Results 91 to 100 of about 4,350,325 (326)

Identification and breeding biology of the diving petrelsPelecanoides georgicusandP. urinatrix exsulat South Georgia [PDF]

, 1979
Margaret Payne, P. A. Prince
openalex   +1 more source

From omics to AI—mapping the pathogenic pathways in type 2 diabetes

FEBS Letters, EarlyView.
Integrating multi‐omics data with AI‐based modelling (unsupervised and supervised machine learning) identify optimal patient clusters, informing AI‐driven accurate risk stratification. Digital twins simulate individual trajectories in real time, guiding precision medicine by matching patients to targeted therapies.
Siobhán O'Sullivan, Lu Qi, Pierre Zalloua   +2 more
wiley   +1 more source

Age-related morphological changes of the pubic symphyseal surface: using three-dimensional statistical shape modeling

Scientific Reports
Computational analysis of the pubic symphyseal surface is widely used for accurate age estimation, offering quantitative precision through the detection of subtle morphological changes.
Yuyoung Kim, Kang-Woo Lee, Sookyoung Lee, Eun Jin Woo, Kyung-Seok Hu   +4 more
doaj   +1 more source

Why Do Nasolabial Folds Appear? Exploring the Anatomical Perspectives and the Role of Thread-Based Interventions

Diagnostics
The classification of nasolabial folds into three types, each with distinct causative factors and mechanisms, is explored. Age-related changes in facial skin and connective tissues are examined in detail, revealing variations across different facial ...
Gi-Woong Hong, Sehyun Song, Soo Yeon Park, Sang-Bong Lee, Jovian Wan, Kyung-Seok Hu, Kyu-Ho Yi   +6 more
doaj   +1 more source

The anabolic steroid stanozolol is a potent inhibitor of human MutT homolog 1

FEBS Letters, EarlyView.
MutT homolog 1 (MTH1) is a member of the NUDIX superfamily of enzymes and is an anticancer drug target. We show that stanozolol (Stz), an anabolic steroid, is an unexpected nanomolar inhibitor of MTH1. The X‐ray crystal structure of the human MTH1–Stz complex reveals a unique binding scaffold that could be utilized for future inhibitor development ...
Emma Scaletti Hutchinson, Robert Gustafsson Westergren, Ingrid Almlöf, Ann‐Sofie Jemth, Martin Scobie, Ulrika Warpman Berglund, Thomas Helleday, Pål Stenmark   +7 more
wiley   +1 more source

Aminoácidos no proteicos en algunas especies de la subfamilia Mimosoideae con énfasis en el género Acacia sensu lato

Botan‪ical Sciences, 2016
Los aminoácidos no protéicos de algunas especies en las tribus Acaciae, Ingeae y Mimoseae se investigaron por cromatografía de líquidos-espectrometría de masas a partir de extractos crudos de semillas y hojas.
Marcos Soto-Hernández, María de Lourdes Rico-Arce, Geoffrey Kite   +2 more
doaj   +1 more source

Mycobacterium tuberculosis sulfurtransferase SseA is activated by its neighboring gene product Rv3284

FEBS Letters, EarlyView.
Tuberculosis remains a global health challenge and new therapeutic targets are required. Here, we characterized SseA, a sulfurtransferase from Mycobacterium tuberculosis involved in macrophage infection, and its interaction with the newly identified protein SufEMtb that activates SseA enzymatic activity.
Giulia Di Napoli, Alex Fissore, Edoardo Salladini, Eleonora Raccuia, Simonetta Oliaro‐Bosso, Alessia Ruggiero, Rita Berisio, Milagros Medina, Adrian Velazquez‐Campoy, Salvatore Adinolfi, Mauro Marengo   +10 more
wiley   +1 more source

AUSTRALIAN WATER BUGS. THEIR BIOLOGY AND IDENTIFICATION (HEMIPTERA‐HETEROPTERA, GERROMORPHA & NEPOMORPHA. [PDF]

, 2004
Peter S. Cranston
openalex   +1 more source

Aβ42 promotes the aggregation of α‐synuclein splice isoforms via heterogeneous nucleation

FEBS Letters, EarlyView.
The aggregation of amyloid‐β (Aβ) and α‐synuclein (αSyn) is associated with Alzheimer's and Parkinson's diseases. This study reveals that Aβ aggregates serve as potent nucleation sites for the aggregation of αSyn and its splice isoforms, shedding light on the intricate interplay between these two pathogenic proteins.
Alexander Röntgen, Zenon Toprakcioglu, Michele Vendruscolo   +2 more
wiley   +1 more source

Zone identification in biology articles as a basis for information extraction [PDF]

, 2004
Yoko Mizuta, Nigel Collier
openalex   +1 more source