Pulmonary Hypertension in Patients with Chronic Fibrosing Idiopathic Interstitial Pneumonias [PDF]
, 2015 Background Pulmonary hypertension (PH) is a common finding in patients with chronic fibrosing idiopathic interstitial pneumonias (IIP). Little is known about the response to pulmonary vasodilator therapy in this patient population.
Behr, Juergen +19 more
core +6 more sources
Plasma proteome analysis in patients with pulmonary arterial hypertension: an observational cohort study [PDF]
, 2017 BackgroundIdiopathic and heritable pulmonary arterial hypertension form a rare but molecularly heterogeneous disease group. We aimed to measure and validate differences in plasma concentrations of proteins that are associated with survival in patients ...
Abdul-Salam +29 more
core +1 more source
The role of endothelin-1 in pulmonary arterial hypertension. [PDF]
, 2014 Pulmonary arterial hypertension (PAH) is a rare but debilitating disease, which if left untreated rapidly progresses to right ventricular failure and eventually death. In the quest to understand the pathogenesis of this disease differences in the profile,
Chester, AH, Yacoub, MH
core +1 more source
Elevated serum levels of macrophage migration inhibitory factor and stem cell growth factor β in patients with idiopathic and systemic sclerosis associated pulmonary arterial hypertension. [PDF]
, 2015 Pulmonary arterial hypertension (PAH) can be idiopathic or secondary to autoimmune diseases, and it represents one of the most threatening complications of systemic sclerosis (SSc).
Alessandri, Cristiano +9 more
core +2 more sources
Pulmonary venous remodeling in COPD‐pulmonary hypertension and idiopathic pulmonary arterial hypertension [PDF]
Pulmonary Circulation, 2017 Pulmonary vascular arterial remodeling is an integral and well‐understood component of pulmonary hypertension (PH). In contrast, morphological alterations of pulmonary veins in PH are scarcely described. Explanted lungs (n = 101) from transplant recipients with advanced chronic obstructive pulmonary disease (COPD) and idiopathic pulmonary arterial ...
Andersen, Kasper Hasseriis +3 more
openaire +3 more sources
Echocardiography combined with cardiopulmonary exercise testing for the prediction of outcome in idiopathic pulmonary arterial hypertension [PDF]
, 2016 BACKGROUND: Right ventricular (RV) function is a major determinant of exercise intolerance and outcome in idiopathic pulmonary arterial hypertension (IPAH). The aim of the study was to evaluate the incremental prognostic value of echocardiography of the
Badagliacca, Roberto +11 more
core +1 more source
Anticoagulation in pulmonary arterial hypertension: a decision analysis
Pulmonary Circulation, 2019 Systemic anticoagulation may be beneficial in pulmonary arterial hypertension, but there is no randomized clinical trial data to guide therapeutic decision making, and current guidelines do not account for patient preferences or quality of life. Decision
Arun Jose +2 more
doaj +1 more source
Inhaled iloprost as third add-on therapy in idiopathic pulmonary arterial hypertension
Pulmonary Circulation, 2021 Triple combination therapy is suggested in current pulmonary arterial hypertension guidelines in case of unsatisfactory treatment with oral double combination therapy.
Caio J.C.S. Fernandes +4 more
doaj +1 more source
Pulmonary Circulation, 2019 Circular RNAs have continuous, stable, and covalently closed circular structures and are not easily degraded by nucleases, thus they are ideal serum biomarkers for detecting diseases.
Ying Zhang +6 more
doaj +1 more source
Oxygen therapy may worsen the survival rate in rats with monocrotaline-induced pulmonary arterial hypertension. [PDF]
PLoS ONE, 2018 Although oxygen therapy rapidly improves arterial oxygen saturation in idiopathic pulmonary arterial hypertension, the effects of chronic administration of oxygen are unknown.
Naoto Fujita +5 more
doaj +1 more source