Results 101 to 110 of about 2,577,245 (300)

Ideas and Growth [PDF]

open access: yes
What is it about modern capitalist economies that allows them, in contrast to all earlier societies, to generate sustained growth in productivity and living standards?
Robert E. Lucas, Jr.
core  

Profiling neoadjuvant therapy response in rectal cancer using meta‐analysis of publicly available transcriptomic RNA‐seq datasets

open access: yesMolecular Oncology, EarlyView.
This study integrates publicly available transcriptomic datasets to identify molecular signatures associated with response to neoadjuvant chemoradiotherapy in locally advanced rectal cancer. By analyzing a combination of multiple cohorts with bioinformatics approaches, we reveal biological pathways and immune‐related features that may improve ...
Aleksandra Stanojevic   +10 more
wiley   +1 more source

Regulation of the lncRNA NEAT1 by p53‐ΔNp63 crosstalk modulates the DNA damage response and therapeutic efficacy in HNSCC

open access: yesMolecular Oncology, EarlyView.
In head and neck squamous cell carcinoma (HNSCC) p53 and p63 exert opposite roles on the transcription regulation of the lncRNA NEAT1. Under basal conditions, p53 levels are low and p63 represses NEAT1 expression. Upon genotoxic stress, p53 is rapidly induced, displacing p63 from the NEAT1 promoter leading to NEAT1 transcriptional activation and ...
Sara De Domenico   +5 more
wiley   +1 more source

Análisis de la noción del tiempo

open access: yes, 1954
Como homenaje a San Agustín en el decimosexto Centenario de su nacimiento (354-1954), publicamos en nuestra sección Textos Clásicos los apartes más importantes de su análisis de la noción del tiempo (libro undécimo, capítulos XIV a XXXIV de las ...
Ideas, y valores
core  

Sharing my practice [PDF]

open access: yes, 2018
In my research project I look at the intersecting lines of art and yoga and how the two are both founded around a practice. I explain what it means to share a practice and how I created workshops around art and yoga for the UPS community.
Caron, Elayna
core  

p190A/ARHGAP35 and p190B/ARHGAP5 proteins in endometrial cancer: a novel cancer‐relevant paralog interplay

open access: yesMolecular Oncology, EarlyView.
This study identifies ARHGAP5, in addition to the frequently mutated ARHGAP35, as significantly mutated in endometrial cancer. Mutations in both genes co‐occur and are associated with their correlated downregulation. Functional CRISPR studies show that both paralogs regulate similar pathways, including actin cytoskeleton organization.
Mathilde Pinault   +12 more
wiley   +1 more source

Topic Timelines for Enabling Close and Distant Reading of Discursive Shifts. A Pilot Case Using Periodicals of European Diabetes Organizations

open access: yesJournal of Open Humanities Data
In a project about the development of 20th-century patient organizations and their ideas about disease, we are investigating discursive shifts in the organizations’ periodicals—mostly magazines and newsletters—using topic modelling.
Ylva Söderfeldt   +3 more
doaj   +1 more source

Idea farming: it is a good idea to have bad ideas in science

open access: yesIdeas in Ecology and Evolution, 2017
There are few truly bad ideas in authentic science. We need to embrace science as a process- driven human endeavour to better understand the world around us. Products are important, but through better transparency, we can leverage ideas, good and bad, ours and others, to do better science. In a brief analysis here inspired by a recent discussion of the
openaire   +3 more sources

Extracellular matrix remodeling and immune reprogramming drive residual tumor progression of liver cancer after incomplete microwave ablation

open access: yesMolecular Oncology, EarlyView.
Incomplete microwave ablation (iMWA) of liver cancer triggers a biphasic progression in residual tumors. At Day 3, the microenvironment is characterized by acute inflammatory responses and extracellular matrix (ECM) remodeling. By Day 14, a profound shift occurs toward oncogenic signal transduction and immunosuppression, marked by macrophage ...
Yu Liu   +9 more
wiley   +1 more source

Seciedad colombiana de filosofía

open access: yesIdeas y Valores, 1978
EI dia 30 de marzo de 1978, se fundó en Bogotá la  Sociedad Colombiana de Filosofía. A continuacion publicamos el Acta de Fundación y los Estatutos de la Sociedad.
. Ideas y Valores
doaj  

Home - About - Disclaimer - Privacy