Results 21 to 30 of about 154,739 (326)

O reflexo socioeconômico da presença militar em um município da fronteira norte

Coleção Meira Mattos, 2021
O Brasil tem 588 municípios em sua Faixa de Fronteira, alguns dos quais em regiões ainda carentes de desenvolvimento, como os localizados no Arco Norte.
Carlos Henrique Arantes de Moraes, Dan Milli Pereira, Tássio Franchi   +2 more
doaj   +1 more source

Study on the mechanism of inhibiting patulin production by fengycin

Open Life Sciences, 2022
Penicillium expansum is the main cause of apple rot. Besides, it can also produce mycotoxin patulin (PAT). Therefore, the search for substances that can inhibit the activity and toxigenicity of P. expansum has become a hot research topic.
Fu Ruimin, Tang Wei, Zhang Hong, Zhang Yulian, Wang Ding, Chen Wuling   +5 more
doaj   +1 more source

El sindicalismo peronista en el Partido Justicialista de Córdoba y el parlamento provincial (1983-1989)

Secuencia, 2023
Este artículo reconstruye la inserción del sindicalismo peronista en el Partido Justicialista (PJ) de Córdoba durante la reconstrucción democrática (1983-1989).
Ernesto Roland, Camila Sapp, Juan Gerbaldo   +2 more
doaj   +1 more source

IDH mutation in glioma: molecular mechanisms and potential therapeutic targets

British Journal of Cancer, 2020
Isocitrate dehydrogenase (IDH) enzymes catalyse the oxidative decarboxylation of isocitrate and therefore play key roles in the Krebs cycle and cellular homoeostasis.
Sue Han, Yang Liu, Sabrina J. Cai, Mingyu Qian, Jianyi Ding, Mioara Larion, M. Gilbert, Chunzhang Yang   +7 more
semanticscholar   +1 more source

Tryptophan metabolism drives dynamic immunosuppressive myeloid states in IDH-mutant gliomas

Nature Cancer, 2021
The dynamics and phenotypes of intratumoral myeloid cells during tumor progression are poorly understood. Here we define myeloid cellular states in gliomas by longitudinal single-cell profiling and demonstrate their strict control by the tumor genotype ...
M. Friedrich, R. Sankowski, L. Bunse, M. Kilian, E. Green, Carina Ramallo Guevara, S. Pusch, Gernot Poschet, K. Sanghvi, M. Hahn, T. Bunse, Philipp Münch, H. Gegner, J. Sonner, Anna von Landenberg, Frederik Cichon, K. Aslan, Tim Trobisch, Lucas Schirmer, Denis Abu-Sammour, T. Kessler, M. Ratliff, D. Schrimpf, F. Sahm, C. Hopf, D. Heiland, O. Schnell, Jürgen Beck, C. Böttcher, Camila Fernández-Zapata, J. Priller, S. Heiland, I. Gutcher, F. Quintana, A. von Deimling, W. Wick, M. Prinz, M. Plattén   +37 more
semanticscholar   +1 more source

Echocardiographic Evaluation of Cardiac Dysfunction in Hemodialysis Patients with or without Intradialytic Hypertension [PDF]

International Journal of Medical Arts, 2022
Background: Intradialytic hypertension [IDH] is an increase in systolic blood pressure [SBP] of more than 10 mm Hg over pre-dialysis SBP, which is a serious consequence of hemodialysis [HD].
Mohamed Siam, Emad Allam, Ahmed Al-Adl, Tamer Abd Elkader, Marwa Byomy   +4 more
doaj   +1 more source

Characteristics and prognostic impact of IDH mutations in AML: a COG, SWOG, and ECOG analysis

Blood Advances, 2023
Key Points • IDH mutation did not abrogate the favorable prognostic impact of NPM1 mutation in AML for patients aged
Sara Zarnegar-Lumley, T. Alonzo, R. Gerbing, M. Othus, Zhuoxin Sun, R. Ries, Jim Wang, Amanda Leonti, M. Kutny, F. Ostronoff, J. Radich, F. Appelbaum, E. Pogosova-Agadjanyan, K. O'Dwyer, M. Tallman, M. Litzow, E. Atallah, T. Cooper, R. Aplenc, O. Abdel-Wahab, A. Gamis, S. Luger, H. Erba, R. Levine, E. Kolb, D. Stirewalt, S. Meshinchi, Katherine Tarlock   +27 more
semanticscholar   +1 more source

Updates on the WHO diagnosis of IDH-mutant glioma

Journal of Neuro-Oncology, 2023
The WHO classification of Tumors of the Central Nervous System represents the international standard classification for brain tumors. In 2021 the 5th edition (WHO CNS5) was published, and this review summarizes the changes regarding IDH-mutant gliomas ...
D. Reuss
semanticscholar   +1 more source

Postoperative risk of IDH-mutant glioma–associated seizures and their potential management with IDH-mutant inhibitors

Journal of Clinical Investigation, 2023
Seizures are a frequent complication of adult-type diffuse gliomas, and are often difficult to control with medications. Gliomas with mutations in isocitrate dehydrogenase 1 or 2 (IDHmut) are more likely than IDH–wild type (IDHwt) gliomas to cause ...
M. Drumm, Wenxia Wang, Thomas K. Sears, Kirsten Bell-Burdett, R. Javier, Kristen Y. Cotton, Brynna T. Webb, Kayla Byrne, D. Unruh, V. Thirunavu, Jordain Walshon, Alicia Steffens, Kathleen McCortney, R. Lukas, J. Phillips, Esraa Mohamed, John D. Finan, Lucas Santana-Santos, A. Heimberger, Colin Franz, J. Kurz, Jessica W. Templer, Geoff Swanson, C. Horbinski   +23 more
semanticscholar   +1 more source

Proteogenomic characterization of cholangiocarcinoma

Hepatology, EarlyView., 2022
Proteogenomic characterization of cholangiocarcinoma with therapeutic strategies Abstract Background and Aims Cholangiocarcinoma (CCA) is a highly heterogeneous cancer with limited understanding and few effective therapeutic approaches. We aimed at providing a proteogenomic CCA characterization to inform biological processes and treatment ...
Mengjie Deng, Peng Ran, Lingli Chen, Yunzhi Wang, Zixiang Yu, Ke Cai, Jinwen Feng, Zhaoyu Qin, Yanan Yin, Subei Tan, Yang Liu, Chen Xu, Guoming Shi, Yuan Ji, Jian‐Yuan Zhao, Jian Zhou, Jia Fan, Yingyong Hou, Chen Ding   +18 more
wiley   +1 more source