strain.
Moisés Quadros, Eduardo Arruda Teixeira Lanna, Juarez Lopes Donzele, Márvio Lobão Teixeira de Abreu, Felipe Barbosa Ribeiro, Sylvia Sanae Takishita   +5 more
doaj   +1 more source

Structure‐forward targeting of claudins with synthetic binders

FEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source

Postcard of Ideal Diner, White Horse Pike, Egg Harbor City, NJ

, 1929
This is an unused half-tone dot-matrix printed post card showing the Ideal Diner in Egg Harbor City, NJ. Advertising on post card: The Ideal Diner: White Horse Pike, Egg Harbor, NJ.

core   +1 more source

El PA denuncia falta de sensibilidad municipal para con los minusválidos

, 1991
El PA denuncia falta de sensibilidad por parte del gobierno municipal de Almería con las personas con diversidad funcional. En apoyo con varias asociaciones, proponen un plan de acción para la eliminación de barreras urbanísticas y arquitectónicas, y ...
Ideal
core   +1 more source