Results 91 to 100 of about 1,900,562 (304)

Análisis de la noción del tiempo

open access: yes, 1954
Como homenaje a San Agustín en el decimosexto Centenario de su nacimiento (354-1954), publicamos en nuestra sección Textos Clásicos los apartes más importantes de su análisis de la noción del tiempo (libro undécimo, capítulos XIV a XXXIV de las ...
Ideas, y valores
core  

CD47 promotes mitogen‐activated protein kinase and epithelial‐to‐mesenchymal transition molecular programs to drive prometastatic phenotypes in non‐small cell lung cancer

open access: yesMolecular Oncology, EarlyView.
Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau   +8 more
wiley   +1 more source

Cell‐cycle‐specific lesion evolution rather than inhibition of double‐strand‐break repair underpins cisplatin radiosensitization

open access: yesMolecular Oncology, EarlyView.
We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu   +10 more
wiley   +1 more source

Información Filosófica

open access: yesIdeas y Valores, 1980
Décimo Congreso Interamericano de Filosofía /  Quinto Simposio Latinoamericano de Lógica Matemática / Cuarto Foro Nacional de Filosofía / Segundo Coloquio Colombiano de Filosofía / Primer Encuentro Nacional de Investigadores de Filosofía / Sociedad ...
Valores Ideas y
doaj  

Transcriptional profiling of circulating extracellular vesicles from prebiopsy prostate cancer patients

open access: yesMolecular Oncology, EarlyView.
RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner   +14 more
wiley   +1 more source

Discusión sobre la independencia de Hispanoamérica

open access: yesIdeas y Valores, 1967
Dentro de las múltiples actividades de extensión cultural del Departamento de Filosofía y Humanidades de la Universidad Nacional se desarrollo el día 17 de octubre de 1966, una mesa redonda sobre el carácter de la Independencia Latinoamericana, Este tema
. Ideas y Valores
doaj  

Stimulator of interferon genes agonist augmented antitumor immunity of osimertinib in Egfr‐mutated lung cancer

open access: yesMolecular Oncology, EarlyView.
Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura   +19 more
wiley   +1 more source

Idea farming: it is a good idea to have bad ideas in science

open access: yesIdeas in Ecology and Evolution, 2017
There are few truly bad ideas in authentic science. We need to embrace science as a process- driven human endeavour to better understand the world around us. Products are important, but through better transparency, we can leverage ideas, good and bad, ours and others, to do better science. In a brief analysis here inspired by a recent discussion of the
openaire   +3 more sources

Vida de la filosofía [PDF]

open access: yes, 1951
Necrologías / Decreto número 1801 de 1954 (junio 8) / Resolución número 4 de 1954, junio 9 / Resolución número 6 de 1954, julio 7 / Efemérides / Congresos / Concursos / Publicaciones / Cursos y ...
Ideas y, Valores, Ideas y Valores, .
core  

Actividades de la Facultad

open access: yesIdeas y Valores, 1965
Conferencias; Expedicion; Actividad Cultural ...
Valores Ideas y
doaj  

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