Results 91 to 100 of about 6,870,114 (256)
There is much talk of the knowledge economy, and the central role of ideas and knowledge in generating economic growth. This paper provides a brief review of the economic literature on how skills/ knowledge/ ideas might contribute to higher output or ...
David. C. Maré
core
Molecular Oncology, EarlyView.This study shows that copy number variations (CNVs) can be reliably detected in formalin‐fixed paraffin‐embedded (FFPE) solid cancer samples using ultra‐low‐pass whole‐genome sequencing, provided that key (pre)‐analytical parameters are optimized.
Hanne Goris +10 more
wiley +1 more source
Ideas y Valores, 1973 Louis Althusser / Juergen Habermas / Jean - Toussaint Desanti / Paul Ricoeur / Alfred Schmidt / Noël Mouloud / Ramon Garzón / Jorge Aurelio Diaz / Freddy Téllez / Fernando Urbina / Breve bibliografía sobre el tema de la ...
. Ideas y Valores
doaj
Policy Briefing: Implementing empirical ethics and rights - IDEAS for ensuring disability equity in research [PDF]
, 2019 Research collaboration between University of York, De Montfort University and Lancaster UniversityIn this policy briefing, we illustrate the development and potential of tools developed from commissioned public health research project where empirical ...
Atkin, Karl +3 more
core
Molecular Oncology, EarlyView.Methods to improve antibody–drug conjugate (ADC) treatment durability in cancer therapy are needed. We utilized ADCs and immune‐stimulating antibody conjugates (ISACs), which are made from two non‐competitive antibodies, to enhance the entry of toxic payloads into cancer cells and deliver immunostimulatory agents into immune cells.
Tiexin Wang +3 more
wiley +1 more source
Tumor mutational burden as a determinant of metastatic dissemination patterns
Molecular Oncology, EarlyView.This study performed a comprehensive analysis of genomic data to elucidate whether metastasis in certain organs share genetic characteristics regardless of cancer type. No robust mutational patterns were identified across different metastatic locations and cancer types.
Eduardo Candeal +4 more
wiley +1 more source
Friendships, Rivalries, and Trysts: Characterizing Relations between Ideas in Texts
, 2017 Understanding how ideas relate to each other is a fundamental question in many domains, ranging from intellectual history to public communication.
Card, Dallas +2 more
core +1 more source
Molecular Oncology, EarlyView.Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat +8 more
wiley +1 more source
Targeting p38α in cancer: challenges, opportunities, and emerging strategies
Molecular Oncology, EarlyView.p38α normally regulates cellular stress responses and homeostasis and suppresses malignant transformation. In cancer, however, p38α is co‐opted to drive context‐dependent proliferation and dissemination. p38α also supports key functions in cells of the tumor microenvironment, including fibroblasts, myeloid cells, and T lymphocytes.
Angel R. Nebreda
wiley +1 more source
Identifying Early Signals From Emerging Public Health Events Using Natural Language Processing
Interdisciplinary Perspectives on Infectious DiseasesTimely detection of emerging public health threats is challenging because the surveillance infrastructure is not yet tuned to the emerging threat. We attempt to identify three nonspecific early signals that might be common across emerging events: public ...
Kelly S. Peterson +7 more
doaj +1 more source