Results 31 to 40 of about 41,008 (260)

Development of a Prediction Model for Progression Risk in High‐Grade Gliomas Based on Habitat Radiomics and Pathomics

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To investigate the value of constructing models based on habitat radiomics and pathomics for predicting the risk of progression in high‐grade gliomas. Methods This study conducted a retrospective analysis of preoperative magnetic resonance (MR) images and pathological sections from 72 patients diagnosed with high‐grade gliomas (52 ...
Yuchen Zhu, Yuxi Gong, Weilin Xu, Xingjian Sun, Gefei Jiang, Lei Qiu, Kexin Shi, Mengxing Wu, Yinjiao Fei, Jinling Yuan, Jinyan Luo, Yurong Li, Yuandong Cao, Minhong Pan, Shu Zhou   +14 more
wiley   +1 more source

Alonso, Jimena, Fabiana Larrobla y Mariana Risso. Avanzar a tientas: cronología de las luchas por verdad y justicia: 1985 - 2015. Uruguay: Mastergraf, 2016

Historia y Memoria, 2019
Reseña crítica del libro Avanzar a tientas: cronología de las luchas por verdad y justicia: 1985 - 2015 de Jimena Alonso, Fabiana Larrobla y Mariana Risso.
Paula Zubillaga
doaj   +1 more source

Unraveling the Molecular Mechanisms of Glioma Recurrence: A Study Integrating Single‐Cell and Spatial Transcriptomics

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Glioma recurrence severely impacts patient prognosis, with current treatments showing limited efficacy. Traditional methods struggle to analyze recurrence mechanisms due to challenges in assessing tumor heterogeneity, spatial dynamics, and gene networks.
Lei Qiu, Yinjiao Fei, Jiaxuan Ding, Kexin Shi, Jinyan Luo, Yuchen Zhu, Xingjian Sun, Gefei Jiang, Yuandong Cao, Weilin Xu, Shu Zhou   +10 more
wiley   +1 more source

El suicidio como problema gubernamental en la ciudad de Córdoba, Argentina

Revista Ñanduty, 2019
En este trabajo me propongo indagar respecto de la producción social del suicidio como problema gubernamental en la ciudad de Córdoba/Argentina de los últimos años.
Santiago Manuel Romero
doaj   +1 more source

Association of CDKN2A/B Homozygous Deletion and Extent of Resection With Survival of Patients With WHO CNS5 Grade 4 Astrocytoma

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives WHO grade 4 astrocytomas are associated with poor prognosis, and their prognostic factors remain controversial. This study aimed to identify the prognostic factors and develop a management algorithm for these patients. Methods This study retrospectively included 151 CNS5 adult grade 4 astrocytomas from two medical centers.
Jiawei Cai, Guanglin Zhu, Qiu He, Chen Luo, Lingyun Zhuo, Xingfu Wang, Yiming Chen, Xiaoyong Chen, Wendong You, Jiaheng Xu, Yuanxiang Lin, Dezhi Kang, Shuai Wu, Zanyi Wu   +13 more
wiley   +1 more source

Updates in IDH-Wildtype Glioblastoma

Neurotherapeutics, 2022
Glioblastoma is the most aggressive primary brain tumor with a poor prognosis. The 2021 WHO CNS5 classification has further stressed the importance of molecular signatures in diagnosis although therapeutic breakthroughs are still lacking. In this review article, updates on the current and novel therapies in IDH-wildtype GBM will be discussed.
Jawad M. Melhem, Jay Detsky, Mary Jane Lim-Fat, James R. Perry   +3 more
openaire   +2 more sources

Engineered GM1 Intersects Between Mitochondrial and Synaptic Pathways to Ameliorate ALS Pathology

Advanced Science, EarlyView.
Amyotrophic Lateral Sclerosis (ALS) is a fatal neurodegenerative disease driven by genetic and molecular disruptions affecting energy balance, protein homeostasis, and stress responses in nerve cells. Studies using human and rodent models identified convergent defects in mitochondria and synaptic function.
Federica Pilotto, Tristan Dellazizzo Toth, Silvano Bond, Alexander Schmitz, Rim Diab, Sara Y. Ngo Tenlep, Brian Mooney, Silvia Erni, Martina Schobesberger, Olivier Scheidegger, Camille Peitsch, Smita Saxena   +11 more
wiley   +1 more source

Repertorios de legitimación e impugnación moral de las desigualdades. Un estudio de las fronteras simbólicas de clase en Gran Córdoba, Argentina (2003-2015)

Revista Mexicana de Ciencias Políticas y Sociales, 2019
Este artículo analiza los sentidos lego y las justificaciones morales que transmutan las desigualdades estructurales en diferencias significativas o simbólicas entre las clases sociales en familias de Gran Córdoba, Argentina.
Gonzalo Assusa
doaj   +1 more source

Early onset acute lymphocytic interstitial pneumonitis (ALIP) in COVID-19 pathophysiology: preliminary lung autopsy findings

Sri Lanka Journal of Medicine, 2021
Sri Lanka is one of few countries which has performed post mortem examinations in deaths due to SARS CoV-2 virus (COVID-19) infection. At the office of the Judicial Medical Officer of National Institute of Infectious Diseases (NIID)/Infectious Disease ...
S. D. C. Perera
doaj   +1 more source

Chloroplast Stress Signals Orchestrate Epidermis‐Specific Remodeling of Mitochondria and ER Under High Light

Advanced Science, EarlyView.
High light exposure triggers an epidermis‐specific remodeling of mitochondria and ER in Arabidopsis, driven by chloroplast‐derived signals. Live‐cell imaging shows that HL rapidly suppresses mitochondrial motility, followed by fusion‐driven elongation and ER cisternal expansion.
Evan R. Angelos, Hee‐Seung Choi, Jingzhe Guo, Andrea A. Zanini, Tessa M. Burch‐Smith, Emily Snyder, Matthew Part, Wilhelmina van de Ven, Manhoi Hur, Gerd Ulrich Balcke, Alain Tissier, Quanqing Zhang, Katayoon Dehesh   +12 more
wiley   +1 more source